Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Chien-Kuo Lee"'
Autor:
Hanna Nowicka, Agata Sekrecka, Katarzyna Blaszczyk, Katarzyna Kluzek, Chan-Yu Chang, Joanna Wesoly, Chien-Kuo Lee, Hans A. R. Bluyssen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17635 (2023)
In addition to the canonical ISGF3 and non-canonical STAT2/IRF9 complexes, evidence is emerging of the role of their unphosphorylated counterparts in IFN-dependent and -independent ISG transcription. To better understand the relation between ISGF3 an
Externí odkaz:
https://doaj.org/article/384edfd98d3c4a7594ad37c2157ea4bb
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Enterovirus A71 (EV-A71) infection can induce encephalitis, which causes death or long-term neurological sequelae, especially in young children. Using a murine infection model, we searched for anti-EV-A71 agents, because effective therapies
Externí odkaz:
https://doaj.org/article/7142f68ce92d485c825b4e26108d7e61
Editorial: STATs and IRFs in Innate Immunity: From Transcriptional Regulators to Therapeutic Targets
Autor:
Chien-Kuo Lee, Hans A. R. Bluyssen
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/71f903accd194232812791eea2d74b4f
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Type I interferon (IFN-I) is induced during innate immune response and is required for initiating antiviral activity, growth inhibition, and immunomodulation. STAT1, STAT2, and STAT3 are activated in response to IFN-I stimulation. STAT1, STAT2, and I
Externí odkaz:
https://doaj.org/article/8f4436dc0d99495da2c39dc5ddcd7519
Autor:
Anna Piaszyk-Borychowska, Lajos Széles, Attila Csermely, Hsin-Chien Chiang, Joanna Wesoły, Chien-Kuo Lee, Laszlo Nagy, Hans A. R. Bluyssen
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Atherosclerosis is a chronic inflammatory disease of the blood vessels, characterized by atherosclerotic lesion formation. Vascular Smooth Muscle Cells (VSMC), macrophages (MΦ), and dendritic cells (DC) play a crucial role in vascular inflammation a
Externí odkaz:
https://doaj.org/article/7106f1ef129e4e4a928406676caa9708
Autor:
Ming-Hsun Tsai, Chien-Kuo Lee
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Type I interferon (IFN-I) is a pluripotent cytokine that modulates innate and adaptive immunity. We have previously shown that STAT3 suppresses IFN-I response in a manner dependent on its N-terminal domain (NTD), but independent of its DNA-binding an
Externí odkaz:
https://doaj.org/article/31843ba588e34068bc3a1d66ed91f2d6
Efficient Generation of Plasmacytoid Dendritic Cell from Common Lymphoid Progenitors by Flt3 Ligand.
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135217 (2015)
Dendritic cells (DCs), including conventional DCs (cDCs) and plasmacytoid DCs (pDCs) are critical for initiating and controlling the immune response. However, study of DC, particularly pDC, function is hampered by their low frequency in lymphoid orga
Externí odkaz:
https://doaj.org/article/7931c2fb2b5b4925bfc2e9fac5e77b74
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46292 (2012)
Elevated liver enzyme level is an outstanding feature in patients with dengue. However, the pathogenic mechanism of liver injury has not been clearly demonstrated. In this study, employing a mouse model we aimed to investigate the immunopathogenic me
Externí odkaz:
https://doaj.org/article/9189d34f0a9a4b398cba779900a62325
Autor:
Chien-Kuo Lee, 李建國
100
This research is aimed to discuss different types of Sexuality language and their meaning underneath. In every life, even though you do not speak Sexuality language, you might hear other people speak. The researches which relate to Sexuality
This research is aimed to discuss different types of Sexuality language and their meaning underneath. In every life, even though you do not speak Sexuality language, you might hear other people speak. The researches which relate to Sexuality
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/82965136484486392104
Autor:
Chien-Kuo Lee, 李建國
98
Previous studies show that there is a positive relationship between design awards and corporate performances. Design awards are widely perceived as indicators of business innovation. Participating in or organizing an international design awar
Previous studies show that there is a positive relationship between design awards and corporate performances. Design awards are widely perceived as indicators of business innovation. Participating in or organizing an international design awar
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/63163798701225648121