Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Chieko Hirotsu"'
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Akademický článek
Neuronal Cell Sheets of Cortical Motor Neuron Phenotype Derived from Human iPSCs
Autor: Noboru Suzuki, Nagisa Arimitsu, Jun Shimizu, Kenji Takai, Chieko Hirotsu, Yuji Ueda, Sueshige Wakisaka, Naruyoshi Fujiwara, Tomoko Suzuki
Publikováno v: Cell Transplantation, Vol 26 (2017)
Transplantation of stem cells that differentiate into more mature neural cells brings about functional improvement in preclinical studies of stroke. Previous transplant approaches in the diseased brain utilized injection of the cells in a cell suspen
Externí odkaz: https://doaj.org/article/51e63151f32f41cda9ce4e312e1ce492
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2
Female dominance of both spatial cognitive dysfunction and neuropsychiatric symptoms in a mouse model of Alzheimer’s disease
Autor: Naruyoshi Fujiwara, Erika Takada, Yoshiki Ikeda, Tomoko Suzuki, Yoko Okada, Kenji Takai, Masanori A. Murayama, Nagisa Arimitsu, Noboru Suzuki, Chieko Hirotsu, Jun Shimizu
Publikováno v: Experimental Animals
Alzheimer's disease (AD) is a prevalent neurological disorder affecting memory function in elderly persons. Indeed, AD exhibits abnormality in cognitive behaviors and higher susceptibility to neuropsychiatric symptoms (NPS). Various factors including
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54098856fb968552e87209dde5fe95b3
http://europepmc.org/articles/PMC8390308
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Dementia model mice exhibited improvements of neuropsychiatric symptoms as well as cognitive dysfunction with neural cell transplantation
Autor: Yoko Okada, Noboru Suzuki, Jun Shimizu, Nagisa Arimitsu, Chieko Hirotsu, Masanori A. Murayama, Kenji Takai, Naruyoshi Fujiwara, Erika Takada, Tomoko Suzuki
Publikováno v: Experimental Animals
Elderly patients with dementia suffer from cognitive dysfunctions and neuropsychiatric symptoms (NPS) such as anxiety and depression. Alzheimer's disease (AD) is a form of age-related dementia, and loss of cholinergic neurons is intimately associated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c30635008b3c1155086f268a9488c79
https://doi.org/10.1538/expanim.21-0008
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Interaction between SDF1 and CXCR4 Promotes Photoreceptor Differentiation via Upregulation of NFκB Pathway Signaling Activity in Pax6 Gene-Transfected Photoreceptor Precursors
Autor: Noboru Suzuki, Tomoko Suzuki, Erika Takada, Yuji Ueda, Hiroki Ueno, Nagisa Arimitsu, Chieko Hirotsu, Jun Shimizu, Sueshige Wakisaka
Publikováno v: Ophthalmic Research. 63:392-403
Background: CCL2 (also known as monocyte chemoattractant protein 1) and CX3CR1 (also known as Fractalkine receptor)-deficient mice have damaged photoreceptors. Objectives: We examined the interaction of SDF1 and CXCR4 on the differentiation of retina
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba723bfe66ed1bb5555cb875e0b1b05
https://doi.org/10.1159/000503929
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Roles of Reelin/Disabled1 pathway on functional recovery of hemiplegic mice after neural cell transplantation; Reelin promotes migration toward motor cortex and maturation to motoneurons of neural grafts
Autor: Nagisa Arimitsu, Masanori A. Murayama, Noboru Suzuki, Naruyoshi Fujiwara, Jun Shimizu, Kenji Takai, Sueshige Wakisaka, Yuji Ueda, Tomoko Suzuki, Chieko Hirotsu
Publikováno v: Experimental neurology. 320
Reelin is a large glycoprotein which regulates central nervous system (CNS) development. Dysfunctions of Reelin were reported on certain neuropsychiatric diseases. We examined involvement of Reelin pathway in functional recovery of hemiplegic mice af
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7910e19f6e15bfeba6e1a9645bbe844a
https://pubmed.ncbi.nlm.nih.gov/31185198
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