Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Chieko, Yokoyama"'
Autor:
Sachiko Kobayashi, Shunbun Kita, Daisuke Okuzaki, Yuya Fujishima, Michio Otsuki, Hisashi Kato, Yasuko Nishizawa, Kazuya Miyashita, Chieko Yokoyama, Atsunori Fukuhara, Eiichi Morii, Iichiro Shimomura
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105252- (2022)
Summary: Currently, no mouse models manifest calcification and thrombus formation, which is frequently associated with human atherosclerosis. We demonstrated that lack of Favine/CCDC3 in apoE knockout mice accelerated atherosclerosis accompanied by l
Externí odkaz:
https://doaj.org/article/5f890c2fec2f41df8bde2ae9965d59fe
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 11, Pp 2979-2987 (2013)
12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT) has long been considered a by-product of thromboxane A2 (TxA2) biosynthesis with no biological activity. Recently, we reported 12-HHT to be an endogenous ligand for BLT2, a low-affinity leukotri
Externí odkaz:
https://doaj.org/article/6554b279e69d48e0b3b9ddea4dc915eb
Autor:
Sachiko Kobayashi, Shunbun Kita, Daisuke Okuzaki, Yuya Fujishima, Michio Otsuki, Hisashi Kato, Yasuko Nishizawa, Kazuya Miyashita, Chieko Yokoyama, Atsunori Fukuhara, Eiichi Morii, Iichiro Shimomura
Publikováno v:
iScience. 25(11)
Currently, no mouse models manifest calcification and thrombus formation, which is frequently associated with human atherosclerosis. We demonstrated that lack of Favine/CCDC3 in apoE knockout mice accelerated atherosclerosis accompanied by large chol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994f2e208c8418e7df9f774c2f46bf1a
https://pubmed.ncbi.nlm.nih.gov/36281455
https://pubmed.ncbi.nlm.nih.gov/36281455
Autor:
Di Hu, Atsunori Fukuhara, Yugo Miyata, Chieko Yokoyama, Michio Otsuki, Shinji Kihara, Iichiro Shimomura
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56071 (2013)
Adiponectin is exclusively expressed in adipose tissues and exhibits protective effects against cardiovascular and metabolic diseases. It enhances AMP-activated kinase (AMPK) and peroxisome proliferator-activated receptor α (PPARα) signaling in the
Externí odkaz:
https://doaj.org/article/f2d103d399004385890759e7c0d04d24
Publikováno v:
Prostaglandins & Other Lipid Mediators. 133:49-52
Prostacyclin (PGI2) synthase (PGIS) and microsomal prostaglandin (PG) E synthase-1 (PGES-1) functionally couple with inducible cyclooxygenase-2 (COX-2) as their upstream enzymes to produce PGI2 and PGE2, respectively. Non-steroidal anti-inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006a7383a8eeb8ec280377edd067d903
https://doi.org/10.1016/j.prostaglandins.2017.05.001
https://doi.org/10.1016/j.prostaglandins.2017.05.001
Autor:
Michio Otsuki, Chieko Yokoyama, Toshiharu Onodera, Jihoon Shin, Atsunori Fukuhara, Iichiro Shimomura
Publikováno v:
Hormone and Metabolic Research. 49:380-387
The physiological function of DPP-4 in proteolytic inactivation of incretins has been well established, however, there is limited information on the expression and the significance of DPP-4 in white adipose tissue with regard to obesity. The objectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003eedabaa876c22de6044bcbcbac814
https://doi.org/10.1055/s-0043-100115
https://doi.org/10.1055/s-0043-100115
Autor:
Shuntaro Hara, Emiko Yoda, Chieko Yokoyama, Moe Akatsu, Yoshihito Nakatani, Yuka Sasaki, Tsubasa Ochiai, Hiroshi Kuwata, Yuri Yamakawa
Publikováno v:
Prostaglandins & Other Lipid Mediators. 153:106523
Prostacyclin (PGI2) synthase (PGIS) functions downstream of inducible cyclooxygenase COX-2 in the PGI2 biosynthetic pathway. Although COX-2 and PGI2 receptor (IP) are known to be involved in adipogenesis and obesity, the involvement of PGIS has not b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37160fdd2c3b9228b27991bc8d29d692
https://doi.org/10.1016/j.prostaglandins.2020.106523
https://doi.org/10.1016/j.prostaglandins.2020.106523
Autor:
Jihoon Shin, Chieko Yokoyama, Shunbun Kita, Iichiro Shimomura, Atsunori Fukuhara, Michio Otsuki, Toshiharu Onodera
Publikováno v:
Diabetes. 67(6)
Insulin desensitization occurs not only under the obese diabetic condition but also in the fasting state. However, little is known about the common secretory factor(s) that are regulated under these two insulin-desensitized conditions. Here, using da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5ffb312fcd4dffa5c0e6223456c383
https://pubmed.ncbi.nlm.nih.gov/29581126
https://pubmed.ncbi.nlm.nih.gov/29581126
Autor:
Min Liu, Takehiko Yokomizo, Yukihiko Sugimoto, Takao Shimizu, Shuh Narumiya, Takehiko Matsunobu, Kenji Kabashima, Kazuko Saeki, Tomoaki Koga, Satoshi Nakamizo, Toshiaki Okuno, Chieko Yokoyama
Publikováno v:
The Journal of Experimental Medicine
Leukotriene B4 (LTB4) receptor type 2 (BLT2) is a G protein–coupled receptor (GPCR) for 12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT) and LTB4. Despite the well-defined proinflammatory roles of BLT1, the in vivo functions of BLT2 remain e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cbc2ac4fea0edf7dfd6341c226f261
https://doi.org/10.1084/jem.20132063
https://doi.org/10.1084/jem.20132063
Publikováno v:
Life Sciences. 83:6-11
Zinc is known to modulate a wide variety of cellular functions including anti-inflammatory responses. We examined the intracellular signaling pathways that contribute to the regulation of interferon-gamma (IFN-gamma) by zinc in activated human Jurkat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9c221fe54bd3e289b47732e6c09051
https://doi.org/10.1016/j.lfs.2008.04.022
https://doi.org/10.1016/j.lfs.2008.04.022