Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chidi, Mestayer"'
Autor:
Roman L, Bogorad, Carine, Courtillot, Chidi, Mestayer, Sophie, Bernichtein, Lilya, Harutyunyan, Jean-Baptiste, Jomain, Anne, Bachelot, Frédérique, Kuttenn, Paul A, Kelly, Vincent, Goffin, Philippe, Touraine, S, Yacoub
Publikováno v:
Proceedings of the National Academy of Sciences. 105:14533-14538
There is currently no known genetic disease linked to prolactin (Prl) or its receptor (PrlR) in humans. Given the essential role of this hormonal system in breast physiology, we reasoned that genetic anomalies of Prl/PrlR genes may be related to the
Publikováno v:
The Prostate. 56:192-200
BACKGROUND In prostate cancer cell lines, androgen receptor (AR) coactivators modulate the transcriptional activity of AR. However, very little is known about their expression in normal prostate tissue and during progression to cancer. METHODS AR and
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 82:297-304
TGF beta can promote and/or suppress prostate tumor growth through multiple and opposing actions. Alterations of its expression, secretion, regulation or of the sensitivity of target cells can lead to a favorable environment for tumor development. To
Publikováno v:
The Prostate. 46:311-318
BACKGROUND Stromal–epithelial interactions play a critical role in prostate development, but the precise mechanisms are still unknown. Transforming growth factor-beta (TGFβ) could be a potential mediator of these interactions, but there is as yet
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 66:319-326
The regulation of the androgen receptor (AR) expression was studied using immunocytochemical and Western blot techniques on separate cultures of epithelial cells (PNT2) and fibroblasts of human prostate. In both cell types, immunocytochemistry reveal
Publikováno v:
The Prostate. 32:155-163
BACKGROUND Whereas the embryological development of the human prostate is clearly dependent on steroid 5 alpha-reductase (5 alpha-R) type 2 expression, the respective expression of the two known isoforms (types 1 and 2) of 5 alpha-R in the adult huma
Autor:
Frédérique Kuttenn, Chidi Mestayer, Isabelle Berthaut, Irène Mowszowicz, Françoise Wright, Pierre Mauvais-Jarvis
Publikováno v:
Andrologie. 4:71-77
Les tissus humains contiennent au moins deux isozymes de la 5α-reductase (5α-R), types 1 et 2 qui different par: leur localisation chromosomique, leur sensibilite aux inhibiteurs, leur expression tissulaire. La 5α-R2 est l’isozyme implique dans