Zobrazeno 1 - 3
of 3
pro vyhledávání: '"ChiehYing J. Chang"'
Autor:
Tracy L. Taylor, Douglas G. Batt, Lorell Discenza, ChiehYing J. Chang, Luisa Salter-Cid, Kim W. McIntyre, Myra Beaudoin Bertrand, Percy H. Carter, Yingru Zhang, Qingjie Liu, James R. Burke, Andrew J. Tebben, Zheng Yang, Joel C. Barrish, Rick Rampulla, Aberra Fura, Daniel W. Kukral, Joseph A. Tino, Punit Marathe, Huiping Zhang, Jun Dai, Qing Shi, Arvind Mathur, Kathleen M. Gillooly, Mark A. Pattoli, Mary T. Obermeier, Stacey Skala, Jodi K. Muckelbauer, George V. De Lucca, Rodney Vickery, Celia D’Arienzo
Publikováno v:
Journal of medicinal chemistry. 59(17)
Bruton’s tyrosine kinase (BTK) belongs to the TEC family of nonreceptor tyrosine kinases and plays a critical role in multiple cell types responsible for numerous autoimmune diseases. This article will detail the structure–activity relationships
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76adcd8fa57a42d6c3f428fea7946e0b
https://pubmed.ncbi.nlm.nih.gov/27531604
https://pubmed.ncbi.nlm.nih.gov/27531604
Autor:
Dawn K. Stetsko, Dominique Besse, Francois Caussade, Eric Nicolai, Brett R. Beno, Stacey Skala, Michele Launay, Dominique Potin, ChiehYing J. Chang, Suzanne J. Suchard, Patrice Malabre, Edwin J. Iwanowicz, Maud Fabreguette, Gordon Todderud, Daniel L. Cheney, Steven Sheriff, Joel C. Barrish, T. G. Murali Dhar, Diane Hollenbaugh
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1161-1164
LFA-1 (leukocyte function-associated antigen-1), is a member of the beta(2)-integrin family and is expressed on all leukocytes. The LFA-1/ICAM interaction promotes tight adhesion between activated leukocytes and the endothelium, as well as between T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098c92dff877c316b3ed356338a5ede3
https://doi.org/10.1016/j.bmcl.2004.12.007
https://doi.org/10.1016/j.bmcl.2004.12.007
Autor:
ChiehYing J. Chang, T. G. Murali Dhar, Michael A. Poss, Joel C. Barrish, Dawn K. Stetsko, Linda M. Phillips, Yingru Zhang, Michele Launay, Murray McKinnon, Dominique Potin, Suzanne J. Suchard, Wayne Vaccaro, Steven Sheriff, Dharmpal S. Dodd
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(7)
A new class of lymphocyte function-associated antigen-1 (LFA-1) antagonists is described. Elaboration of the 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold resulted in the synthesis of potent inhibitors of the LFA-1/ICAM-1 interaction. Along with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48a7ca76906ba580e4abcee5836f8e5
https://pubmed.ncbi.nlm.nih.gov/17291752
https://pubmed.ncbi.nlm.nih.gov/17291752