Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chien Chiao Huang"'
Autor:
Wen-Wei Lin, I-Ju Chen, Ta-Chun Cheng, Yi-Ching Tung, Pei-Yu Chu, Chih-Hung Chuang, Yuan-Chin Hsieh, Chien-Chiao Huang, Yeng-Tseng Wang, Chien-Han Kao, Steve R Roffler, Tian-Lu Cheng
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160418 (2016)
Molecular weight markers that can tolerate denaturing conditions and be auto-detected by secondary antibodies offer great efficacy and convenience for Western Blotting. Here, we describe M&R LE protein markers which contain linear epitopes derived fr
Externí odkaz:
https://doaj.org/article/a76b234ba50a438da1c8caeb587d2610
Autor:
Chien-Chiao Huang, Kung-Kai Kuo, Ta-Chun Cheng, Chih-Hung Chuang, Chien-Han Kao, Yuan-Chin Hsieh, Kuang-Hung Cheng, Jaw-Yuan Wang, Chiu-Min Cheng, Chien-Shu Chen, Tian-Lu Cheng
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133470 (2015)
The development of effective adjuvant is the key factor to boost the immunogenicity of tumor cells as a tumor vaccine. In this study, we expressed membrane-bound granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-18 (IL-18) as
Externí odkaz:
https://doaj.org/article/34e1dd7fa14d4f588fdcb3350f69ff62
Autor:
Chien-Chiao Huang, Yi-An Cheng, Yi-Ching Tung, Wen-Wei Lin, Shyng-Shiou F. Yuan, Yun-Chi Lu, Kai-Wen Cheng, Chiu-Min Cheng, Tian-Lu Cheng, I-Ju Chen, Bo-Cheng Huang, Yuan-Chin Hsieh
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Membrane antigens (mAgs) are important targets for the development of antibody (Ab) drugs. However, native mAgs are not easily prepared, causing difficulties in acquiring functional Abs. In this study, we present a platform in which human mAgs were e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c9826bd60418d2162385428f97e4b5
http://link.springer.com/article/10.1038/s41598-019-45160-9
http://link.springer.com/article/10.1038/s41598-019-45160-9
Autor:
Chiu-Min Cheng, Shey-Cherng Tzou, Ya-Han Zhuang, Chien-Chiao Huang, Chien-Han Kao, Kuang-Wen Liao, Ta-Chun Cheng, Chih-Hung Chuang, Yuan-Chin Hsieh, Ming-Hong Tai, Tian-Lu Cheng
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97367 (2014)
Single-chain variable fragments (scFvs) serve as an alternative to full-length monoclonal antibodies used in research and therapeutic and diagnostic applications. However, when recombinant scFvs are overexpressed in bacteria, they often form inclusio
Externí odkaz:
https://doaj.org/article/fadea00e77d54de7841f016df53dba0a
Autor:
I-Ju Chen, Kai-Wen Cheng, Chien-Chiao Huang, Tian-Lu Cheng, Yun-Chi Lu, Yi-An Cheng, Fang-Ming Chen, Ta-Chun Cheng, Yuan-Chin Hsieh, Shey Cherng Tzou, Chih-Hung Chuang, Yeng-Tseng Wang, Wen-Wei Lin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Systemic injection of therapeutic antibodies may cause serious adverse effects due to on-target toxicity to the antigens expressed in normal tissues. To improve the targeting selectivity to the region of disease sites, we developed protease-activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4368713a19a59365f810366200252e
http://link.springer.com/article/10.1038/s41598-017-11886-7
http://link.springer.com/article/10.1038/s41598-017-11886-7
Autor:
Kuo-Hsiang Chuang, Yuan-Chin Hsieh, Tian-Lu Cheng, I-Ju Chen, Steve R. Roffler, Yi-An Cheng, Kai-Wen Cheng, Wen-Wei Lin, Chien-Chiao Huang, Yeng-Tseng Wang, Yun-Chi Lu, Ta-Chun Cheng, Chih-Hung Chuang
Publikováno v:
Analytical chemistry. 88(24)
Sensitive determination of the pharmacokinetics of PEGylated molecules can accelerate the process of drug development. Here, we combined different anti-PEG Fab expressing 293T cells as capture cells (293T/3.3, 293T/6.3, and 293T/15–2b cells) with f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c45e92dc6950617bb4c0c0fa9a63577
https://pubmed.ncbi.nlm.nih.gov/28193011
https://pubmed.ncbi.nlm.nih.gov/28193011
Autor:
Jia Je Li, Chih Hung Chuang, Yuan Chin Hsieh, Ta Chun Cheng, Yeng-Tseng Wang, Tian-Lu Cheng, Chien Chiao Huang, Jaw-Yuan Wang, Hsin Ell Wang, Kuo-Hsiang Chuang, Wen-Wei Lin, Steve R. Roffler
Publikováno v:
Scientific Reports
Attachment of polyethylene glycol (PEG) molecules to nanoparticles (PEGylation) is a widely-used method to improve the stability, biocompatibility and half-life of nanomedicines. However, the evaluation of the PEGylated nanomedicine pharmacokinetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ff8cf36f52d0f35b9c9e6add2909db
https://doi.org/10.1038/srep39119
https://doi.org/10.1038/srep39119
Autor:
Tzer Min Kuo, Mong Liang Chen, Cheng Po Hu, Chien Chiao Huang, Chungming Chang, Yu Chi Chou, Ya Ling Chen, Chau Ting Yeh, Yue Lin Tsai
Publikováno v:
Virus Research. 174:18-26
Hepatitis B virus (HBV) is generally classified into eight genotypes (A to H) based on genomic sequence divergence. The sequence variation among the different HBV genotypes suggests that the spliced RNAs should be different from genotype to genotype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ea09cc693d321f54ccb6d095c653e5
https://doi.org/10.1016/j.virusres.2013.02.004
https://doi.org/10.1016/j.virusres.2013.02.004
Autor:
Chin Liew Chong, Mong Liang Chen, Kuen Nan Tsai, Chungming Chang, Chun-Hong Chen, Yu Chi Chou, Yi Ling Wang, Chien Chiao Huang, Shao Win Wang
Publikováno v:
Journal of virology. 89(22)
The risk of liver cancer in patients infected with the hepatitis B virus (HBV) and their clinical response to interferon alpha therapy vary based on the HBV genotype. The mechanisms underlying these differences in HBV pathogenesis remain unclear. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9acde982c7a1a2e915bf51aac56d35cd
https://pubmed.ncbi.nlm.nih.gov/26339052
https://pubmed.ncbi.nlm.nih.gov/26339052