Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chiara Pasquino"'
Autor:
Giulia Chiabotto, Elena Ceccotti, Chiara Pasquino, Maria Beatriz Herrera Sanchez, Massimo Cedrino, Giovanni Camussi, Stefania Bruno
Publikováno v:
Exploration of Digestive Diseases, Vol 2, Iss 4, Pp 172-187 (2023)
Aim: Modifications in long non-coding RNA (lncRNA) expression are associated with inflammation and fibrosis in chronic liver diseases. It has been recently demonstrated that human liver stem cells (HLSCs) and their extracellular vesicles (EVs) can ef
Externí odkaz:
https://doaj.org/article/fc4a7c245b0f4b2396f894e3a30dca36
Autor:
Marta Tapparo, Gabriele Saccu, Chiara Pasquino, Valentina Fonsato, Claudio Medana, Valentina Schiavo, Enrica Mecarelli, Monica Maccagno, Lorenzo Silengo, Stefania Bruno, Giovanni Camussi, Maria Beatriz Herrera Sanchez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Introduction: The lack of functional hepatocytes poses a significant challenge for drug safety testing and therapeutic applications due to the inability of mature hepatocytes to expand and their tendency to lose functionality in vitro. Previous studi
Externí odkaz:
https://doaj.org/article/2297f9d0135249cba1b41372e9ebb979
Autor:
Stefania Bruno, Maria Beatriz Herrera Sanchez, Giulia Chiabotto, Valentina Fonsato, Victor Navarro-Tableros, Chiara Pasquino, Marta Tapparo, Giovanni Camussi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Human liver stem cells (HLSCs) were described for the first time in 2006 as a new stem cell population derived from healthy human livers. Like mesenchymal stromal cells, HLSCs exhibit multipotent and immunomodulatory properties. HLSCs can differentia
Externí odkaz:
https://doaj.org/article/70e67d23b858458fa484d685c6175a4d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
End-stage liver fibrosis is common to all chronic liver diseases. Since liver transplantation has several limitations, including lack of donors, immunological rejection, and high medical costs, therapeutic alternatives are needed. The administration
Externí odkaz:
https://doaj.org/article/2a91454d779546629b0e1a920ac66a88
Autor:
María José Ramírez-Bajo, Javier Martín-Ramírez, Stefania Bruno, Chiara Pasquino, Elisenda Banon-Maneus, Jordi Rovira, Daniel Moya-Rull, Marta Lazo-Rodriguez, Josep M. Campistol, Giovanni Camussi, Fritz Diekmann
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
BackgroundCell therapies and derived products have a high potential in aiding tissue and organ repairing and have therefore been considered as potential therapies for treating renal diseases. However, few studies have evaluated the impact of these th
Externí odkaz:
https://doaj.org/article/3eb20f3167e44bc9a582eab1586587c6
Autor:
Stefania Bruno, Maria Beatriz Herrera Sanchez, Chiara Pasquino, Marta Tapparo, Massimo Cedrino, Ciro Tetta, Giovanni Camussi
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Cell therapy may be regarded as a feasible alternative to whole organ transplantation to treat end-stage liver diseases. Human liver stem cells (HLSCs) are a population of cells easily obtainable and expandable from a human adult liver biopsy. HLSCs
Externí odkaz:
https://doaj.org/article/5207ac19e859425cb43dd2904b07334b
Autor:
Stefania Bruno, Cristina Grange, Marta Tapparo, Chiara Pasquino, Renato Romagnoli, Ennia Dametto, Antonio Amoroso, Ciro Tetta, Giovanni Camussi
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Human liver stem cells (HLSCs) are a mesenchymal stromal cell-like population resident in the adult liver. Preclinical studies indicate that HLSCs could be a good candidate for cell therapy. The aim of the present study was to evaluate the immunogeni
Externí odkaz:
https://doaj.org/article/219adffd3c274f5baaa38e4085876a59
Autor:
Stefania Bruno, Giulia Chiabotto, Massimo Cedrino, Elena Ceccotti, Chiara Pasquino, Samuela De Rosa, Cristina Grange, Stefania Tritta, Giovanni Camussi
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1485
International Journal of Molecular Sciences, Vol 23, Iss 1485, p 1485 (2022)
International Journal of Molecular Sciences, Vol 23, Iss 1485, p 1485 (2022)
The potential therapeutic effect of extracellular vesicles (EVs) that are derived from human liver stem cells (HLSCs) has been tested in an in vivo model of renal ischemia and reperfusion injury (IRI), that induce the development of chronic kidney di
Autor:
Stefania Bruno, Maria Beatriz Herrera Sanchez, Giulia Chiabotto, Valentina Fonsato, Victor Navarro-Tableros, Chiara Pasquino, Marta Tapparo, Giovanni Camussi
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Human liver stem cells (HLSCs) were described for the first time in 2006 as a new stem cell population derived from healthy human livers. Like mesenchymal stromal cells, HLSCs exhibit multipotent and immunomodulatory properties. HLSCs can differentia
Autor:
Giovanni Camussi, Victor Navarro-Tableros, Maria Chiara Deregibus, Sara Giunti, Marta Tapparo, Adriana Pitino, Yonathan Gomez, Ciro Tetta, Maria Felice Brizzi, Chiara Pasquino, Camillo Ricordi, Chiara Gai
Publikováno v:
Stem Cell Reviews
A potential therapeutic strategy for diabetes is the transplantation of induced-insulin secreting cells. Based on the common embryonic origin of liver and pancreas, we studied the potential of adult human liver stem-like cells (HLSC) to generate in v