Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Chieko Saito"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The formation of autophagosomes involves dynamic morphological changes of a phagophore from a flat membrane cisterna into a cup-shaped intermediate and a spherical autophagosome. However, the physical mechanism behind these morphological cha
Externí odkaz:
https://doaj.org/article/c41a3c8c3e29466aa516f903c043e45e
Publikováno v:
Cell Structure and Function, Vol 47, Iss 2, Pp 89-99 (2022)
In macroautophagy, disk-shaped double-membrane structures called phagophores elongate to form cup-shaped structures, becoming autophagosomes upon closure. These autophagosomes then fuse with lysosomes to become autolysosomes and degrade engulfed mate
Externí odkaz:
https://doaj.org/article/d21922effbf64de196871b111f7de41e
Autor:
Wenxin Zhang, Taki Nishimura, Deepanshi Gahlot, Chieko Saito, Colin Davis, Harold BJ Jefferies, Anne Schreiber, Lipi Thukral, Sharon A Tooze
Publikováno v:
eLife, Vol 12 (2023)
Autophagy is an essential catabolic pathway which sequesters and engulfs cytosolic substrates via autophagosomes, unique double-membraned structures. ATG8 proteins are ubiquitin-like proteins recruited to autophagosome membranes by lipidation at the
Externí odkaz:
https://doaj.org/article/532bcd67647149c3ad75104862f8b1ba
Autor:
Ayumi Yamagami, Chieko Saito, Miki Nakazawa, Shozo Fujioka, Tomohiro Uemura, Minami Matsui, Masaaki Sakuta, Kazuo Shinozaki, Hiroyuki Osada, Akihiko Nakano, Tadao Asami, Takeshi Nakano
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Brassinosteroids (BRs), plant steroid hormones, play important roles in plant cell elongation and differentiation. To investigate the mechanisms of BR signaling, we previously used the BR biosynthesis inhibitor Brz as a chemical biology tool
Externí odkaz:
https://doaj.org/article/0464ed82eb694adc87d1f063eb986632
Autor:
Takahiro Shimizu, Norito Tamura, Taki Nishimura, Chieko Saito, Hayashi Yamamoto, Noboru Mizushima
β-propellers that bind polyphosphoinositides (PROPPINs) are an autophagy-related protein family conserved throughout eukaryotes. The PROPPIN family includes Atg18, Atg21, and Hsv2 in yeast and WD-repeat protein interacting with phosphoinositides (WI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f596061e0415d4351c88f967e2829bf8
https://doi.org/10.1101/2023.03.08.531694
https://doi.org/10.1101/2023.03.08.531694
Autor:
Hiroyuki Uematsu, Chieko Saito, Jumpei Kondo, Kunishige Onuma, Roberto Coppo, Yukiko Mori, Manabu Mutou, Yuichiro Kikawa, Manami Tada, Tomoharu Sugie, Masahiro Inoue
Background Drug therapy of luminal-type breast cancer has advanced remarkably; however, its effectiveness continues to be limited by primary and acquired treatment resistance. To identify the means of overcoming such resistance, in vitro disease mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a38072dcbd866653bce7758eaab4796
https://doi.org/10.21203/rs.3.rs-2232037/v1
https://doi.org/10.21203/rs.3.rs-2232037/v1
Publikováno v:
Journal of Cell Biology. 221
A ferritin particle consists of 24 ferritin proteins (FTH1 and FTL) and stores iron ions within it. During iron deficiency, ferritin particles are transported to lysosomes to release iron ions. Two transport pathways have been reported: macroautophag
Autor:
Wenxin Zhang, Taki Nishimura, Gahlot, Deepanshi, Chieko Saito, Davis, Colin, Jefferies, Harold B. J., Schreiber, Anne, Thukral, Lipi, Tooze, Sharon A.
Publikováno v:
eLife; 6/23/2023, p1-26, 26p
The formation of autophagosomes involves dynamic morphological changes of a phagophore from a disk-shaped membrane cisterna into a cup-shaped intermediate and a spherical autophagosome. However, the physical mechanism behind these morphological chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f02d183e9a5c148e6ab6473d63ebd5ba
https://doi.org/10.1101/2022.07.20.500884
https://doi.org/10.1101/2022.07.20.500884
Autor:
Wenxin Zhang, Taki Nishimura, Deepanshi Gahlot, Chieko Saito, Colin Davis, Harold B. J. Jefferies, Anne Schreiber, Lipi Thukral, Sharon A. Tooze
SummaryAutophagy is an essential catabolic pathway which sequesters and engulfs cytosolic substrates via autophagosomes, unique double-membraned structures. ATG8 proteins are ubiquitin-like proteins recruited to autophagosome membranes by lipidation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aeb03d881729188aed8368fe7a4c654e
https://doi.org/10.1101/2022.06.10.495627
https://doi.org/10.1101/2022.06.10.495627