Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Chiara Pighi"'
Autor:
Elena Morrocchi, Giuseppe R. Pascucci, Nicola Cotugno, Chiara Pighi, Sara Dominguez-Rodriguez, Maria Raffaella Petrara, Alfredo Tagarro, Louise Kuhn, Mark F. Cotton, Kennedy Otwombe, Maria G. Lain, Paula Vaz, Shaun L. Barnabas, Moira J. Spyer, Elisa Lopez, Sheila Fernández-Luis, Tacilta Nhampossa, Almoustapha I. Maiga, Oumar Dolo, Anita De Rossi, Pablo Rojo, Carlo Giaquinto, Mathias Lichterfeld, Avy Violari, Theresa Smit, Osee Behuhuma, Nigel Klein, Lesley De Armas, Savita Pahwa, Paolo Rossi, Paolo Palma, EPIICAL consortium
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract In this work our aim was to identify early biomarkers in plasma samples associated with mortality in children with perinatal HIV treated early in life, to potentially inform early intervention targeting this vulnerable group. 20/215 children
Externí odkaz:
https://doaj.org/article/286d2b323b6a46dda53e87d76b376c7c
Autor:
Chiara Pighi, Arianna Rotili, Maia De Luca, Sara Chiurchiù, Francesca Ippolita Calò Carducci, Chiara Rossetti, Loredana Cifaldi, Roberto Bei, Leonardo Caforio, Stefania Bernardi, Paolo Palma, Donato Amodio
Publikováno v:
Viruses, Vol 16, Iss 5, p 780 (2024)
Human cytomegalovirus (CMV) is a common herpesvirus causing lifelong latent infection in most people and is a primary cause of congenital infection worldwide. Given the role of NK cells in the materno-fetal barrier, we investigated peripheral blood N
Externí odkaz:
https://doaj.org/article/d5522cc3bfd44bee993ef0c312c97f62
Autor:
Sara Petillo, Cristina Capuano, Rosa Molfetta, Cinzia Fionda, Abdelilah Mekhloufi, Chiara Pighi, Fabrizio Antonangeli, Alessandra Zingoni, Alessandra Soriani, Maria Teresa Petrucci, Ricciarda Galandrini, Rossella Paolini, Angela Santoni, Marco Cippitelli
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-13 (2021)
Abstract Multiple Myeloma (MM) is an incurable hematologic malignancy of terminally differentiated plasma cells (PCs), where immune interactions play a key role in the control of cancer cell growth and survival. In particular, MM is characterized by
Externí odkaz:
https://doaj.org/article/027a95b214af4c66bd8400071bbc0d06
Autor:
Chiara Focaccetti, Monica Benvenuto, Chiara Pighi, Alessandra Vitelli, Federico Napolitano, Nicola Cotugno, Doriana Fruci, Paolo Palma, Paolo Rossi, Roberto Bei, Loredana Cifaldi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adoptive transfer of engineered NK cells, one of clinical approaches to fight cancer, is gaining great interest in the last decade. However, the development of new strategies is needed to improve clinical efficacy and safety of NK cell-based immunoth
Externí odkaz:
https://doaj.org/article/f4566cef942b4a59826c25a6c4414683
Autor:
Giuseppe Rubens Pascucci, Elena Morrocchi, Chiara Pighi, Arianna Rotili, Alessia Neri, Chiara Medri, Giulio Olivieri, Marco Sanna, Gianmarco Rasi, Deborah Persaud, Ann Chahroudi, Mathias Lichterfeld, Eleni Nastouli, Caterina Cancrini, Donato Amodio, Paolo Rossi, Nicola Cotugno, Paolo Palma
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 888 (2023)
Most of the current assays directed at the investigation of HIV reactivation are based on cultures of infected cells such as Peripheral Blood Mononuclear Cells (PBMCs) or isolated CD4+ T cells, stimulated in vitro with different activator molecules.
Externí odkaz:
https://doaj.org/article/dc66d2f161da44098e319b2590102f35
Autor:
Donato Amodio, Alessandra Ruggiero, Mayla Sgrulletti, Chiara Pighi, Nicola Cotugno, Chiara Medri, Elena Morrocchi, Luna Colagrossi, Cristina Russo, Salvatore Zaffina, Gigliola Di Matteo, Cristina Cifaldi, Silvia Di Cesare, Beatrice Rivalta, Lucia Pacillo, Veronica Santilli, Carmela Giancotta, Emma Concetta Manno, Marta Ciofi Degli Atti, Massimiliano Raponi, Paolo Rossi, Andrea Finocchi, Caterina Cancrini, Carlo Federico Perno, Viviana Moschese, Paolo Palma
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mass SARS-Cov-2 vaccination campaign represents the only strategy to defeat the global pandemic we are facing. Immunocompromised patients represent a vulnerable population at high risk of developing severe COVID-19 and thus should be prioritized in t
Externí odkaz:
https://doaj.org/article/9229bbff551247e3b32221fa6dc23567
Autor:
Nicola Cotugno, Enrica Franzese, Giulia Angelino, Donato Amodio, Erminia Francesca Romeo, Francesca Rea, Simona Faraci, Renato Tambucci, Elisa Profeti, Emma Concetta Manno, Veronica Santilli, Gioacchino Andrea Rotulo, Chiara Pighi, Chiara Medri, Elena Morrocchi, Luna Colagrossi, Giuseppe Rubens Pascucci, Diletta Valentini, Alberto Villani, Paolo Rossi, Paola De Angelis, Paolo Palma
Publikováno v:
Vaccines, Vol 10, Iss 7, p 1109 (2022)
Patients affected by Inflammatory Bowel Disease (IBD) present higher risk for infection and suboptimal response upon vaccination. The immunogenicity of SARS-CoV2 vaccination is still largely unknown in adolescents or young adults affected by IBD (pIB
Externí odkaz:
https://doaj.org/article/8c5aa35103be4aef9c3d465c73961ee0
Autor:
Cristina Capuano, Chiara Pighi, Simone Battella, Fabio Pulcinelli, Cristina Santoro, Antonietta Ferretti, Ombretta Turriziani, Davide De Federicis, Cinzia Fionda, Giuseppe Sciumè, Ricciarda Galandrini, Gabriella Palmieri
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 625 (2022)
In vivo establishment and long-term persistence of a heterogeneous memory or an adaptive NK cell pool represents a functional adaptation to human cytomegalovirus (HCMV) infection in humans. Memory NK cells are commonly identified by lack of the FcεR
Externí odkaz:
https://doaj.org/article/c07965110d39436fa2caf3d71cf43203
Autor:
Chang Jiang, Stephen J. Trudeau, Taek-Chin Cheong, Rui Guo, Mingxiang Teng, Liang Wei Wang, Zhonghao Wang, Chiara Pighi, Carole Gautier-Courteille, Yijie Ma, Sizun Jiang, Chong Wang, Bo Zhao, Luc Paillard, John G. Doench, Roberto Chiarle, Benjamin E. Gewurz
Publikováno v:
Cell Reports, Vol 28, Iss 5, Pp 1307-1322.e8 (2019)
Summary: CD40 has major roles in B cell development, activation, and germinal center responses. CD40 hypoactivity causes immunodeficiency whereas its overexpression causes autoimmunity and lymphomagenesis. To systematically identify B cell autonomous
Externí odkaz:
https://doaj.org/article/b74d5505048f47989a48f9086351ba64
Autor:
Cristina Capuano, Chiara Pighi, Simone Battella, Angela Santoni, Gabriella Palmieri, Ricciarda Galandrini
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Besides their innate ability to rapidly produce effector cytokines and kill virus-infected or transformed cells, natural killer (NK) cells display a strong capability to adapt to environmental modifications and to differentiate into long-lived, hyper
Externí odkaz:
https://doaj.org/article/e7b8e8ff4e8b469bb8af6a61078ecbaa