Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chiel van Geffen"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Myeloid-derived suppressor cells (MDSCs) are a phenotypically heterogenous group of cells that potently suppress the immune response. A growing body of evidence supports the important role of MDSCs in a variety of lung diseases, such as asthma. Howev
Externí odkaz:
https://doaj.org/article/cdea9b790950488696e819a50b12fe68
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population with potent suppressive and regulative properties. MDSCs’ strong immunosuppressive potential creates new possibilities to treat chronic inflammation and autoimmune disease
Externí odkaz:
https://doaj.org/article/b45ee1843f3f42a3886df209bd377b4b
Autor:
Chiel van Geffen, Astrid Deißler, Sandra Beer-Hammer, Bernd Nürnberg, Rupert Handgretinger, Harald Renz, Dominik Hartl, Saeed Kolahian
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Emerging evidence suggests a mechanistic role for myeloid-derived suppressor cells (MDSCs) in lung diseases like asthma. Previously, we showed that adoptive transfer of MDSCs dampens lung inflammation in murine models of asthma through cyclooxygenase
Externí odkaz:
https://doaj.org/article/04980a933f934f31b517642ef2f5c94b
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The immune system is receiving increasing attention for interstitial lung diseases, as knowledge on its role in fibrosis development and response to therapies is expanding. Uncontrolled immune responses and unbalanced injury-inflammation-repair proce
Externí odkaz:
https://doaj.org/article/169cef844d3348fd89ddf6817e052dc7
Publikováno v:
Pharmacologytherapeutics. 241
Asthma is the most common airway chronic disease with treatments aimed mainly to control the symptoms. Adrenergic receptor agonists, corticosteroids and anti-leukotrienes have been used for decades, and the development of more targeted asthma treatme
Autor:
Irene Gonzalez-Menendez, Andrea Della Penna, Bernd Nürnberg, Anna Günther, Saeed Kolahian, Nicole Schneiderhan-Marra, Chiel van Geffen, Dominik Hartl, Markus Quante, Astrid Deißler, Alfred Königsrainer, Leticia Quintanilla-Martinez
Publikováno v:
Immunology letters. 236
Obesity has become a relevant problem in transplantation medicine with steadily increasing numbers of obese graft recipients. However, the effect of immunomodulatory drugs on transplant-related outcomes among obese patients are unknown. Therefore, we
Publikováno v:
Airway pharmacology and treatment.
Background: Previously, we showed that EP4 receptor agonist increases the number and suppressive activity of myeloid derived suppressor cells (MDSCs; both G-MDSCs and M-MDSCs) in the bone marrow culture in vitro. Methods: In the first part, mice were
Publikováno v:
Airway pharmacology and treatment.