Výsledky vyhledávání - "Chiara Schifano"

Akademický článek

Immune tolerance induction by nonmyeloablative haploidentical HSCT combining T-cell depletion and posttransplant cyclophosphamide

Autor: Franco Aversa, Esther Bachar-Lustig, Noga Or-Geva, Lucia Prezioso, Sabrina Bonomini, Ilenia Manfra, Alessandro Monti, Chiara Schifano, Yael Zlotnikov-Klionsky, Massimo F. Martelli, Gabriella Sammarelli, Maria Sassi, Maurizio Soli, Silvia Giuliodori, Magda Benecchi, Nicola Giuliani, Frank Lohr, Silvia Pratissoli, Yair Reisner

Publikováno v: Blood Advances, Vol 1, Iss 24, Pp 2166-2175 (2017)

Abstract: The establishment of safe approaches to attain durable donor-type chimerism and immune tolerance toward donor antigens represents a major challenge in transplantation biology. Haploidentical hematopoietic stem cell transplantation (HSCT) is

Externí odkaz: https://doaj.org/article/0237ce04ba7441e2b3c4ff122d4df453

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Expression of CD38 in myeloma bone niche: A rational basis for the use of anti-CD38 immunotherapy to inhibit osteoclast formation

Autor: Alberto L. Horenstein, Federica Costa, Eugenia Martella, Fabio Malavasi, Sabrina Bonomini, Denise Toscani, Chiara Schifano, Marina Bolzoni, Fabrizio Accardi, Nicoletta Campanini, Franco Aversa, Nicola Giuliani, Cristina Mancini, Rosanna Vescovini, Valeria Quarona, Antonella Chillemi, Valentina Marchica

Publikováno v: Oncotarget

// Federica Costa 1, * , Denise Toscani 1, * , Antonella Chillemi 2 , Valeria Quarona 2 , Marina Bolzoni 1 , Valentina Marchica 1, 6 , Rosanna Vescovini 3 , Cristina Mancini 4 , Eugenia Martella 4 , Nicoletta Campanini 4 , Chiara Schifano 5 , Sabrina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e418d5b75990a1d1ae8546f670812771
http://europepmc.org/articles/PMC5593586

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Haploidentical hematopoietic stem cell transplantation in adults using the αβTCR/CD19-based depletion of G-CSF-mobilized peripheral blood progenitor cells

Publikováno v: Bone marrow transplantation. 54(Suppl 2)

In patients with hematological malignancies at high risk for relapse, a mismatched hematopoietic stem cells transplants can be offered with no undue delay between decision-making and transplantation as virtually all patients have a full-haplotype mis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f182025c3f51d31526b79ba5c7cca119
https://pubmed.ncbi.nlm.nih.gov/32286504

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Cutaneous localization in multiple myeloma in the context of bortezomib-based treatment: how do myeloma cells escape from the bone marrow to the skin?

Autor: Cristina Mancini, Marina Bolzoni, Antonino Neri, Katia Todoerti, Valentina Marchica, Chiara Schifano, Magda Marcatti, Fabrizio Accardi, Nicola Giuliani, Maurilio Ponzoni, Paola Storti, Franco Aversa, Gabriella Sammarelli, Benedetta Dalla Palma, Eugenia Martella, Sabrina Bonomini

Publikováno v: International Journal of Hematology. 105:104-108

The skin is a possible site of extramedullary localization in multiple myeloma (MM) patients; however, the mechanisms involved in this process are poorly understood. We describe the case of a refractory MM patient who developed a cutaneous localizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950da03f50ea3e41682ecef6ce15debc
https://doi.org/10.1007/s12185-016-2104-1

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Transplantation of T Cell Depleted Haploidentical HSCT Following Non-Myeloablative (NMA) Conditioning: Combining the Power of Megadose Transplants with Post Transplant Cyclophosphamide (PTCY)

Autor: Chiara Schifano, Ilenia Manfra, Yair Reisner, Sabrina Bonomini, Yael Zlotnikov Klionsky, Lucia Prezioso, Alessandro Monti, Esther Bachar-Lustig, Federica Galaverna, Noga Or Geva, Franco Aversa

Publikováno v: Blood. 128:5765-5765

The use of PTCY is associated with reduced risk for GVHD in T cell replete NMA haplo-human stem cell transplants (HSCT); however, this intervention is still not sufficiently safe to justify treatment of non-malignant diseases or as a platform for org

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ae0c05c5a1529ac4c49a3c0bb61734d
https://doi.org/10.1182/blood.v128.22.5765.5765

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Oncolytic Virotherapy in Multiple Myeloma: A Possible Alternative Role of Bovine Viruses

Autor: Marina Bolzoni, Federica Costa, Alfonso Rosamilia, Giulia Tebaldi, Chiara Schifano, Francesco Piazza, Daniela Guasco, Franco Aversa, Sabrina Bonomini, Nicola Giuliani, Paola Storti, Gaetano Donofrio, Rosanna Vescovini, Valentina Marchica, Fabrizio Accardi

Publikováno v: Blood. 128:2093-2093

Multiple Myeloma (MM) is a plasma cell malignancy characterized by the tight dependence to the bone marrow (BM) microenvironment that supports MM cells survival. Despite significant therapeutic progress in the recent years with the introduction of se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90b28acdfd1c32f7e481c59af0b3a2e7
https://doi.org/10.1182/blood.v128.22.2093.2093

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Haploidentical Stem Cell Transplantation After Negative Depletion Of T Cells Expressing The αβ Chain Of The T-Cell Receptor (TCR) For Adults With Hematological Malignancies

Autor: Cecilia Caramatti, Chiara Schifano, Gabriella Sammarelli, Luisa Craviotto, Elena Masselli, Franco Aversa, Elena Rossetti, Chiara Lambertini, Sabrina Bonomini, Giannalisa Todaro, Maria Sassi, Alessandro Monti, Lucia Prezioso

Publikováno v: Blood. 122:4609-4609

Introduction For many years, T cell depletion (TCD) of hematopoietic stem cells (HSCs) has been based on either positive or negative selection of mobilised peripheral blood cells (PBPCs). After CD34+ cell selection, the T cell repertoire is very narr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::224d8aa31250cc988b88dcc9f0c0b8a9
https://doi.org/10.1182/blood.v122.21.4609.4609

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