Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chien-Sin Chen"'
Autor:
Louise Madeleine Ince, Coline Barnoud, Lydia Kay Lutes, Robert Pick, Chen Wang, Flore Sinturel, Chien-Sin Chen, Alba de Juan, Jasmin Weber, Stephan J. Holtkamp, Sophia Martina Hergenhan, Jennifer Geddes-McAlister, Stefan Ebner, Paola Fontannaz, Benjamin Meyer, Maria Vono, Stéphane Jemelin, Charna Dibner, Claire-Anne Siegrist, Felix Meissner, Frederik Graw, Christoph Scheiermann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Circadian rhythms have been shown to influence immune responses, but it is unclear whether this influences responses to vaccines. Here the authors show that dendritic cells migrate in a circadian rhythm meaning that interactions with T cells are alte
Externí odkaz:
https://doaj.org/article/4a62447920cd4f83a5fd19b48d8d06ab
Autor:
Chien-Sin Chen, 陳建炘
99
An immediate-early protein, Rta, is an important transcription factor required for initiating the lytic cycle of Epstein-Barr virus (EBV). Tripartite-motif 5 alpha (TRIM5alpha) is a restriction factor of retroviruses with the ubiquitin E3 lig
An immediate-early protein, Rta, is an important transcription factor required for initiating the lytic cycle of Epstein-Barr virus (EBV). Tripartite-motif 5 alpha (TRIM5alpha) is a restriction factor of retroviruses with the ubiquitin E3 lig
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/95531511975219839713
Publikováno v:
Current Opinion in Physiology. 19:73-79
The nervous system exerts potent control over the immune system. A wealth of recent data strongly implicate different branches of the peripheral nervous system in toning immunity, including the sympathetic and parasympathetic as well as the sensory n
Autor:
Barbara U. Schraml, Christoph Scheiermann, Coline Barnoud, Elisabeth Deindl, Sophia Martina Hergenhan, Johanna Salvermoser, Manuel Lasch, Stephan Holtkamp, Alba de Juan, Burak Kizil, Louise Ince, Jasmin Weber, Chien-Sin Chen, Chen Wang, Lydia Lutes, Dirk Baumjohann
Publikováno v:
The journal of experimental medicine, Vol. 218, No 8 (2021) P. e20202377
The Journal of Experimental Medicine
The Journal of Experimental Medicine
This study shows loss of sympathetic innervation to the popliteal lymph node to induce IFN-γ expression in CD8 T cells, causing expansion. This is rescued by β2 adrenergic receptor agonists, demonstrating the pro-inflammatory effect of loss of dire
Autor:
Violetta Pilorz, Chien-Sin Chen, Robert Pick, Julia Philippou-Massier, Leonie Holtermann, Dietmar Vestweber, Barbara U. Schraml, David Laubender, Coline Barnoud, Madeleine T. Schmitt, Louise Ince, Jörg Renkawitz, Stephan Holtkamp, Charna Dibner, Flore Sinturel, Henrik Oster, Michael Mühlstädt, Wolf-Henning Boehncke, Markus Sperandio, Stephane Jemelin, Cornelia Halin, Jasmin Weber, Christoph Scheiermann
Publikováno v:
Nature immunology, Vol. 22, No 11 (2021) pp. 1375-1381
Nature Immunology
Nature Immunology
Migration of leukocytes from the skin to lymph nodes (LNs) via afferent lymphatic vessels (LVs) is pivotal for adaptive immune responses1,2. Circadian rhythms have emerged as important regulators of leukocyte trafficking to LNs via the blood3,4. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718ee70f87b1736c9d1c717fb869dc86
https://archive-ouverte.unige.ch/unige:156505
https://archive-ouverte.unige.ch/unige:156505
Autor:
Alexandra Baecklund, Hong Jin, Philipp Müller, Oliver Soehnlein, Peter Libby, Christian Weber, W.E. Kempf, Michael Hristov, Chien-Sin Chen, Philip Wenzel, Michael Molitor, Markus Krane, Matthias Nahrendorf, Lars Maegdefessel, Anna-Sophia Zimmermann, Karl-Heinz Ladwig, Christoph Scheiermann, Anna-Lena Steinsiek, Julia Hinterdobler, Jana Wobst, Almut Meesmann, Thorsten Kessler, Hendrik B. Sager, Quinte Braster, Aldo Moggio, Maarten Hulsmans, Ingo Hilgendorf, Baiba Vilne, Carina Mauersberger, Simin Schott, Heribert Schunkert
Publikováno v:
European Heart Journal, 42(39), 4077-+. Oxford University Press
European Heart Journal
European heart journal, Vol. 42, No 39 (2021) pp. 4077-4088
Eur. Heart J. 42, 4077–4088 (2021)
European Heart Journal
European heart journal, Vol. 42, No 39 (2021) pp. 4077-4088
Eur. Heart J. 42, 4077–4088 (2021)
Aims Mental stress substantially contributes to the initiation and progression of human disease, including cardiovascular conditions. We aim to investigate the underlying mechanisms of these contributions since they remain largely unclear. Methods an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5791577d2759f300f425588a3e5d0546
https://mediatum.ub.tum.de/doc/1639710/document.pdf
https://mediatum.ub.tum.de/doc/1639710/document.pdf
Autor:
Eugene C. Butcher, Ania Bogoslowski, Christoph Scheiermann, Craig N. Jenne, Paul Kubes, Woo Young Lee, Douglas A. Steeber, Samer Alanani, David Masopust, Chien Sin Chen, Sathi Wijeyesinghe
Publikováno v:
Journal of Immunology, Vol. 204, No 9 (2020) pp. 2552-2561
The adaptive immune function of lymph nodes is dependent on constant recirculation of lymphocytes. In this article, we identify neutrophils present in the lymph node at steady state, exhibiting the same capacity for recirculation. In germ-free mice,
Autor:
Rainer Haas, Hanspeter Herzel, Werner Solbach, Leif E. Sander, Louise Ince, Marc Ehlers, Kerstin Kraus, Olaf Uhl, Ute Harrison, Anthony H. Tsang, David Druzd, Wenyan He, Alexei Leliavski, Berthold Koletzko, Christoph Scheiermann, Naoto Kawakami, Alba de Juan, Olga Matveeva, Henrik Oster, Christoph Schmal, Chien-Sin Chen, Ling Yao, Sophia Martina Hergenhan
Publikováno v:
Immunity, Vol. 46, No 1 (2017) pp. 120-132
Immunity
Immunity
Lymphocytes circulate through lymph nodes (LN) in search for antigen in what is believed to be a continuous process. Here, we show that lymphocyte migration through lymph nodes and lymph occurred in a non-continuous, circadian manner. Lymphocyte homi
Publikováno v:
Trends in Immunology
Trends in Immunology, Vol. 40, No 6 (2019) pp. 524-537
Trends in Immunology, Vol. 40, No 6 (2019) pp. 524-537
The number of leukocytes circulating in blood in mammals is under circadian control (i.e., ∼24h). We summarize here latest findings on the mechanisms governing leukocyte migration from the blood into various organs, focusing on the distinct leukocy
Publikováno v:
The FASEB Journal. 32