Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chiara V. Ragni"'
Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth
Autor:
Chiara V. Ragni, Nicolas Diguet, Jean-François Le Garrec, Marta Novotova, Tatiana P. Resende, Sorin Pop, Nicolas Charon, Laurent Guillemot, Lisa Kitasato, Caroline Badouel, Alexandre Dufour, Jean-Christophe Olivo-Marin, Alain Trouvé, Helen McNeill, Sigolène M Meilhac
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Growth of the mammalian heart is controlled by Hippo signalling but how this is regulated is unclear. Here, the authors show that Fat4 (an atypical cadherin) acts upstream of Hippo signalling and Fat4 mutant mice have thicker myocardium, which is med
Externí odkaz:
https://doaj.org/article/e8f4fd524d4c427fa1e8c9b37e7353f2
Quantitative analysis of polarity in 3D reveals local cell coordination in the embryonic mouse heart
Autor:
Jean-Christophe Olivo-Marin, Chiara V. Ragni, Sigolène M. Meilhac, Jean-François Le Garrec, Margaret Buckingham, Sorin Pop, Alexandre Dufour
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2013, 140 (2), pp.395-404. ⟨10.1242/dev.087940⟩
Development; Vol 140
Development (Cambridge, England), 2013, 140 (2), pp.395-404. ⟨10.1242/dev.087940⟩
Development (Cambridge, England), Company of Biologists, 2013, 140 (2), pp.395-404. ⟨10.1242/dev.087940⟩
Development; Vol 140
Development (Cambridge, England), 2013, 140 (2), pp.395-404. ⟨10.1242/dev.087940⟩
International audience; Anisotropies that underlie organ morphogenesis have been quantified in 2D, taking advantage of a reference axis. However, morphogenesis is a 3D process and it remains a challenge to analyze cell polarities in 3D. Here, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c777566624854cd40fcec2d1c11162dc
https://doi.org/10.1242/dev.087940
https://doi.org/10.1242/dev.087940
Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth
Autor:
Chiara V. Ragni, Jean-François Le Garrec, Jean-Christophe Olivo-Marin, Laurent Guillemot, Tatiana P. Resende, Alain Trouvé, Sigolène M. Meilhac, Helen McNeill, Lisa Kitasato, Nicolas Diguet, Marta Novotova, Nicolas Charon, Alexandre Dufour, Sorin Pop, Caroline Badouel
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8, pp.14582. ⟨10.1038/ncomms14582⟩
Nature Communications, 2017, 8, pp.14582. ⟨10.1038/ncomms14582⟩
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications, Nature Publishing Group, 2017, 8, pp.14582. ⟨10.1038/ncomms14582⟩
Nature Communications, 2017, 8, pp.14582. ⟨10.1038/ncomms14582⟩
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Although in flies the atypical cadherin Fat is an upstream regulator of Hippo signalling, the closest mammalian homologue, Fat4, has been shown to regulate tissue polarity rather than growth. Here we show in the mouse heart that Fat4 modulates Hippo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9441aa6c8d4bb62d6d6c7c9902f5bff3
https://pubmed.ncbi.nlm.nih.gov/28239148
https://pubmed.ncbi.nlm.nih.gov/28239148
Autor:
Sorin Pop, Chiara V. Ragni, Alexandre Dufour, Sigolène M. Meilhac, Clémire Cimper, Jean-François Le Garrec, Jean-Christophe Olivo-Marin
Publikováno v:
Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2013, 29 (6), pp.772-9. ⟨10.1093/bioinformatics/btt027⟩
Bioinformatics, 2013, 29 (6), pp.772-9. ⟨10.1093/bioinformatics/btt027⟩
Bioinformatics, Oxford University Press (OUP), 2013, 29 (6), pp.772-9. ⟨10.1093/bioinformatics/btt027⟩
Bioinformatics, 2013, 29 (6), pp.772-9. ⟨10.1093/bioinformatics/btt027⟩
Motivation: In developmental biology, quantitative tools to extract features from fluorescence microscopy images are becoming essential to characterize organ morphogenesis at the cellular level. However, automated image analysis in this context is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d39495d7b91c4b991221d254a58dcd
https://hal-pasteur.archives-ouvertes.fr/pasteur-01572064
https://hal-pasteur.archives-ouvertes.fr/pasteur-01572064
