Zobrazeno 1 - 10
of 290
pro vyhledávání: '"Chien-Chen Lai"'
Autor:
Wesley Tien Chiang, Yao-Kai Chang, Wei-Han Hui, Shu-Wei Chang, Chen-Yi Liao, Yi-Chuan Chang, Chun-Jung Chen, Wei-Chen Wang, Chien-Chen Lai, Chun-Hsiung Wang, Siou-Ying Luo, Ya-Ping Huang, Shan-Ho Chou, Tzyy-Leng Horng, Ming-Hon Hou, Stephen P. Muench, Ren-Shiang Chen, Ming-Daw Tsai, Nien-Jen Hu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The K+ uptake system KtrAB is essential for bacterial survival in low K+ environments. The activity of KtrAB is regulated by nucleotides and Na+. Previous studies proposed a putative gating mechanism of KtrB regulated by KtrA upon binding to
Externí odkaz:
https://doaj.org/article/22979af054c246cc93ea86e4f5a579c0
Autor:
Ching-Hung Lin, Feng-Cheng Hsieh, Chien-Chen Lai, Wei-Chen Wang, Cheng-Yu Kuo, Chun-Chun Yang, Hsuan-Wei Hsu, Hon-Man-Herman Tam, Cheng-Yao Yang, Hung-Yi Wu
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-10 (2023)
Abstract During coronavirus infection, in addition to the well-known coronavirus genomes and subgenomic mRNAs, an abundance of defective viral genomes (DVGs) can also be synthesized. In this study, we aimed to examine whether DVGs can encode proteins
Externí odkaz:
https://doaj.org/article/3d786110869e40e0b4df8b66447191d3
Publikováno v:
Life, Vol 14, Iss 8, p 1043 (2024)
Primary Sjogren’s syndrome (pSS) is often concomitant with fibromyalgia (FM). Salivary gland sonography aids in the diagnosis of pSS. We aimed to discover, in primary FM patients, the presence of pSS in undiagnosed patients through salivary gland s
Externí odkaz:
https://doaj.org/article/c19c0c06bd42481281f1cbaa4721623e
Autor:
Ching-Hung Lin, BoJia Chen, Day-Yu Chao, Feng-Cheng Hsieh, Chien-Chen Lai, Wei-Chen Wang, Cheng-Yu Kuo, Chun-Chun Yang, Hsuan-Wei Hsu, Hon-Man-Herman Tam, Hung-Yi Wu
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Background In addition to the well-known coronavirus genomes and subgenomic mRNAs, the existence of other coronavirus RNA species, which are collectively referred to as noncanonical transcripts, has been suggested; however, their biological
Externí odkaz:
https://doaj.org/article/ff3f1f4251d44b85b63a233ba6668592
Autor:
Kuo-Tung Tang, Yu-Sin Chen, Mey-Fann Lee, Tzu-Ting Chen, Chien-Chen Lai, Chi-Chien Lin, Yi-Hsing Chen
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1419 (2024)
Background: Volatile organic compounds (VOC) are major indoor air pollutants. Previous studies reported an association between VOC exposure and allergic diseases. Here, we aimed to explore the relationship between VOC exposure and atopic dermatitis (
Externí odkaz:
https://doaj.org/article/82797c8bec894342b7f57d1d2561be01
Autor:
An Xu, Mo Liu, Mo-Fan Huang, Yang Zhang, Ruifeng Hu, Julian A. Gingold, Ying Liu, Dandan Zhu, Chian-Shiu Chien, Wei-Chen Wang, Zian Liao, Fei Yuan, Chih-Wei Hsu, Jian Tu, Yao Yu, Taylor Rosen, Feng Xiong, Peilin Jia, Yi-Ping Yang, Danielle A. Bazer, Ya-Wen Chen, Wenbo Li, Chad D. Huff, Jay-Jiguang Zhu, Francesca Aguilo, Shih-Hwa Chiou, Nathan C. Boles, Chien-Chen Lai, Mien-Chie Hung, Zhongming Zhao, Eric L. Van Nostrand, Ruiying Zhao, Dung-Fang Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
The dysregulation of the m6A epitranscriptomic networks have been reported to contribute to the development of gliomas. Here, the authors utilize induced pluripotent stem cell-derived astrocytes with a p53 mutation and demonstrate that mutant p53 upr
Externí odkaz:
https://doaj.org/article/e94f230ab56e49dfb83c91e1ccf71c9f
Autor:
Chien-Wen Huang, Yu-Sheng Lin, Wei-Chang Huang, Chien-Chen Lai, Han-Ju Chien, Nien-Jen Hu, Jiann-Hwa Chen
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 55, Iss 1, Pp 60-68 (2022)
Background: The global rise in nosocomial infections associated with gram-negative bacteria and the spread of multi-drug resistant Acinetobacter baumannii (MDR-AB) pose public health concerns. This study investigates the inhibitory effects and possib
Externí odkaz:
https://doaj.org/article/1f9036cb0da44d9fac6dd8b4556586cf
Autor:
Jia-Lin Shiu, Cheng-Kuei Wu, Song-Bin Chang, Yan-Jhih Sun, Yen-Ju Chen, Chien-Chen Lai, Wen-Tai Chiu, Wen-Tsan Chang, Kyungjae Myung, Wen-Pin Su, Hungjiun Liaw
Publikováno v:
Oncogenesis, Vol 9, Iss 12, Pp 1-14 (2020)
Abstract Human HLTF participates in the lesion-bypass mechanism through the fork reversal structure, known as template switching of post-replication repair. However, the mechanism by which HLTF promotes the replication progression and fork stability
Externí odkaz:
https://doaj.org/article/88f8fd3519004ed99af3d2198f271760
Autor:
An Xu, Mo-Fan Huang, Dandan Zhu, Julian A. Gingold, Danielle A. Bazer, Betty Chang, Donghui Wang, Chien-Chen Lai, Ihor R. Lemischka, Ruiying Zhao, Dung-Fang Lee
Publikováno v:
Frontiers in Genetics, Vol 11 (2021)
Osteosarcoma is one of the most frequent common primary malignant tumors in childhood and adolescence. Long non-coding RNAs (lncRNAs) have been reported to regulate the initiation and progression of tumors. However, the exact molecular mechanisms inv
Externí odkaz:
https://doaj.org/article/9e84eebc8a7546098fc8ae81b9b148a8
Publikováno v:
Organic Letters. 24:1996-2001
We report the insertion of Pd(II) into an originally achiral rotaxane producing two chiral metallorotaxanes: one is planar-chiral, with its two interlocked components both chelating nonequivalently to the metal center; the other is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c689317f8a509cac86d50cf9f259685
https://doi.org/10.1021/acs.orglett.2c00426
https://doi.org/10.1021/acs.orglett.2c00426