Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Chiara Zucchelli"'
Autor:
Malisa Vittoria Mantonico, Federica De Leo, Giacomo Quilici, Liam Sean Colley, Francesco De Marchis, Massimo Crippa, Rosanna Mezzapelle, Tim Schulte, Chiara Zucchelli, Chiara Pastorello, Camilla Carmeno, Francesca Caprioglio, Stefano Ricagno, Gabriele Giachin, Michela Ghitti, Marco Emilio Bianchi, Giovanna Musco
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Chemokine heterodimers activate or dampen their cognate receptors during inflammation. The CXCL12 chemokine forms with the fully reduced (fr) alarmin HMGB1 a physiologically relevant heterocomplex (frHMGB1•CXCL12) that synergically promote
Externí odkaz:
https://doaj.org/article/d054899c802941a79cd558a8f7c91f5a
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 4, Pp 1009-1014 (2025)
PrPSc, a misfolded, aggregation-prone isoform of the cellular prion protein (PrPC), is the infectious prion agent responsible for fatal neurodegenerative diseases of humans and other mammals. PrPSc can adopt different pathogenic conformations (prion
Externí odkaz:
https://doaj.org/article/9ae986dae2444a55b8cc4a00ffb608de
Autor:
Antonio Masone, Chiara Zucchelli, Enrico Caruso, Giada Lavigna, Hasier Eraña, Gabriele Giachin, Laura Tapella, Liliana Comerio, Elena Restelli, Ilaria Raimondi, Saioa R. Elezgarai, Federica De Leo, Giacomo Quilici, Lorenzo Taiarol, Marvin Oldrati, Nuria L. Lorenzo, Sandra García-Martínez, Alfredo Cagnotto, Jacopo Lucchetti, Marco Gobbi, Ilaria Vanni, Romolo Nonno, Michele A. Di Bari, Mark D. Tully, Valentina Cecatiello, Giuseppe Ciossani, Sebastiano Pasqualato, Eelco Van Anken, Mario Salmona, Joaquín Castilla, Jesús R. Requena, Stefano Banfi, Giovanna Musco, Roberto Chiesa
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108223- (2023)
Externí odkaz:
https://doaj.org/article/b54cc5dafd374331865a0f0374b0327f
Autor:
Mario Saare, Uku Hämarik, Rainis Venta, Marina Panarina, Chiara Zucchelli, Maire Pihlap, Anu Remm, Kai Kisand, Urve Toots, Kaidi Möll, Riina Salupere, Giovanna Musco, Raivo Uibo, Pärt Peterson
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
The SP100 family members comprise a set of closely related genes on chromosome 2q37.1. The widely expressed SP100 and the leukocyte-specific proteins SP110 and SP140 have been associated with transcriptional regulation and various human diseases. Her
Externí odkaz:
https://doaj.org/article/65edfa692adb4cb58162b83a2777a992
Autor:
Giovanna Musco, Chiara Zucchelli, Giacomo Quilici, Giuseppe Filosa, Angela Bachi, Michela Ghitti, Simone Tamburri
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1863:456-465
Background Human Sp140 protein is a leukocyte-specific member of the speckled protein (Sp) family (Sp100, Sp110, Sp140, Sp140L), a class of multi-domain nuclear proteins involved in intrinsic immunity and transcriptional regulation. Sp140 regulates m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7ba2cf472dd017e161c250b9eb58b9
https://doi.org/10.1016/j.bbagen.2018.11.011
https://doi.org/10.1016/j.bbagen.2018.11.011
Autor:
Marco Bianchi, Giacomo Quilici, Alessandro Preti, Mario Tirone, Francesco De Marchis, Giovanna Musco, Rosanna Mezzapelle, Federica De Leo, Chiara Zucchelli, Alessandro Gori, Valeria Mannella, Maura Casalgrandi
Publikováno v:
EMBO Rep
EMBO reports
20 (2019): 1–13. doi:10.15252/embr.201947788
info:cnr-pdr/source/autori:De Leo F.; Quilici G.; Tirone M.; De Marchis F.; Mannella V.; Zucchelli C.; Preti A.; Gori A.; Casalgrandi M.; Mezzapelle R.; Bianchi M.E.; Musco G./titolo:Diflunisal targets the HMGB1%2FCXCL12 heterocomplex and blocks immune cell recruitment/doi:10.15252%2Fembr.201947788/rivista:EMBO reports (Print)/anno:2019/pagina_da:1/pagina_a:13/intervallo_pagine:1–13/volume:20
EMBO reports
20 (2019): 1–13. doi:10.15252/embr.201947788
info:cnr-pdr/source/autori:De Leo F.; Quilici G.; Tirone M.; De Marchis F.; Mannella V.; Zucchelli C.; Preti A.; Gori A.; Casalgrandi M.; Mezzapelle R.; Bianchi M.E.; Musco G./titolo:Diflunisal targets the HMGB1%2FCXCL12 heterocomplex and blocks immune cell recruitment/doi:10.15252%2Fembr.201947788/rivista:EMBO reports (Print)/anno:2019/pagina_da:1/pagina_a:13/intervallo_pagine:1–13/volume:20
Extracellular HMGB1 triggers inflammation following infection or injury and supports tumorigenesis in inflammation-related malignancies. HMGB1 has several redox states: reduced HMGB1 recruits inflammatory cells to injured tissues forming a heterocomp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af92ca5068b35ffc15cd1908594ef290
https://pubmed.ncbi.nlm.nih.gov/31418171
https://pubmed.ncbi.nlm.nih.gov/31418171
Autor:
Chiara, Zucchelli, Antonio, Masone, Caruso, Enrico, Ilaria, Vanni, Elena, Restelli, Alfredo, Cagnotto, Mario, Salmona, Romolo, Nonno, Requena, Jesus R., Banfi, Stefano, Gioanna, Musco, Roberto, Chiesa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3660::a4cbb0112980cf1f322f292f2640f971
http://hdl.handle.net/11383/2115546
http://hdl.handle.net/11383/2115546
Publikováno v:
Scientific Reports
PREP1 and PBX1 are homeodomain (HD) transcription factors that play crucial roles in embryonic development. Here, we present the first biophysical characterization of a PREP1 HD, and the NMR spectroscopic study of its DNA binding pocket. The data sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4204a47fe1c408c51a083f8d7e4c725d
Autor:
Angelo Corti, Massimo Lazzaro, Marco Barbariga, Andrea Spitaleri, Chiara Zucchelli, Flavio Curnis, Giovanna Musco, Giuseppe Magnani, Annapaola Andolfo, Massimo Alessio
Publikováno v:
Journal of Biological Chemistry. 289:3736-3748
Asparagine deamidation occurs spontaneously in proteins during aging; deamidation of Asn-Gly-Arg (NGR) sites can lead to the formation of isoAsp-Gly-Arg (isoDGR), a motif that can recognize the RGD-binding site of integrins. Ceruloplasmin (Cp), a fer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7474503fd14c567572d754ddc5c3519
https://doi.org/10.1074/jbc.m113.520981
https://doi.org/10.1074/jbc.m113.520981
Autor:
Claudia Asperti, Paola Di Matteo, Catia Traversari, Barbara Valentinis, Gian Paolo Rizzardi, Dan Zhou, Manuela Cota, Chiara Zucchelli, Simona Porcellini, Gianpiero Garau, Nilla Roberta Avanzi, Massimo Degano, Giovanna Musco
Publikováno v:
'International Journal of Molecular Sciences ', vol: 20, pages: 4511-1-4511-22 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4511 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 18
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4511 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 18
NGR-hTNF is a therapeutic agent for a solid tumor that specifically targets angiogenic tumor blood vessels, through the NGR motif. Its activity has been assessed in several clinical studies encompassing tumors of different histological types. The dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6c511677049392198a2073d337f538
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:53926
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:53926