Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Chiara Recchi"'
Autor:
James R. Birtley, Mohammad Alomary, Elisa Zanini, Jane Antony, Zachary Maben, Grant C. Weaver, Claudia Von Arx, Manuela Mura, Aline T. Marinho, Haonan Lu, Eloise V. N. Morecroft, Evdoxia Karali, Naomi E. Chayen, Edward W. Tate, Mollie Jurewicz, Lawrence J. Stern, Chiara Recchi, Hani Gabra
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
OPCML is a tumour suppressor gene that is epigenetically silenced in ovarian cancer and is somatically mutated in various cancers. Here, the authors solve the X-ray crystal structure of OPCML and model clinically relevant mutations that could contrib
Externí odkaz:
https://doaj.org/article/0d39746c3dc44914b53cf2c2f0ee8062
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2019)
Objective: Apolipoprotein A1 (ApoA1) is remarkably decreased in serum and ovarian tissues of ovarian cancer patients. ApoA1 and ApoA1 mimetic peptides can sequestrate pro-inflammatory phospholipids, some of which are known to activate a variety of on
Externí odkaz:
https://doaj.org/article/1f1838e9a01b4dea950aa1be73391fd2
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148719 (2016)
Externí odkaz:
https://doaj.org/article/c1e40d488c8c4e0cace48d683e54763a
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102851 (2014)
The mechanism(s) by which Rab GTPases are specifically recruited to distinct intracellular membranes remains elusive. Here we used Rab27a localisation onto melanosomes as a model to investigate Rab targeting. We identified the α1 subunit of Na+,K+-A
Externí odkaz:
https://doaj.org/article/32989161d29149d79da37d5e6cf09ec4
Autor:
Suffwan Eltom, Nicole Dale, Kristof R G Raemdonck, Christopher S Stevenson, Robert J Snelgrove, Pradeep K Sacitharan, Chiara Recchi, Silene Wavre-Shapton, Daniel F McAuley, Cecilia O'Kane, Maria G Belvisi, Mark A Birrell
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e101087 (2014)
Infection-related exacerbations of respiratory diseases are a major health concern; thus understanding the mechanisms driving them is of paramount importance. Despite distinct inflammatory profiles and pathological differences, asthma and COPD share
Externí odkaz:
https://doaj.org/article/b6fee8ec794c40ebb8be32da0f861af9
Autor:
Hani Gabra, Chiara Recchi, Justin Stebbing, Mona El-Bahrawy, Sebastian Vaughan, Arthur B. McKie, Imoh S. Okon, Evdoxia Karali, Jane Antony, Louay S. Louis, Elisa Zanini
Opioid-binding protein/cell adhesion molecule-like (OPCML) is a tumor-suppressor gene that is frequently inactivated in ovarian cancer and many other cancers by somatic methylation. We have previously shown that OPCML exerts its suppressor function b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80f95190db02e253f295bd69d63e1ce
https://doi.org/10.1158/1535-7163.c.6538779.v1
https://doi.org/10.1158/1535-7163.c.6538779.v1
Autor:
Hani Gabra, Chiara Recchi, Justin Stebbing, Mona El-Bahrawy, Sebastian Vaughan, Arthur B. McKie, Imoh S. Okon, Evdoxia Karali, Jane Antony, Louay S. Louis, Elisa Zanini
Supplementary figures legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2285bdb99dbc833d66ee3e62c6eb5d52
https://doi.org/10.1158/1535-7163.22507752
https://doi.org/10.1158/1535-7163.22507752
Autor:
Hani Gabra, Chiara Recchi, Justin Stebbing, Mona El-Bahrawy, Sebastian Vaughan, Arthur B. McKie, Imoh S. Okon, Evdoxia Karali, Jane Antony, Louay S. Louis, Elisa Zanini
Schematic view of the constructs used in the mammalian 2-hybrid assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a73efad0c312e3408e71023cccf696ef
https://doi.org/10.1158/1535-7163.22507770
https://doi.org/10.1158/1535-7163.22507770
Autor:
Clotilde Théry, Matias Ostrowski, Miguel C. Seabra, Luis F. Moita, Chiara Recchi, Fabien Reyal, Sophie Krumeich, Angélique Bobrie
PDF file - 158K, Involvement of the immune system in differential growth of TS/A, 4T1, and their sh27a-expressing counterparts; A-Examples of FACS stainings and cytospin analysis of CD11b, CD11c, Ly6C and Ly6G in spleens of tumor-bearing mice. B, C-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615ddf3f9635326b0bd5c99ecc3e38eb
https://doi.org/10.1158/0008-5472.22393865.v1
https://doi.org/10.1158/0008-5472.22393865.v1
Autor:
Clotilde Théry, Matias Ostrowski, Miguel C. Seabra, Luis F. Moita, Chiara Recchi, Fabien Reyal, Sophie Krumeich, Angélique Bobrie
PDF file - 77K, Metastasis formation after i.v. injection and in vitro growth of 4T1; Metastasis formation by 4T1 after i.v. injection is decreased (A), whereas growth of 4T1 tumors in vitro is not affected (B) by Rab27a inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012cc8de43c6df9085ae2d06b6119cb8
https://doi.org/10.1158/0008-5472.22393868.v1
https://doi.org/10.1158/0008-5472.22393868.v1