Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Chien Hsiang Hsu"'
Autor:
Caleb R. Hoopes, Francisco J. Garcia, Akash M. Sarkar, Nicholas J. Kuehl, David T. Barkan, Nicole L. Collins, Glenna E. Meister, Taylor R. Bramhall, Chien-Hsiang Hsu, Michael D. Jones, Markus Schirle, Michael T. Taylor
Publikováno v:
J Am Chem Soc
Tryptophan (Trp) plays a variety of critical functional roles in protein biochemistry however, owing to its low natural frequency and poor nucleophilicity, the design of effective methods for both single protein bioconjugation at Trp as well as for i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6244e387c3f84b3963192f9d784dd8
https://doi.org/10.1021/jacs.1c10536
https://doi.org/10.1021/jacs.1c10536
Autor:
Michael Ramirez, Satwik Rajaram, Robert J. Steininger, Daria Osipchuk, Maike A. Roth, Leanna S. Morinishi, Louise Evans, Weiyue Ji, Chien-Hsiang Hsu, Kevin Thurley, Shuguang Wei, Anwu Zhou, Prasad R. Koduru, Bruce A. Posner, Lani F. Wu, Steven J. Altschuler
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Cancer cells that survive initial drug treatment can persist in the presence of drugs. Here, the authors generate persister cells that are resistant to the EGFR tyrosine kinase inhibitor erlotinib and show by single cell analysis that multiple mechan
Externí odkaz:
https://doaj.org/article/bd1a3c50ad1a402d9bff233756a1c84e
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 34
Neurodegeneration arising from aging, injury, or diseases has devastating health consequences. Whereas neuronal survival and axon degeneration have been studied extensively, much less is known about how neurodegeneration affects dendrites, in part du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74be8e2246d393f1ffb381443a42f046
https://doi.org/10.1073/pnas.2204577119
https://doi.org/10.1073/pnas.2204577119
Autor:
Augustina Frimpong, Francisco Garcia, Chien-Hsiang Hsu, Michael Jones, Ning Guo, Hongjing Xia, Kevin Xie, Pamela Ting, Yi Yang
Publikováno v:
Blood. 140:11096-11096
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e6532b14d51126c8435d75ad65450a3
https://doi.org/10.1182/blood-2022-163265
https://doi.org/10.1182/blood-2022-163265
Neurodegeneration arising from aging, injury or disease has devastating health consequences. Whereas neuronal survival and axon degeneration have been studied extensively, much less is known about how neurodegeneration impacts dendrites. To develop a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c39a9ec5d35ad4def740728e0a71ac17
https://doi.org/10.1101/2021.08.09.455574
https://doi.org/10.1101/2021.08.09.455574
Autor:
Chien Hsiang Hsu, N. Ezgi Wood, Yu San Yang, Benjamin M. Sutter, Xi Wu, Yun Wang, Benjamin P. Tu, Andrew Lemoff, Matthias Heinemann, Masato Kato, Athanasios Litsios, Hamid Mirzaei
Publikováno v:
Cell, 177(3), 697-710. CELL PRESS
Yeast ataxin-2, also known as Pbp1 (polyA binding protein-binding protein 1), is an intrinsically disordered protein implicated in stress granule formation, RNA biology, and neurodegenerative disease. To understand the endogenous function of this pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70655f7ccd044e0241fa5d326fe96940
https://research.rug.nl/en/publications/399b704a-23c6-442f-a94d-cf7eb94d0a90
https://research.rug.nl/en/publications/399b704a-23c6-442f-a94d-cf7eb94d0a90
Autor:
Hoopes, Caleb R., Garcia, Francisco J., Sarkar, Akash M., Kuehl, Nicholas J., Barkan, David T., Collins, Nicole L., Meister, Glenna E., Bramhall, Taylor R., Chien-Hsiang Hsu, Jones, Michael D., Schirle, Markus, Taylor, Michael T.
Publikováno v:
Journal of the American Chemical Society; 4/13/2022, Vol. 144 Issue 14, p6227-6236, 10p
Publikováno v:
Cell
Cell, vol 178, iss 2
Cell, vol 178, iss 2
Chemotherapy is designed to induce cell death. However, at non-lethal doses, cancer cells can choose to remain proliferative or become senescent. The slow development of senescence makes studying this decision challenging. Here, by analyzing single-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5f3be4b68decc23f05b596c562f5af
https://europepmc.org/articles/PMC6688629/
https://europepmc.org/articles/PMC6688629/
Autor:
Adam D. Coster, Qi Wu, Steven J. Altschuler, Bruce A. Posner, Chien Hsiang Hsu, Jungseog Kang, Lani F. Wu, Shanshan Liu
Publikováno v:
Nature biotechnology
High-content, image-based screens enable the identification of compounds that induce cellular responses similar to those of known drugs but through different chemical structures or targets. A central challenge in designing phenotypic screens is choos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f2bf4c8afae3c08920d8af3aa88ce2
https://doi.org/10.1038/nbt.3419
https://doi.org/10.1038/nbt.3419
Autor:
Chi-Hung Huang, Chien-Hsiang Hsu
Publikováno v:
Journal of the Chinese Institute of Engineers. 38:355-361
Using the advantages of non-contact and full-field measurements, the optical technique called amplitude-fluctuation electronic speckle pattern interferometry (AF-ESPI) with out-of-plane setup is employed to investigate the free vibration of cantileve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a07a98ada9d65d7ade2aecfcf742cb5
https://doi.org/10.1080/02533839.2014.970351
https://doi.org/10.1080/02533839.2014.970351