Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chiara Victor"'
Autor:
Marian Kalocsay, Matthew J. Berberich, Robert A. Everley, Maulik K. Nariya, Mirra Chung, Benjamin Gaudio, Chiara Victor, Gary A. Bradshaw, Robyn J. Eisert, Marc Hafner, Peter K. Sorger, Caitlin E. Mills, Kartik Subramanian
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-9 (2023)
Abstract We performed quantitative proteomics on 60 human-derived breast cancer cell line models to a depth of ~13,000 proteins. The resulting high-throughput datasets were assessed for quality and reproducibility. We used the datasets to identify an
Externí odkaz:
https://doaj.org/article/d36f69bd2a254d5687bc8e7f98e95fc1
Autor:
Caitlin E. Mills, Kartik Subramanian, Marc Hafner, Mario Niepel, Luca Gerosa, Mirra Chung, Chiara Victor, Benjamin Gaudio, Clarence Yapp, Ajit J. Nirmal, Nicholas Clark, Peter K. Sorger
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
It is currently difficult to perform accurate single-cell assays in 384-well plates. Here the authors report Dye Drop which uses sequential density displacement and microscopy for multi-step assays on cells, and use this to collect single-cell dose-r
Externí odkaz:
https://doaj.org/article/fd5702d7273c4618abdb7be6d446e8fd
Autor:
Caitlin Mills, Kartik Subramanian, Marc Hafner, Mario Niepel, Luca Gerosa, Mirra Chung, Chiara Victor, Benjamin Gaudio, Clarence Yapp, Ajit Johnson Nirmal, Nicholas Clark, Peter Sorger
High-throughput measurement of cells perturbed using libraries of small molecules, gene knockouts, or different microenvironmental factors is a key step in functional genomics and pre-clinical drug discovery. However, it remains difficult to perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca4c87a1f1309ca57bb83ba37f2ab55c
https://doi.org/10.21203/rs.3.rs-1813095/v1
https://doi.org/10.21203/rs.3.rs-1813095/v1
Autor:
Nathanael S. Gray, Tinghu Zhang, Caitlin E. Mills, John M. Hatcher, Peter K. Sorger, Eric S. Fischer, Nicholas Kwiatkowski, Jie Jiang, Chiara Victor, Mingxing Teng, Katherine A. Donovan, Zhixiang He
Publikováno v:
Angew Chem Int Ed Engl
Cyclin-dependent kinase 2 (CDK2) is a potential therapeutic target for the treatment of cancer. Development of CDK2 inhibitors has been extremely challenging as its ATP-binding site shares high similarity with CDK1, a related kinase whose inhibition
Autor:
Chiara Victor, Luca Gerosa, Ben Gaudio, Mario Niepel, Kartik Subramanian, Marc Hafner, Peter K. Sorger, Mirra Chung, Clarence Yapp, Caitlin E. Mills
High-throughput measurement of cells perturbed using libraries of small molecules, gene knockouts, or different microenvironmental factors is a key step in functional genomics and pre-clinical drug discovery. However, it remains difficult to perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5c359da92cf23f9d735736ac8beec71
https://doi.org/10.1101/2021.08.27.457854
https://doi.org/10.1101/2021.08.27.457854
Autor:
Caitlin E. Mills, Kartik Subramanian, Marc Hafner, Mario Niepel, Luca Gerosa, Mirra Chung, Chiara Victor, Benjamin Gaudio, Clarence Yapp, Ajit J. Nirmal, Nicholas Clark, Peter K. Sorger
Publikováno v:
Nature communications. 13(1)
High-throughput measurement of cells perturbed using libraries of small molecules, gene knockouts, or different microenvironmental factors is a key step in functional genomics and pre-clinical drug discovery. However, it remains difficult to perform
Autor:
Ben Gaudio, Peter K. Sorger, Robert A. Everley, Caitlin E. Mills, Marian Kalocsay, Matthew J. Berberich, Chiara Victor, Marc Hafner, Mirra Chung, Gary A. Bradshaw, Kartik Subramanian, Maulik K. Nariya
We performed quantitative proteomics on 60 human-derived breast cancer cell lines to a depth of ~13,000 proteins. The resulting high-throughput datasets were assessed for quality and reproducibility. We used the datasets to identify and characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40478409793819e8d4dca2afaaacb420
https://doi.org/10.1101/2020.12.15.422823
https://doi.org/10.1101/2020.12.15.422823