Superior Colliculus to VTA pathway controls orienting response and influences social interaction in mice

Autor: Clément Solié, Alessandro Contestabile, Pedro Espinosa, Stefano Musardo, Sebastiano Bariselli, Chieko Huber, Alan Carleton, Camilla Bellone

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

Solié, Contestabile et al. show that the superior colliculus to ventral tegmental area (VTA) pathway encodes orienting behavior toward conspecifics, and modulates VTA dopamine neurons projecting onto dorsolateral striatum perturbing social interacti

Externí odkaz: https://doaj.org/article/8b1ec866b4cf4a789a8102d6c7e96006

NOS1 mutations cause hypogonadotropic hypogonadism with sensory and cognitive deficits that can be reversed in infantile mice

Autor: Konstantina Chachlaki, Andrea Messina, Virginia Delli, Valerie Leysen, Csilla Maurnyi, Chieko Huber, Gaëtan Ternier, Katalin Skrapits, Georgios Papadakis, Sonal Shruti, Maria Kapanidou, Xu Cheng, James Acierno, Jesse Rademaker, Sowmyalakshmi Rasika, Richard Quinton, Marek Niedziela, Dagmar L’Allemand, Duarte Pignatelli, Mirjam Dirlewander, Mariarosaria Lang-Muritano, Patrick Kempf, Sophie Catteau-Jonard, Nicolas J. Niederländer, Philippe Ciofi, Manuel Tena-Sempere, John Garthwaite, Laurent Storme, Paul Avan, Erik Hrabovszky, Alan Carleton, Federico Santoni, Paolo Giacobini, Nelly Pitteloud, Vincent Prevot

Publikováno v: Science Translational Medicine
Science Translational Medicine, 2022, 14 (665), pp.eabh2369. ⟨10.1126/scitranslmed.abh2369⟩
Science translational medicine, vol. 14, no. 665, pp. eabh2369

The nitric oxide (NO) signaling pathway in hypothalamic neurons plays a key role in the regulation of the secretion of gonadotropin-releasing hormone (GnRH), which is crucial for reproduction. We hypothesized that a disruption of neuronal NO synthase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b9ba2a2f53ed6983bfc3208da7475d
https://www.hal.inserm.fr/inserm-03841246

The claustrum-medial prefrontal cortex network controls attentional set-shifting

Autor: Roberta Leone, Rodrigo F. Salazar, Kazadi Ekundayo, Jean-Rodolphe Renfer, Chieko Huber, Alan Carleton, Sophie Mutel, Leon Fodoulian, Ivan Rodriguez, Olivier Gschwend

Publikováno v: bioRxiv

SUMMARYIn various mental disorders, dysfunction of the prefrontal cortex contributes to cognitive deficits. Here we studied how the claustrum (CLA), a nucleus sharing reciprocal connections with the cortex, may participate in these cognitive impairme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db0fea093b955f6ddce9bdb64f0dfad
https://doi.org/10.1101/2020.10.14.339259

Superior Colliculus to VTA pathway controls orienting response to conspecific stimuli

Autor: Chieko Huber, Pedro Espinosa, Alessandro Contestabile, Alan Carleton, Clément Prévost-Solié, Camilla Bellone, Stefano Musardo, Sebastiano Bariselli

Social behaviours characterize cooperative, mutualistic aggressive or parental interactions that occurs among conspecifics. Although several neuronal substrates of social behaviour have been identified, whether defined circuits are dedicated to speci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16eb23b0f48d293c66545657235d842f
https://doi.org/10.1101/735340