Tolerability of vortioxetine compared to selective serotonin reuptake inhibitors in older adults with major depressive disorder (VESPA): a randomised, assessor-blinded and statistician-blinded, multicentre, superiority trialResearch in context

Autor: Giovanni Ostuzzi, Chiara Gastaldon, Mauro Tettamanti, Massimo Cartabia, Igor Monti, Andrea Aguglia, Eugenio Aguglia, Francesco Bartoli, Camilla Callegari, Andrea Canozzi, Elvira Anna Carbone, Giuseppe Carrà, Rosangela Caruso, Simone Cavallotti, Stefania Chiappini, Fabrizio Colasante, Beatrice Compri, Armando D'Agostino, Pasquale De Fazio, Renato de Filippis, Matteo Gari, Marta Ielmini, Gianmarco Ingrosso, Silvia Mammarella, Giovanni Martinotti, Alessandro Rodolico, Rita Roncone, Enrico Sterzi, Lorenzo Tarsitani, Elisa Tiberto, Liliana Todini, Francesco Amaddeo, Barbara D'Avanzo, Angelo Barbato, Corrado Barbui, Maria Chiara Alessi, Gabriele Avincola, Bianca Bachi, Gianna Bernasconi, Andrea Birgillito, Emanuele Bisso, Stefano Bonora, Angela Calabrese, Tommaso Callovini, Aurelia Canestro, Salvo Canonico, Chiara Alessandro Capogrosso, Elvira Carbone, Doriana Carosielli, Ivano Caselli, Daniele Cavaleri, Clara Cavallotto, Marco Cesca, Cecilia Chiarenza, Riccardo Matteo Cioni, Sara Coloccini, Marco Cruciata, Claudia Cumerlato, Renato De Filippis, Manuela De Palma, Sasha Del Vecchio, Bianca Della Rocca, Chiara Di Natale, Ettore D'Onofrio, Irene Espa, Giulia Fior, Marta Gancitano, Barbara Giordano, Laura Giusti, Luigi Grassi, Pierluca Guzzi, Celeste Isella, Annamaria Lax, Leonardo Marano, Federico Marconi, Marco Marella, Alessia Metelli, Giulia Michencig, Andrea Miuli, Alessandro Moncada, Pietro Morello, Federico Moretti, Marco Morreale, Alessio Mosca, Christian Nasti, Michela Nosé, Filippo Ogheri, Margherita Oresti, Alessandra Ornaghi, Dario Palpella, Corinna Pancheri, Davide Papola, Silvia Passeri, Mauro Pettorusso, Susanna Piacenti, Irene Pinucci, Valentina Pugliese, Marianna Purgato, Marianna Rania, Federica Robbi, Samantha Romito, Barbara Ronchi, Valentina Roselli, Cristina Segura-Garcia, Maria Salvina Signorelli, Gabriele Simonelli, Antonella Sociali, Serena Sturiale, Antonio Tambelli, Beatrice Todesco, Alice Trabucco, Giulia Turrini, Veronica Villa, Federico Wiedenmann, Luca Zambuto, Elisa Zanini, Chiara Zannini, Luigi Zerbinati

Publikováno v: EClinicalMedicine, Vol 69, Iss , Pp 102491- (2024)

Summary: Background: Major depressive disorder (MDD) is prevalent and disabling among older adults. Standing on its tolerability profile, vortioxetine might be a promising alternative to selective serotonin reuptake inhibitors (SSRIs) in such a vulne

Externí odkaz: https://doaj.org/article/b6d9532a29514d6885cce2880822f39b

Protective effects of exosomes derived from lyophilized porcine liver against acetaminophen damage on HepG2 cells

Autor: Riccardo Tassinari, Claudia Cavallini, Elena Olivi, Valentina Taglioli, Chiara Zannini, Orlando Ferroni, Carlo Ventura

Publikováno v: BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-14 (2021)

Abstract Background Recently, extracellular vesicles have come to the fore following their emerging role in cell communication, thanks to their ability to reach cells into the human body without dissipating their cargo, transferring biological active

Externí odkaz: https://doaj.org/article/2b7d987f51904bfaab126e2dcf92691c

Restoring In Vivo-Like Membrane Lipidomics Promotes Exosome Trophic Behavior from Human Placental Mesenchymal Stromal/Stem Cells

Autor: Claudia Cavallini, Chiara Zannini, Elena Olivi, Riccardo Tassinari, Valentina Taglioli, Martina Rossi, Paola Poggi, Alexandros Chatgilialoglu, Giuliana Simonazzi, Francesco Alviano, Laura Bonsi, Carlo Ventura

Publikováno v: Cell Transplantation, Vol 27 (2018)

Human mesenchymal stem cells (hMSCs) are an effective tool in regenerative medicine notably for their intrinsic plentiful paracrine activity rather than differentiating properties. The hMSC secretome includes a wide spectrum of regulatory and trophic

Externí odkaz: https://doaj.org/article/094587e8bd4c4c688ede20af5ffe6dad

Characterization of the Tissue and Stromal Cell Components of Micro-Superficial Enhanced Fluid Fat Injection (Micro-SEFFI) for Facial Aging Treatment

Autor: Pierluigi Reschiglian, Silvia Zia, Laura Bonsi, Alessandro Gennai, Martina Rossi, Francesco Alviano, Ilaria Vigliotta, Barbara Roda, Andrea Zattoni, Chiara Zannini

Background New microfat preparations provide material suitable for use as a regenerative filler for different facial areas. To support the development of new robust techniques for regenerative purposes, the cellular content of the sample should be co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61697e2f41ed2c52dd084fe292424e7d
http://hdl.handle.net/11585/810120

Intracrine Endorphinergic Systems in Modulation of Myocardial Differentiation

Autor: Elena Olivi, Federica Facchin, Riccardo Tassinari, Eva Bianconi, Margherita Maioli, Valentina Taglioli, Silvia Canaider, Carlo Ventura, Claudia Cavallini, Chiara Zannini

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5175 (2019)

A wide variety of peptides not only interact with the cell surface, but govern complex signaling from inside the cell. This has been referred to as an “intracrine” action, and the orchestrating molecules as “intracrines”. Here, we review the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05183b1befd5f2b7e7e323737ab0b3ab
http://europepmc.org/articles/PMC6829321