Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Chien Tai Hong"'
Publikováno v:
Therapeutic Advances in Psychopharmacology, Vol 11 (2021)
Background: Depression is a major nonmotor symptom of Parkinson’s disease (PD). However, few treatments exist for PD depression. Monoamine oxidase-B inhibitors (MAOB-Is) provide symptomatic relief for the motor symptoms of PD and exert antidepressi
Externí odkaz:
https://doaj.org/article/fd6368ab4173424e8dc71c69288bbb07
Autor:
Chen Yu Wang, Lung Chan, Dean Wu, Wen-Chou Chi, Chia-Feng Yen, Hua-Fang Liao, Chien Tai Hong, Tsan-Hon Liou
Publikováno v:
Frontiers in Neurology, Vol 10 (2020)
Background: As the disease progresses to moderate to advanced stages, people with Parkinson's disease (PwP) are likely to have various degrees of disability due to the motor and non-motor symptoms, such as ambulatory difficulty and cognitive impairme
Externí odkaz:
https://doaj.org/article/db43caaeed29449482b86417dd7515c9
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-17 (2024)
Abstract Neurodegenerative diseases, including Alzheimer’s Disease (AD) and Parkinson’s Disease (PD) are common complications of diabetes, arising from insulin resistance, inflammation, and other pathological processes in the central nervous syst
Externí odkaz:
https://doaj.org/article/dd18947940964d3fa93e6ee6984c255e
Publikováno v:
Diagnostics, Vol 10, Iss 9, p 684 (2020)
Brain-derived neurotrophic factor (BDNF) is an essential neurotrophin, responsible for neuronal development, function, and survival. Assessments of peripheral blood BDNF in patients with Parkinson’s disease (PD) previously yielded inconsistent resu
Externí odkaz:
https://doaj.org/article/fb54b229a2f84f059cbde8dfaf9cbf00
Autor:
Shennie Tan, Chien Tai Hong, Jia-Hung Chen, Lung Chan, Wen-Chou Chi, Chia-Feng Yen, Hua-Fang Liao, Tsan-Hon Liou, Dean Wu
Publikováno v:
Brain Sciences, Vol 10, Iss 6, p 337 (2020)
In older individuals, hand fine motor skill disability is associated with cognitive levels. Similarly, patients with moderate-to-advanced Parkinson’s disease (PD) often have cognitive dysfunction. Here, we investigated the association between hand
Externí odkaz:
https://doaj.org/article/d69e1c151f074cfb932a3bd2ceefe77a
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
ObjectivesCholinesterase inhibitors (ChEIs) are the mainstream treatment for delaying cognitive decline in Alzheimer’s disease (AD). Low vitamin B12 is associated with cognitive dysfunction, and its supplementation has been applied as the treatment
Externí odkaz:
https://doaj.org/article/e7c47910915b49bf94bf314513d1a478
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180021 (2017)
The presence of an intracranial aneurysm is contraindicated to recombinant tissue plasminogen activator (r-tPA) treatment for acute ischemic stroke. However, it is difficult to exclude asymptomatic intracranial aneurysms by using conventional, noncon
Externí odkaz:
https://doaj.org/article/50cfa437fc934daba79d895bdb0f464d
Publikováno v:
Diagnostics, Vol 14, Iss 21, p 2430 (2024)
Background: The role of the cerebellum in Parkinson’s disease (PD), particularly in tremor-dominant subtypes, is increasingly recognized. Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) provide anatomical and metabolic in
Externí odkaz:
https://doaj.org/article/cb1d8fb9c43b46b3970fb44bcc6f29f3
Publikováno v:
Journal of the Formosan Medical Association, Vol 123, Iss 6, Pp 727-728 (2024)
Externí odkaz:
https://doaj.org/article/46210eaaa5cc4fd7b12045df79d2d0a9
Publikováno v:
eLife, Vol 12 (2024)
Synaptic dysfunction plays a key role in Parkinson’s disease (PD), and plasma extracellular vesicle (EV) synaptic proteins are emerging as biomarkers for neurodegenerative diseases. Assessment of plasma EV synaptic proteins for their efficacy as bi
Externí odkaz:
https://doaj.org/article/a3fe1a02dad844d7bd620df3fae1d3d8