Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chiara Orciani"'
Autor:
Morgan K. Foret, Chiara Orciani, Lindsay A. Welikovitch, Chunwei Huang, A. Claudio Cuello, Sonia Do Carmo
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Oxidative stress is a key contributor to AD pathology. However, the earliest role of pre-plaque neuronal oxidative stress, remains elusive. Using laser microdissected hippocampal neurons extracted from McGill-R-Thy1-APP transgenic rats we fo
Externí odkaz:
https://doaj.org/article/4578b327191040caa8b5143d7df20364
Autor:
Lisi Flores-Aguilar, M. Florencia Iulita, Chiara Orciani, Neil Tanna, Jingyun Yang, David A. Bennett, A. Claudio Cuello
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Background Brain inflammation has been increasingly associated with early amyloid accumulation in Alzheimer’s disease models; however, evidence of its occurrence in humans remains scarce. To elucidate whether amyloid deposition is associat
Externí odkaz:
https://doaj.org/article/724c4a65abb74d2bb8ccd76e0739fc4b
Autor:
Chiara Orciani, Sonia Do Carmo, Morgan K Foret, Hélène Hall, Quentin Bonomo, Agustina Lavagna, Chunwei Huang, Claudio A Cuello
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Chiara Orciani, Hélène Hall, Rowan Pentz, Morgan K. Foret, Sonia Do Carmo, Augusto Claudio Cuello
Publikováno v:
Journal of neurochemistryREFERENCES. 163(2)
Basal forebrain cholinergic neurons (BFCNs) represent the main source of cholinergic innervation to the cortex and hippocampus and degenerate early in Alzheimer's disease (AD) progression. Phenotypic maintenance of BFCNs depends on levels of mature n
Autor:
Lisi Flores‐Aguilar, Hélène Hall, Chiara Orciani, Morgan K. Foret, Olivia Kovecses, Adriana Ducatenzeiler, A. Claudio Cuello
Publikováno v:
Neuropathology and applied neurobiologyREFERENCES. 48(6)
The locus coeruleus (LC) is the main source of noradrenaline (NA) in the mammalian brain and has been found to degenerate during the initial stages of Alzheimer's disease (AD). Recent studies indicate that at late stages of the amyloid pathology, LC-
Publikováno v:
Alzheimer's & Dementia. 16
Publikováno v:
Free Radical Biology and Medicine. 159:S116
Autor:
Filippo Caraci, Chiara Orciani, Corrado Romano, Filippo Drago, Concetta Barone, M. Florencia Iulita, Rowan Pentz, Lisi Flores Aguilar, A. Claudio Cuello
Publikováno v:
European journal of pharmacology. 817
Individuals with Down syndrome are at increased risk of developing Alzheimer's disease due to increase gene dosage resulting from chromosome 21 triplication. Although virtually all adults with Down syndrome will exhibit the major neuropathological ha