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Suppressive effects of a cyanine dye against herpes simplex virus (HSV)-1 infection

Autor: Tsunetaka Ohta, Toshio Ariyasu, Shigeharu Fukuda, Chie Ushio, Shigeyuki Arai, Harumi Ariyasu

Publikováno v: Biomedical Research. 30:365-368

In this study, we demonstrate that a cyanine dye, lumin, significantly suppressed cytopathic effect by herpes simplex virus (HSV)-1 toward human amnionic FL cell and also it reduced replication of HSV-1 in a dose-dependent manner. In addition, lumin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1a2221f40f7969fb5d6486e7e3db1b
https://doi.org/10.2220/biomedres.30.365

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Establishment of Antihuman IFN-α8-Specific Monoclonal Antibodies and Their Application in the Enzyme-Linked Immunosorbent Assay (ELISA)

Autor: Hitomi Ohta, Chie Ushio, Tsunetaka Ohta, Harumi Ariyasu, Shigeharu Fukuda, Masashi Kurimoto, Toshio Ariyasu, Tohru Kayano, Miho Aga

Publikováno v: Journal of Interferon & Cytokine Research. 28:359-366

In the present study, we describe the generation of a series of anti-interferon-alpha8 (IFN-alpha8)-specific monoclonal antibodies (mAbs), their characterization, and the establishment of a sandwich enzyme-linked immunosorbent assay (ELISA) system fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f5c06975f3e13e110b738961d63354
https://doi.org/10.1089/jir.2007.0121

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The Combination of IFN-α2 and IFN-α8 Exhibits Synergistic Antiproliferative Activity on Renal Cell Carcinoma (RCC) Cell Lines Through Increased Binding Affinity for IFNAR-2

Autor: Mutsuko Taniguchi, Toshio Ariyasu, Madoka Taniai, Harumi Ariyasu, Yasuo Tsutsumi, Miho Aga, Shigeto Yamamoto, Yohei Mukai, Tsunetaka Ohta, Chie Ushio, Shigeharu Fukuda, Tadao Tanimoto

Publikováno v: Journal of Interferon & Cytokine Research. 27:517-524

Although there are at least 13 interferon-alpha (IFN-alpha) subtypes in humans, interactions between the subtypes remain unknown. To understand IFN-alpha interactions, we examined the antiproliferative activities and the receptor binding affinities o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98106b195dc2304389393c000c4e1a3b
https://doi.org/10.1089/jir.2007.0155

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Trehalose Protects Cells from Injury Caused by Acids or Cigarette Smoke Constituents (Studies on cytoprotective properties of trehalose)

Autor: Manabu Miyata, Toshio Ariyasu, Chiyo Yoshizane, Tsunetaka Ohta, Shigeharu Fukuda, Miho Aga, Chie Ushio, Shigeyuki Arai

Publikováno v: Nippon Shokuhin Kagaku Kogaku Kaishi. 54:374-378

トレハロースが口腔内細胞を酸やタバコなどの傷害物質から保護するかについて検討した．培養ヒト細胞粘膜モデルに酸またはタバコ煙成分と同時にトレハロースを添加し，傷害の程度�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d87b03275459c784adf5f863a153e6f
https://doi.org/10.3136/nskkk.54.374

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Inhibition of chlamydia trachomatis growth by human interferon-.ALPHA.: mechanisms and synergistic effect with interferon-.GAMMA. and tumor necrosis factor-.ALPHA

Autor: Keiko Hino, Masao Ikeda, Tatsuya Ishihara, Chie Ushio, Miho Aga, Mutsuko Taniguchi, Kanso Iwaki, Masashi Kurimoto

Publikováno v: Biomedical Research. 26:179-185

We have evaluated the effect of natural human interferon (IFN)-alpha on the growth of chlamydia trachomatis in human epithelial cells in vitro and revealed that IFN-alpha has reduced both growth and infectivity of C. trachomatis. The effect of IFN-al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b9de5fcd665a3d6e7a7827f1561687
https://doi.org/10.2220/biomedres.26.179

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Constitutive and Induced IL-18 Receptor Expression by Various Peripheral Blood Cell Subsets as Determined by Anti-hIL-18R Monoclonal Antibody

Autor: Hakuo Ikegami, Masashi Kurimoto, Takanori Okura, Kakuji Torigoe, Shimpei Ushio, Hiroshi Yamauchi, Masao Ikeda, Toshio Kunikata, Chie Ushio

Publikováno v: Cellular Immunology. 189:135-143

Interleukin-18 (IL-18) was identified as a molecule that induces IFN-gamma production and enhances NK cell cytotoxicity. Characterization of the receptor for human IL-18 (hIL-18R) is important for investigating the physiological role of IL-18 in natu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a622b92dd6c61a446c22b5692c362484
https://doi.org/10.1006/cimm.1998.1376

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