Response to chemotherapy is not related to chromosome instability in synovial sarcoma

Autor: Chakiba, C., Lagarde, P., Pissaloux, D., Neuville, A., Brulard, C., Pérot, G., Coindre, J.M., Terrier, P., Ranchere-Vince, D., Ferrari, A., Collini, P., Suurmeijer, A.J.H., Blay, J.Y., Terrisse, S.A., Piperno-Neumann, S., Averous, G., Bui, B., Orbach, D., Italiano, A., Chibon, F. ^*

Publikováno v: In Annals of Oncology November 2014 25(11):2267-2271

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Chemotherapy in localized soft tissue sarcoma: will we soon have to treat grade 1 tumors? Update on CINSARC performances

Autor: Valentin, T., Lesluyes, T., Le Guellec, S., Chibon, F.

Publikováno v: In Annals of Oncology January 2019 30(1):153-155

The role of the anti-aging protein klotho in IGF-1 signaling and reticular calcium leak: impact on the chemosensitivity of dedifferentiated liposarcomas

Autor: Delcroix, V., Mauduit, O., Tessier, Nolwenn, Montillaud, A., Lesluyes, T., Ducret, T., Chibon, F., Van Coppenolle, Fabien, Ducreux, Sylvie, Vacher, P.

Publikováno v: Cancers
Cancers, MDPI, 2018, 10 (11), pp.1-24. ⟨10.3390/cancers10110439⟩
Cancers, Vol 10, Iss 11, p 439 (2018)
Volume 10
Issue 11
Cancers, MDPI, 2018, 10 (11), pp.24. ⟨10.3390/cancers10110439⟩
Cancers, MDPI, 2018, 10 (11), pp.24

By inhibiting Insulin-Like Growth Factor-1-Receptor (IGF-1R) signaling, Klotho (KL) acts like an aging- and tumor-suppressor. We investigated whether KL impacts the aggressiveness of liposarcomas, in which IGF-1R signaling is frequently upregulated.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dc5b595d3516f16913a08e8a0f505f35
https://hal.archives-ouvertes.fr/hal-02264349/document

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