Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chieh-En J. Tseng"'
Autor:
Tewodros Mulugeta Dagnew, Chieh-En J. Tseng, Chi-Hyeon Yoo, Meena M. Makary, Anna E. Goodheart, Robin Striar, Tyler N. Meyer, Anna K. Rattray, Leyi Kang, Kendall A. Wolf, Stephanie A. Fiedler, Darcy Tocci, Hannah Shapiro, Scott Provost, Eleanor Sultana, Yan Liu, Wei Ding, Ping Chen, Marek Kubicki, Shiqian Shen, Ciprian Catana, Nicole R. Zürcher, Hsiao-Ying Wey, Jacob M. Hooker, Roger D. Weiss, Changning Wang
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110159- (2024)
Summary: Alcohol use disorder (AUD) is a disorder of clinical and public health significance requiring novel and improved therapeutic solutions. Both environmental and genetic factors play a significant role in its pathophysiology. However, the under
Externí odkaz:
https://doaj.org/article/103a05e692354997b207d886b6310c5d
Autor:
Nicole R. Zürcher, Erin C. Walsh, Rachel D. Phillips, Paul M. Cernasov, Chieh-En J. Tseng, Ayarah Dharanikota, Eric Smith, Zibo Li, Jessica L. Kinard, Joshua C. Bizzell, Rachel K. Greene, Daniel Dillon, Diego A. Pizzagalli, David Izquierdo-Garcia, Kinh Truong, David Lalush, Jacob M. Hooker, Gabriel S. Dichter
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The social motivation hypothesis of autism posits that autism spectrum disorder (ASD) is characterized by impaired motivation to seek out social experience early in life that interferes with the development of social functioning. This framew
Externí odkaz:
https://doaj.org/article/50a8db12b5304b53b3f2df122a799343
Autor:
Tonya M. Gilbert, Nicole R. Zürcher, Mary C. Catanese, Chieh-En J. Tseng, Maria A. Di Biase, Amanda E. Lyall, Baileigh G. Hightower, Anjali J. Parmar, Anisha Bhanot, Christine J. Wu, Matthew L. Hibert, Minhae Kim, Umar Mahmood, Steven M. Stufflebeam, Frederick A. Schroeder, Changning Wang, Joshua L. Roffman, Daphne J. Holt, Douglas N. Greve, Ofer Pasternak, Marek Kubicki, Hsiao-Ying Wey, Jacob M. Hooker
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Gene transcription is known to vary with age and sex, although the underlying mechanisms are unresolved. Here, the authors show that epigenetic enzymes known as HDACs, which regulate gene transcription, are increasingly expressed with age in the livi
Externí odkaz:
https://doaj.org/article/fd891fe0074148ad83476fb18c8b1d21
Ibudilast (MN-166) in amyotrophic lateral sclerosis- an open label, safety and pharmacodynamic trial
Autor:
Suma Babu, Baileigh G. Hightower, James Chan, Nicole R. Zürcher, Pia Kivisäkk, Chieh-En J. Tseng, Danica L. Sanders, Ashley Robichaud, Haruhiko Banno, Armineuza Evora, Akshata Ashokkumar, Lindsay Pothier, Sabrina Paganoni, Sheena Chew, Joanna Dojillo, Kazuko Matsuda, Mark Gudesblatt, James D. Berry, Merit E. Cudkowicz, Jacob M Hooker, Nazem Atassi
Publikováno v:
NeuroImage: Clinical, Vol 30, Iss , Pp 102672- (2021)
Ibudilast (MN-166) is an inhibitor of macrophage migration inhibitory factor (MIF) and phosphodiesterases 3,4,10 and 11 (Gibson et al., 2006; Cho et al., 2010). Ibudilast attenuates CNS microglial activation and secretion of pro-inflammatory cytokine
Externí odkaz:
https://doaj.org/article/6307ae02502a42e6a2a3542ec44d074d
Autor:
Gilmore, Natalie, Chieh-En J. Tseng, Maffei, Chiara, Tromly, Samantha L., Deary, Katryna B., McKinney, Isabella R., Kelemen, Jessica N., Healy, Brian C., Hu, Collin G., Ramos-Llordén, Gabriel, Masood, Maryam, Cali, Ryan J., Guo, Jennifer, Belanger, Heather G., Yao, Eveline F., Baxter, Timothy, Fischl, Bruce, Foulkes, Andrea S., Polimeni, Jonathan R., Rosen, Bruce R.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 5/7/2024, Vol. 121 Issue 19, p1-7, 53p
Autor:
Brian L. Edlow, Yelena G. Bodien, Timothy Baxter, Heather G. Belanger, Ryan J. Cali, Katryna B. Deary, Bruce Fischl, Andrea S. Foulkes, Natalie Gilmore, Douglas N. Greve, Jacob M. Hooker, Susie Y. Huang, Jessica N. Kelemen, W. Taylor Kimberly, Chiara Maffei, Maryam Masood, Daniel P. Perl, Jonathan R. Polimeni, Bruce R. Rosen, Samantha L. Tromly, Chieh-En J. Tseng, Eveline F. Yao, Nicole R. Zürcher, Christine L. Mac Donald, Kristen Dams-O'Connor
Publikováno v:
Journal of neurotrauma. 39(19-20)
Emerging evidence suggests that repeated blast exposure (RBE) is associated with brain injury in military personnel. United States (U.S.) Special Operations Forces (SOF) personnel experience high rates of blast exposure during training and combat, bu