Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Chieko Makino-Okamura"'
Autor:
Tianchen Zhao, Yuta Tani, Chieko Makino-Okamura, Morihito Takita, Chika Yamamoto, Eiki Kawahara, Toshiki Abe, Sota Sugiura, Hiroki Yoshimura, Taiga Uchiyama, Isato Yamazaki, Harumichi Ishigame, Takaharu Ueno, Kazu Okuma, Masatoshi Wakui, Hidehiro Fukuyama, Masaharu Tsubokura
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
This study investigates the neutralizing activity against the XBB1.5 variant and the ancestral strain in a population post-bivalent vaccination using a pseudo virus assay validated with authentic virus assay. While bivalent booster vaccination and pa
Externí odkaz:
https://doaj.org/article/0353279085f74420a99d71b4c5e96775
Autor:
Masaru Takeshita, Hidehiro Fukuyama, Katsuhiko Kamada, Takehisa Matsumoto, Chieko Makino-Okamura, Qingshun Lin, Machie Sakuma, Eiki Kawahara, Isato Yamazaki, Tomomi Uchikubo-Kamo, Yuri Tomabechi, Kazuharu Hanada, Tamao Hisano, Saya Moriyama, Yoshimasa Takahashi, Mutsumi Ito, Masaki Imai, Tadashi Maemura, Yuri Furusawa, Seiya Yamayoshi, Yoshihiro Kawaoka, Mikako Shirouzu, Makoto Ishii, Hideyuki Saya, Yasushi Kondo, Yuko Kaneko, Katsuya Suzuki, Koichi Fukunaga, Tsutomu Takeuchi
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106955- (2023)
Summary: Several antibody therapeutics have been developed against SARS-CoV-2; however, they have attenuated neutralizing ability against variants. In this study, we generated multiple broadly neutralizing antibodies from B cells of convalescents, by
Externí odkaz:
https://doaj.org/article/e2e3c31b08ae483eaf9d68617811b2ec
Autor:
Masaru Takeshita, Hidehiro Fukuyama, Katsuhiko Kamada, Takehisa Matsumoto, Chieko Makino-Okamura, Tomomi Uchikubo-Kamo, Yuri Tomabechi, Kazuharu Hanada, Saya Moriyama, Yoshimasa Takahashi, Hirohito Ishigaki, Misako Nakayama, Cong Thanh Nguyen, Yoshinori Kitagawa, Yasushi Itoh, Masaki Imai, Tadashi Maemura, Yuri Furusawa, Hiroshi Ueki, Kiyoko Iwatsuki-Horimoto, Mutsumi Ito, Seiya Yamayoshi, Yoshihiro Kawaoka, Mikako Shirouzu, Makoto Ishii, Hideyuki Saya, Yasushi Kondo, Yuko Kaneko, Katsuya Suzuki, Koichi Fukunaga, Tsutomu Takeuchi
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105596- (2022)
Summary: The use of therapeutic neutralizing antibodies against SARS-CoV-2 infection has been highly effective. However, there remain few practical antibodies against viruses that are acquiring mutations. In this study, we created 494 monoclonal anti
Externí odkaz:
https://doaj.org/article/e7753cf4b9224024873cebd24a1bbb2e
Autor:
Makoto Arita, Kei Ogawa, Kenji Kondo, Hironori Harada, Hidehiro Fukuyama, Kenichi Asano, Yoshihiro Hayashi, Chieko Makino-Okamura, Tatsuya Yamasoba, Masato Tanaka, Satoshi Yotsumoto, Tsuyoshi Yamane
Publikováno v:
Journal of Leukocyte Biology. 109:481-496
Neutrophils are generally considered as short-lived, homogenous, and terminally differentiated phagocytes that play crucial roles in conquering infection, although they occasionally cause severe collateral tissue damage or chronic inflammation. Recen
Autor:
Quingshun Lin, Chieko Makino-Okamura, Hidehiro Fukuyama, Ryota Sato, Tomohiro Kurosaki, Jason E. Shoemaker, Muying Wang
Publikováno v:
International Immunology. 32:499-507
Aluminum precipitates have long been used as adjuvants for human vaccines, but there is a clear need for safer and more effective adjuvants. Here we report in a mouse model that the psoriasis drug Oxarol ointment is a highly effective vaccine adjuvan
Autor:
Yoko, Niki, Naoko, Adachi, Masaki, Fukata, Yuko, Fukata, Shinichiro, Oku, Chieko, Makino-Okamura, Seiji, Takeuchi, Kazumasa, Wakamatsu, Shosuke, Ito, Lieve, Declercq, Daniel B, Yarosh, Tomas, Mammone, Chikako, Nishigori, Naoaki, Saito, Takehiko, Ueyama
Publikováno v:
The Journal of investigative dermatology.
Palmitoylation is a lipid modification involving the attachment of palmitic acid to a cysteine residue, thereby affecting protein function. We investigated the effect of palmitoylation of tyrosinase, the rate-limiting enzyme in melanin synthesis, usi
Requirement for memory B-cell activation in protection from heterologous influenza virus reinfection
Autor:
Yu Adachi, Yoshimasa Takahashi, Hidehiro Fukuyama, Ryo Shinnakasu, Ken Ishii, Chieko Makino-Okamura, Masatoshi Momota, Tomohiro Kurosaki, Sarah Leach, Takuya Yamamoto
Publikováno v:
International immunology. 31(12)
While two memory compartments, memory B cells and long-lived plasma cells, are thought to contribute to the successful establishment of memory recall responses, the unique roles of each cellular compartment are still unclear. Herein, by tracing influ
Autor:
Chieko Makino-Okamura, Hidehiro Fukuyama, Takashi Watanabe, Kimi Araki, Yoshimi Uchida, Ryo Takagi, Masato Tanaka, Naoki Ikeda, Satoshi Yotsumoto, Kenichi Asano, Takumi Shibuya, Masaki Ohmuraya, Hiroki Ikegami, Gen Nishitai, Kenta Kikuchi
Publikováno v:
Science Immunology. 3
Ly6Chi monocytes migrate to injured sites and induce inflammation in the acute phase of tissue injury. However, once the causes of tissue injury are eliminated, monocyte-derived macrophages contribute to the resolution of inflammation and tissue repa
Autor:
Naoki, Ikeda, Kenichi, Asano, Kenta, Kikuchi, Yoshimi, Uchida, Hiroki, Ikegami, Ryo, Takagi, Satoshi, Yotsumoto, Takumi, Shibuya, Chieko, Makino-Okamura, Hidehiro, Fukuyama, Takashi, Watanabe, Masaki, Ohmuraya, Kimi, Araki, Gen, Nishitai, Masato, Tanaka
Publikováno v:
Science immunology. 3(28)
Ly6C
Autor:
Lieve Declercq, Chieko Makino-Okamura, Seiji Takeuchi, Daniel B. Yaroch, Naoaki Saito, Chikako Nishigori, Yoko Niki
Publikováno v:
Pigment cellmelanoma research. 27(6)
Summary To gain insight for the role of mast cell-produced heparin in the regulation of epidermal homeostasis and skin pigmentation, we have investigated the effect of heparin on melanosome uptake and proinflammatory responses in normal human epiderm