Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Chien Wei Lee"'
Autor:
Xiaobo Zhu, Mingde Cao, Kejia Li, Yau-Tsz Chan, Hon-Fai Chan, Yi-Wah Mak, Hao Yao, Jing Sun, Michael Tim-Yun Ong, Kevin Ki-Wai Ho, Chien-Wei Lee, Oscar Kuang-Sheng Lee, Patrick Shu-Hang Yung, Yangzi Jiang
Publikováno v:
Bioactive Materials, Vol 39, Iss , Pp 255-272 (2024)
Osteoarthritis (OA) is a major clinical challenge, and effective disease-modifying drugs for OA are still lacking due to the complicated pathology and scattered treatment targets. Effective early treatments are urgently needed to prevent OA progressi
Externí odkaz:
https://doaj.org/article/65efe12f07f7452db3d7098879962681
Autor:
Belle Yu-Hsuan Wang, Allen Wei-Ting Hsiao, Hoi Ting Shiu, Nicodemus Wong, Amanda Yu-Fan Wang, Chien-Wei Lee, Oscar Kuang-Sheng Lee, Wayne Yuk-Wai Lee
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background High dosage of dexamethasone (Dex) is an effective treatment for multiple diseases; however, it is often associated with severe side effects including muscle atrophy, resulting in higher risk of falls and poorer life quality of pa
Externí odkaz:
https://doaj.org/article/0a2116ecbdfb4c19ba4b5b75edf479c0
Autor:
Wei-Ting Lin, Hao-Hsiang Wu, Chien-Wei Lee, Yu-Fan Chen, Lawrence Huang, Jennifer Hui-Chun Ho, Oscar Kuang-Sheng Lee
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102102- (2024)
Acute lung injury (ALI) is a life-threatening condition with limited treatment options. The pathogenesis of ALI involves macrophage-mediated disruption and subsequent repair of the alveolar barriers, which ultimately results in lung damage and regene
Externí odkaz:
https://doaj.org/article/b094449b64fc48d8b3e309fe915326b0
Autor:
Belle Yu‐Hsuan Wang, Yi‐Fan Chen, Allen Wei‐Ting Hsiao, Wan‐Jing Chen, Chien‐Wei Lee, Oscar Kuang‐Sheng Lee
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 3, Pp 1349-1364 (2023)
Abstract Background The progressive deterioration of tissue–tissue crosstalk with aging causes a striking impairment of tissue homeostasis and functionality, particularly in the musculoskeletal system. Rejuvenation of the systemic and local milieu
Externí odkaz:
https://doaj.org/article/23783ed0d4b6483c995fcb927f8b1f17
Autor:
Belle Yu-Hsuan Wang, Allen Wei-Ting Hsiao, Nicodemus Wong, Yi-Fan Chen, Chien-Wei Lee, Wayne Yuk Wai Lee
Publikováno v:
Journal of Orthopaedic Translation, Vol 39, Iss , Pp 12-20 (2023)
Background: Primary sarcopenia is usually known as age-related skeletal muscle loss; however, other factors like endocrine, lifestyle and inflammation can also cause muscle loss, known as secondary sarcopenia. Although many studies have used differen
Externí odkaz:
https://doaj.org/article/fe1f58272cc148ddbb084de435d2bee4
Autor:
Sheng-Hung Wang, Jing-Yan Cheng, Hsiu-Hui Tsai, Tzu-Chi Lo, Jung-Tung Hung, Chun-Cheng Lin, Chien-Wei Lee, Yi-Hsuan Ho, Huan-Hsien Kuo, Alice L. Yu, John Yu
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-18 (2022)
Abstract Background In endothelial cells, phospholipase C (PLC) β1-activated Ca2+ is a crucial second messenger for the signaling pathways governing angiogenesis. PLCβ1 is inactivated by complexing with an intracellular protein called translin-asso
Externí odkaz:
https://doaj.org/article/02741782cf294cdcab418047b7ad9299
Autor:
Wan-Jing Chen, I-Hsuan Lin, Chien-Wei Lee, Kiyoshi Yoshioka, Yusuke Ono, Yu-Ting Yan, Yun Yen, Yi-Fan Chen
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract The balance among quiescence, differentiation, and self-renewal of skeletal muscle stem cells (MuSCs) is tightly regulated by their intrinsic and extrinsic properties from the niche. How the niche controls MuSC fate remains unclear. Ribonucl
Externí odkaz:
https://doaj.org/article/b33217eaebe144d4ab08ed918f732901
Autor:
Chien-Wei Lee, Yi-Fan Chen, Allen Wei-Ting Hsiao, Amanda Yu-Fan Wang, Oscar Yuan-Jie Shen, Belle Yu-Hsuan Wang, Lok Wai Cola Ho, Wei-Ting Lin, Chung Hang Jonathan Choi, Oscar Kuang-Sheng Lee
Publikováno v:
Journal of Advanced Research, Vol 39, Iss , Pp 73-88 (2022)
Introduction: The regenerative capacity of mesenchymal stromal cells or medicinal signaling cells (MSCs) is largely mediated by their secreted small extracellular vesicles (sEVs), and the therapeutic efficacy of sEVs can be enhanced by licensing appr
Externí odkaz:
https://doaj.org/article/ce36e7b18faa4f509488b9076466086f
Autor:
Chien Wei Lee, 李健瑋
103
Oral squamous cell carcinoma (OSCC) is one of the most common neoplasms worldwide. Previously, we identified the angiostatic agent tryptophanyl-tRNA synthetase (TrpRS) as a dysregulated protein in OSCC based on a proteomics approach. Herein,
Oral squamous cell carcinoma (OSCC) is one of the most common neoplasms worldwide. Previously, we identified the angiostatic agent tryptophanyl-tRNA synthetase (TrpRS) as a dysregulated protein in OSCC based on a proteomics approach. Herein,
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/70839124731956699576
Autor:
Tsai‐Hsien Hung, Jung‐Tung Hung, Chiao‐En Wu, Yenlin Huang, Chien‐Wei Lee, Chau‐Ting Yeh, Yi‐Hsiu Chung, Fei‐Yun Lo, Li‐Chun Lai, John K. Tung, John Yu, Chun‐Nan Yeh, Alice L. Yu
Publikováno v:
Hepatology Communications, Vol 6, Iss 1, Pp 194-208 (2022)
Recent studies support the development of cancer therapeutics to target Globo H‐ceramide, the most prevalent tumor‐associated carbohydrate antigen in epithelial cancers. Herein, we evaluated the expression of Globo H and its prognostic significan
Externí odkaz:
https://doaj.org/article/e49b3e59fb7343d799fb3ad7b081eafa