Zobrazeno 1 - 10
of 490
pro vyhledávání: '"Chie Kojima"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 715 (2024)
Dendrimers are potent nanocarriers in drug delivery systems because their structure can be precisely controlled. We previously reported that polyamidoamine (PAMAM) dendrimers that were modified with 1,2-cyclohexanedicarboxylic acid (CHex) and phenyla
Externí odkaz:
https://doaj.org/article/a998c5eb19ae4ce19351c22c08f3e575
Publikováno v:
Polymers, Vol 16, Iss 2, p 241 (2024)
The 2-methacryloyloxyethyl phosphorylcholine (MPC) polymers are mimetic to phospholipids, being widely used as biocompatible polymers. In our previous study, MPC polymer hydrogels proved more effective for optical tissue clearing compared to acrylami
Externí odkaz:
https://doaj.org/article/60c66100a383433fb1d8508ae45c7116
Autor:
Hiroya Shiba, Tomoka Hirose, Yunshen Fu, Masataka Michigami, Ikuo Fujii, Ikuhiko Nakase, Akikazu Matsumoto, Chie Kojima
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 888 (2023)
T cells play important roles in various immune reactions, and their activation is necessary for cancer immunotherapy. Previously, we showed that polyamidoamine (PAMAM) dendrimers modified with 1,2-cyclohexanedicarboxylic acid (CHex) and phenylalanine
Externí odkaz:
https://doaj.org/article/15571b38718d4c8bbdbfdd711fdcd37f
Publikováno v:
ACS Omega, Vol 4, Iss 25, Pp 21083-21090 (2019)
Externí odkaz:
https://doaj.org/article/187419a1f2fe47fea17e0670e8c96f51
Autor:
Chie Kojima, Kento Nagai
Publikováno v:
Polymers, Vol 14, Iss 20, p 4314 (2022)
Detection of cancer metastasis spread in lymph nodes is important in cancer diagnosis. In this study, a fluorescence imaging probe was designed for the detection of both lymph node and tumor cells using always-ON and activatable fluorescence probes w
Externí odkaz:
https://doaj.org/article/60fbb681dbc6465d83331116c081182b
Publikováno v:
Polymers, Vol 14, Iss 12, p 2426 (2022)
Stimuli-sensitive materials, such as pH- and temperature-responsive polymers, are useful as smart materials. Phenylalanine (Phe)-modified polyamidoamine (PAMAM) dendrimers with succinic acid termini, PAMAM-Phe-Suc, have been reported as unique pH-swi
Externí odkaz:
https://doaj.org/article/13f687d7f15246c9ad3330e4c5121557
Publikováno v:
Polymer Journal. 55:63-73
Publikováno v:
Polymers, Vol 13, Iss 16, p 2805 (2021)
2-Methacryloyloxyethyl phosphorylcholine (MPC) polymers have been used as a coating agent on medical devices and as a carrier in drug delivery systems (DDSs). Paclitaxel (PTX) is a water-insoluble anticancer drug whose solubilizer is necessary for ad
Externí odkaz:
https://doaj.org/article/1d07b470fded4a229d3da3a0e74b5766
Autor:
Hiroya Shiba, Misaki Nishio, Mei Sawada, Mamiko Tamaki, Masataka Michigami, Shinya Nakai, Ikuhiko Nakase, Ikuo Fujii, Akikazu Matsumoto, Chie Kojima
Publikováno v:
Journal of Materials Chemistry B. 10:2463-2470
Although T cells play important roles in various immune reactions, there are only a few reports on delivery systems into T cells. Our previous study showed that carboxy-terminal phenylalanine (Phe)-modified polyamidoamine (PAMAM) dendrimers have both
Autor:
Yutaka Nishimoto, Misaki Nishio, Shu Nagashima, Kohei Nakajima, Takayuki Ohira, Shinya Nakai, Ikuhiko Nakase, Kei Higashikawa, Yuji Kuge, Akikazu Matsumoto, Mikako Ogawa, Chie Kojima
Publikováno v:
Polymers, Vol 12, Iss 7, p 1474 (2020)
Delivery systems to lymph node-resident T cells around tumor tissues are essential for cancer immunotherapy, in order to boost the immune responses. We previously reported that anionic dendrimers, such as carboxyl-, sulfonyl-, and phosphate-terminal
Externí odkaz:
https://doaj.org/article/b29f7bada2fd4514bf9fa0795c9c5090