Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chiara Simone Middel"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Zebrafish (Danio rerio) have been established in recent years as a model organism to study Diabetic Retinopathy (DR). Loss of endothelial cells and pericytes is an early hallmark sign of developing DR in the mammalian retina. However, mor
Externí odkaz:
https://doaj.org/article/87c20a644e4b4b2da99c83d28f8e16d8
Autor:
Christoph Tobias Tabler, Elisabeth Lodd, Katrin Bennewitz, Chiara Simone Middel, Vanessa Erben, Hannes Ott, Tanja Poth, Thomas Fleming, Jakob Morgenstern, Ingrid Hausser, Carsten Sticht, Gernot Poschet, Julia Szendroedi, Peter Paul Nawroth, Jens Kroll
Publikováno v:
Redox Biology, Vol 59, Iss , Pp 102576- (2023)
Glyoxalase 2 is the second enzyme of the glyoxalase system, catalyzing the detoxification of methylglyoxal to d-lactate via SD-Lactoylglutathione. Recent in vitro studies have suggested Glo2 as a regulator of glycolysis, but if Glo2 regulates glucose
Externí odkaz:
https://doaj.org/article/8ec9121e06394c43ad839a73926f3863
Autor:
David Philipp Wohlfart, Bowen Lou, Chiara Simone Middel, Jakob Morgenstern, Thomas Fleming, Carsten Sticht, Ingrid Hausser, Rüdiger Hell, Hans-Peter Hammes, Julia Szendrödi, Peter Paul Nawroth, Jens Kroll
Publikováno v:
Redox Biology, Vol 50, Iss , Pp 102249- (2022)
Reactive carbonyl species (RCS) are spontaneously formed in the metabolism and modify and impair the function of DNA, proteins and lipids leading to several organ complications. In zebrafish, knockout of the RCS detoxifying enzymes glyoxalase 1 (Glo
Externí odkaz:
https://doaj.org/article/3d1cdcad30e44060993f91c00777083e
Publikováno v:
Cells, Vol 10, Iss 6, p 1313 (2021)
Diabetic retinopathy is one of the most important microvascular complications associated with diabetes mellitus, and a leading cause of vision loss or blindness worldwide. Hyperglycaemic conditions disrupt microvascular integrity at the level of the
Externí odkaz:
https://doaj.org/article/b2a08480de73400882caec53b261b0f4
Autor:
Christoph Tobias Tabler, Elisabeth Lodd, Katrin Bennewitz, Chiara Simone Middel, Vanessa Erben, Hannes Ott, Tanja Poth, Thomas Fleming, Jakob Morgenstern, Ingrid Hausser, Carsten Sticht, Gernot Poschet, Julia Szendroedi, Peter Paul Nawroth, Jens Kroll
Publikováno v:
Redox biology. 59
Glyoxalase 2 is the second enzyme of the glyoxalase system, catalyzing the detoxification of methylglyoxal to d-lactate via SD-Lactoylglutathione. Recent in vitro studies have suggested Glo2 as a regulator of glycolysis, but if Glo2 regulates glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0935b86fc9934284613cbeef929daf6
https://pubmed.ncbi.nlm.nih.gov/36535130
https://pubmed.ncbi.nlm.nih.gov/36535130
Publikováno v:
Hand in Hand zum Ziel – einfach.besser.messbar www.diabeteskongress.de.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d60833d8d99dc92193e677c60088a3a9
https://doi.org/10.1055/s-0042-1746379
https://doi.org/10.1055/s-0042-1746379
Autor:
David Philipp, Wohlfart, Bowen, Lou, Chiara Simone, Middel, Jakob, Morgenstern, Thomas, Fleming, Carsten, Sticht, Ingrid, Hausser, Rüdiger, Hell, Hans-Peter, Hammes, Julia, Szendrödi, Peter Paul, Nawroth, Jens, Kroll
Publikováno v:
Redox biology. 50
Reactive carbonyl species (RCS) are spontaneously formed in the metabolism and modify and impair the function of DNA, proteins and lipids leading to several organ complications. In zebrafish, knockout of the RCS detoxifying enzymes glyoxalase 1 (Glo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb1d7bd15ba09e0392845f2eccd7ea8d
https://pubmed.ncbi.nlm.nih.gov/35114580
https://pubmed.ncbi.nlm.nih.gov/35114580
Publikováno v:
Cells
Cells, Vol 10, Iss 1313, p 1313 (2021)
Cells, Vol 10, Iss 1313, p 1313 (2021)
Diabetic retinopathy is one of the most important microvascular complications associated with diabetes mellitus, and a leading cause of vision loss or blindness worldwide. Hyperglycaemic conditions disrupt microvascular integrity at the level of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838ab7d6849e83b5c1c1409307041c07
https://pubmed.ncbi.nlm.nih.gov/34070439
https://pubmed.ncbi.nlm.nih.gov/34070439