Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chiara Tyndall"'
Publikováno v:
Journal of Molecular Biology. 237:266-274
The prr locus was originally described as coding a ribonuclease that is activated after phage T4 infection to cut within the anticodon of a specific tRNA, inactivating protein synthesis and thus blocking phage development. Wild-type T4 phage has two
Publikováno v:
Journal of Molecular Biology. 226:289-299
We have analysed binding sites of nuclear protein factors to a CpG island (HTF9), which contains the promoter for a pair of overlapping, divergently-transcribed “housekeeping” genes. Using DNaseI protection assays with extracts from a range of di
Publikováno v:
Molecular microbiology. 23(4)
EcoR124l, EcoDXXl and Ecoprrl are the known members of the type IC family of DNA restriction and modification systems. The first three are carried on large, conjugative plasmids, while Ecoprrl is chromosomally encoded. The enzymes are coded by three
Publikováno v:
Nucleic Acids Research. 9:6305-6322
We have localized with respect to the genomic DNA sequence the capped 5'-termini of polyoma virus late region mRNAs. A minimum of fifteen different purine termini were found within a 94 base pair region (66.36 to 68.12 map units, nt 5075-5168) immedi
Publikováno v:
Nature. 312:242-246
Sequences which activate polyoma virus DNA replication are located within a region that also includes the transcriptional enhancer. We demonstrate a cis involvement of enhancers in DNA replication by showing that this region can be replaced by other
Publikováno v:
Nucleic Acids Research. 9:6231-6250
Deletion mutants within the Py DNA region between the replication origin and the beginning of late protein coding sequences have been constructed and analysed for viability, early gene expression and viral DNA replication. Assay of replicative compet
Publikováno v:
Nucleic acids research. 10(24)
Transcriptional "enhancers" have been identified in both the monkey virus SV40 and in the mouse polyoma virus. Here we report that these enhancers show a cell type preference. This was done, (i) by assaying for T antigen expression and viral DNA repl
Publikováno v:
Nucleic acids research. 9(21)
In order to map the high affinity binding site for the viral large-T protein on polyoma virus DNA, we have developed an assay which does not require purified protein. It is based on the specific elution of the large-T ATPase activity from calf thymus