Editorial: Unravelling Copper-Regulatory Systems and Copper-Affected Pathways in Cancer Cells to Improve Current Therapies

Autor: Xin Chen, Chiara Nardon, Q. Ping Dou

Publikováno v: Frontiers in Molecular Biosciences, Vol 9 (2022)

Externí odkaz: https://doaj.org/article/c663d43c63c44826a8511d963f02a782

Ln(III) Complexes Embedded in Biocompatible PLGA Nanoparticles as Potential Vis-to-NIR Optical Probes

Autor: Fabio Piccinelli, Silvia Mizzoni, Giorgia Zanella, Salvatore Calogero Gaglio, Massimiliano Perduca, Alessandro Romeo, Silvia Ruggieri, Chiara Nardon, Enrico Cavalli

Publikováno v: Molecules, Vol 28, Iss 5, p 2251 (2023)

In this contribution, we present the spectroscopic study of two NIR emitting hydrophobic heteroleptic (R,R)-YbL1(tta) and (R,R)-NdL1(tta) complexes (with tta = 2-thenoyltrifluoroacetonate and L1 = N,N′-bis(2-(8-hydroxyquinolinate)methylidene)-1,2-(

Externí odkaz: https://doaj.org/article/17405b5d429443e394cda1bd315c8915

Gold(III)-dithiocarbamato peptidomimetics in the forefront of the targeted anticancer therapy: preclinical studies against human breast neoplasia.

Autor: Chiara Nardon, Sara M Schmitt, Huanjie Yang, Jian Zuo, Dolores Fregona, Q Ping Dou

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e84248 (2014)

Since the serendipitous discovery of cisplatin, platinum-based drugs have become well-established antitumor agents, despite the fact that their clinical use is limited by many severe side-effects. In order to both improve the chemotherapeutic index a

Externí odkaz: https://doaj.org/article/ffc680e37eae45faa2fd6170d21def94

Near Infared Circularly Polarized Luminescence From Water Stable Organic Nanoparticles Containing a Chiral Yb(III) Complex

Autor: Enrico Cavalli, Chiara Nardon, Oliver G. Willis, Francesco Zinna, Lorenzo Di Bari, Silvia Mizzoni, Silvia Ruggieri, Salvatore C. Gaglio, Massimiliano Perduca, Claudio Zaccone, Alessandro Romeo, Fabio Piccinelli

Publikováno v: Chemistry – A European Journal. 28

We report the first example of very efficient NIR Circularly Polarized Luminescence (CPL) (around 970 nm) in water, obtained thanks to the combined use of a chiral Yb complex and of poly lactic-co-glycolic acid (PLGA) nanoparticles. [YbL(tta)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6d941c1704d4db6d3542a29a9c6fda
https://doi.org/10.1002/chem.202200574

CuIIand AuIIIComplexes with Glycoconjugated Dithiocarbamato Ligands for Potential Applications in Targeted Chemotherapy

Autor: Alberto Gambalunga, Federica Chiara, Barbara Biondi, Dolores Fregona, Chiara Nardon, Leonardo Brustolin, Andrea Trevisan, Nicolò Pettenuzzo, Elisa Coltri

Publikováno v: ChemMedChem
14 (2019): 1162–1172. doi:10.1002/cmdc.201900226
info:cnr-pdr/source/autori:Pettenuzzo, Nicolo; Brustolin, Leonardo; Coltri, Elisa; Gambalunga, Alberto; Chiara, Federica; Trevisan, Andrea; Biondi, Barbara; Nardon, Chiara; Fregona, Dolores/titolo:Cu-II and Au-III Complexes with Glycoconjugated Dithiocarbamato Ligands for Potential Applications in Targeted Chemotherapy/doi:10.1002%2Fcmdc.201900226/rivista:ChemMedChem (Print)/anno:2019/pagina_da:1162/pagina_a:1172/intervallo_pagine:1162–1172/volume:14

This work is focused on the synthesis, characterization, and preliminary biological evaluation of bio-conjugated Au-III and Cu-II complexes with the aim of overcoming the well-known side effects of chemotherapy by improving the selective accumulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578f3bccb791ec0d0cf39e8b20c9a839
https://doi.org/10.1002/cmdc.201900226