Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chieh-Ting Fang"'
Autor:
Chieh-Ting Fang, Hsiao-Hui Kuo, Oyundari Amartuvshin, Hwei-Jan Hsu, Sih-Long Liu, Jhong-Syuan Yao, Ling-Huei Yih
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Tubulin s-palmitoylation involves the thioesterification of a cysteine residue in tubulin with palmitate. The palmitate moiety is produced by the fatty acid synthesis pathway, which is rate-limited by acetyl-CoA carboxylase (ACC). While it i
Externí odkaz:
https://doaj.org/article/583238a4349d4a4fb59861f452e4077d
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Taxol is a first-line chemotherapeutic for numerous cancers, including the highly refractory triple-negative breast cancer (TNBC). However, it is often associated with toxic side effects and chemoresistance in breast cancer patients, which g
Externí odkaz:
https://doaj.org/article/82fb0be2fc6f4e98a6a1a8c0db16f08d
Publikováno v:
Cell Division, Vol 14, Iss 1, Pp 1-17 (2019)
Abstract Background At the onset of mitosis, the centrosome expands and matures, acquiring enhanced activities for microtubule nucleation and assembly of a functional bipolar mitotic spindle. However, the mechanisms that regulate centrosome expansion
Externí odkaz:
https://doaj.org/article/f2ff5fd7242b49bcace2ee507ede1ddf
Publikováno v:
Cancer Research. 83:1573-1573
Acetyl-CoA carboxylase (ACC), the rate-limiting enzyme in the de novo fatty acid synthesis pathway, is required for successful cell division in yeast, indicating that fatty acid synthesis may be regulated in order to properly safeguard nuclear and ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::776da9654cbda593ceff04cf4633ad55
https://doi.org/10.1158/1538-7445.am2023-1573
https://doi.org/10.1158/1538-7445.am2023-1573
Publikováno v:
Cell Death and Disease, Vol 11, Iss 8, Pp 1-18 (2020)
Cell Death & Disease
Cell Death & Disease
The heat shock protein 70 (HSP70) is a conserved molecular chaperone and proteostasis regulator that protects cells from pharmacological stress and promotes drug resistance in cancer cells. In this study, we found that HSP70 may promote resistance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01f24c242e6ca50239ab3a8adfa51b7
http://link.springer.com/article/10.1038/s41419-020-02919-7
http://link.springer.com/article/10.1038/s41419-020-02919-7
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 7, Iss 1, Pp 1-13 (2021)
Cell Death Discovery, Vol 7, Iss 1, Pp 1-13 (2021)
Taxol is a first-line chemotherapeutic for numerous cancers, including the highly refractory triple-negative breast cancer (TNBC). However, it is often associated with toxic side effects and chemoresistance in breast cancer patients, which greatly li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc4489be7bd3d6f7c5146f789c3c204
https://pubmed.ncbi.nlm.nih.gov/34016960
https://pubmed.ncbi.nlm.nih.gov/34016960
Publikováno v:
Cell Division
Cell Division, Vol 14, Iss 1, Pp 1-17 (2019)
Cell Division, Vol 14, Iss 1, Pp 1-17 (2019)
Background At the onset of mitosis, the centrosome expands and matures, acquiring enhanced activities for microtubule nucleation and assembly of a functional bipolar mitotic spindle. However, the mechanisms that regulate centrosome expansion and matu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1a2bf6017b28529bd4dd2c8616e0ff
http://europepmc.org/articles/PMC6511203
http://europepmc.org/articles/PMC6511203
Publikováno v:
Cancer Research. 79:2551-2551
The mammalian target of rapamycin (mTOR) mediates the coordination of cell growth and cell cycle progression in response to nutrient supply. It is frequently activated in cancers and confers resistance to anti-cancer drugs. Accumulated studies have d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9640398a4883a908a589702375c70b6
https://doi.org/10.1158/1538-7445.am2019-2551
https://doi.org/10.1158/1538-7445.am2019-2551
Publikováno v:
Cellular and molecular life sciences : CMLS. 73(20)
To establish a functional bipolar mitotic spindle, the centrosome expands and matures, acquiring enhanced activities for microtubule (MT) nucleation and assembly at the onset of mitosis. However, the regulatory mechanisms of centrosome maturation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36fd48f575893737ed598cd9f68817d
https://pubmed.ncbi.nlm.nih.gov/27137183
https://pubmed.ncbi.nlm.nih.gov/27137183
Publikováno v:
Cancer Research. 75:LB-083
A functional centrosome is essential for the assembly of a bipolar mitotic spindle and accurate chromosome segregation. Loss of centrosome integrity frequently occurs in transformed cells or in tumor tissues. Pathways maintaining the quality control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5613b19ffe07c2e6615402670f3a6c01
https://doi.org/10.1158/1538-7445.am2015-lb-083
https://doi.org/10.1158/1538-7445.am2015-lb-083