Mice Lacking Desmocollin 1 Show Epidermal Fragility Accompanied by Barrier Defects and Abnormal Differentiation

Autor: Chidgey, Martyn, Brakebusch, Cord, Gustafsson, Erika, Cruchley, Alan, Hail, Chris, Kirk, Sarah, Merritt, Anita, North, Alison, Tselepis, Chris, Hewitt, Jane, Byrne, Carolyn, Fassler, Reinhard, Garrod, David

Publikováno v: The Journal of Cell Biology, 2001 Nov . 155(5), 821-832.

Externí odkaz: https://www.jstor.org/stable/1620908

Missense Mutations in Desmoplakin Plakin Repeat Domains Have Dramatic Effects on Domain Structure and Function

Autor: Mohammed, Fiyaz, Odintsova, Elena, Chidgey, Martyn

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 529, p 529 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 529

Plakin repeat domains (PRDs) are globular modules that mediate the interaction of plakin proteins with the intermediate filament (IF) cytoskeleton. These associations are vital for maintaining tissue integrity in cardiac muscle and epithelial tissues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472860b88d0385e5f9567155154dbb9b
https://www.mdpi.com/1422-0067/23/1/529

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Sequence-specific 1H, 13C and 15N backbone resonance assignments of the plakin repeat domain of human envoplakin

Autor: Jeeves, Mark, Fogl, Claudia, Al-Jassar, Caezar, Chidgey, Martyn, Overduin, Michael

Publikováno v: Biomolecular Nmr Assignments

The plakin repeat domain is a distinctive hallmark of the plakin superfamily of proteins, which are found within all epithelial tissues. Plakin repeat domains mediate the interactions of these proteins with the cell cytoskeleton and are critical for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fe0f369ce13fe06f92cac6056b6c5e4f
http://europepmc.org/articles/PMC4788679

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