Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Chieko Seno"'
Autor:
Chieko Seno, Osamu Miyazaki, Takeshi Onda, Eriko Toyoda, Shigehide Kagaya, Kazuya Okamoto, Kiyohiro Nishikawa
Publikováno v:
Cancer Letters. 259:99-110
NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes. The DNA breaks occurred within 1h after treatment with NK
Autor:
Taishi Maeda, Yasuo Nagaoka, Mineko Kurotaki, Chieko Seno, Sakiko Maruyama, Hiroshi Kuwajima, Shinichi Uesato
Publikováno v:
Bioorganicmedicinal chemistry. 12(16)
The screening tests of N-hydroxybenzamides for their HDAC-inhibitory activities led to the discovery of the promising compounds with a 2-naphthylcarbonyl group and with a 1,4-biphenylcarbonyl group. These compounds were further modified to optimize t
Autor:
Arihiro Tomura, Chieko Seno, Toshihiko Hayashi, Yasutada Imamura, Kazuhiro Tokunaka, Makoto Morita, Takamichi Sato, Kan Saiga, Hidemitsu Sugihara
Publikováno v:
Cancer Research. 71:557-557
Type IV collagen (COL-IV) is a major component of basement membrane (BM), comprising a polygonal meshwork structure underlying the basal side of polarized epithelia in normal tissues. Modulation of BM due to COL-IV degradation by matrix metalloprotei