Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Chiara Mioni"'
Autor:
Davide Zaffe, Daniela Giuliani, Francesco Squadrito, Chiara Mioni, Alessandra Ottani, Annibale R. Botticelli, Alessandra Bitto, Salvatore Guarini, Letteria Minutoli, Maria Galantucci, Carla Bazzani
Publikováno v:
European Journal of Pharmacology. 570:57-65
In gerbils subjected to transient global cerebral ischemia, melanocortin peptides produce long-lasting protection with a broad time window, and through the activation of central nervous system melanocortin MC(4) receptors. Here we aimed to investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb8fb64dbb1da62dce5228651ceee10
https://doi.org/10.1016/j.ejphar.2007.05.025
https://doi.org/10.1016/j.ejphar.2007.05.025
Autor:
Aldo Tomasi, Anna Catania, S. Capolongo, A. R. Botticelli, Ettore Novellino, Anna Iannone, Carla Bazzani, Maria Galantucci, Gualtiero I. Colombo, Chiara Mioni, Davide Zaffe, Daniela Giuliani, Salvatore Guarini, Paolo Grieco, A. Sabba
Publikováno v:
British Journal of Pharmacology. 150:595-603
Background and purpose: In circulatory shock, melanocortins have life-saving effects likely to be mediated by MC4 receptors. To gain direct insight into the role of melanocortin MC4 receptors in haemorrhagic shock, we investigated the effects of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::240b31e777d05e3deb31c784306ca175
https://doi.org/10.1038/sj.bjp.0707115
https://doi.org/10.1038/sj.bjp.0707115
Autor:
Chiara Mioni, Margherita Calò, Mariarosaria Galeano, Alessandra Bitto, Francesca Polito, Venuti Fs, Daniela Giuliani, Patrizia Lo Cascio, Francesco Squadrito, Domenica Altavilla, Giovanni Giugliano, Letteria Minutoli, Giovanni Squadrito
Publikováno v:
Critical Care Medicine. 34:1139-1146
Erythropoietin interacts with vascular endothelial growth factor (VEGF) and stimulates endothelial cell mitosis and motility; thus it may be of importance in the complex phenomenon of wound healing. The purpose of this study was to investigate the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d4babee2cbbf770aac3a052ac5ee8c
https://doi.org/10.1097/01.ccm.0000206468.18653.ec
https://doi.org/10.1097/01.ccm.0000206468.18653.ec
Autor:
Francesco Arrigo, Francesco Saporito, Chiara Mioni, Domenica Altavilla, Antonio Micari, Francesco Squadrito, Alessandra Crisafulli, Gaspare D'Anneo, S. Raffa, Fabiana Lucà, Aurora Sardella, Maria Passaniti
Publikováno v:
Clinical Science. 109:389-395
OPG (osteoprotegerin) has been suggested to have an important role in atherogenesis and vascular calcification. In the present study, we have investigated serum OPG and RANKL (receptor activator of nuclear factor κB ligand) concentrations in patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4e516c1ea04461d1f06366d027a7c0
https://doi.org/10.1042/cs20050058
https://doi.org/10.1042/cs20050058
Autor:
Maria Michela Cainazzo, Helgi B. Schiöth, Alfio Bertolini, Carla Bazzani, Salvatore Guarini, Chiara Mioni, Giuseppe Ferrazza, Daniela Giuliani, Jarl E. S. Wikberg
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 366:177-182
Myocardial ischemia/reperfusion induces ventricular tachycardia (VT), ventricular fibrillation (VF) and a high degree of lethality. Since ACTH-(1-24) (adrenocorticotropin) protects against such injuries in rats, we investigated which melanocortin MC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73aa9eceafff35be595fc95c3b1fe5a9
https://doi.org/10.1007/s00210-002-0572-8
https://doi.org/10.1007/s00210-002-0572-8
Autor:
Domenica Altavilla, Chiara Mioni, Alfio Bertolini, Francesco Squadrito, Cristina Quartarone, Giovanni Squadrito, Domenico Cucinotta, Maria Michela Cainazzo, Carla Bazzani, Achille P. Caputi, Salvatore Guarini, Mariarita Arlotta, Antonino Saitta, Giuseppe M. Campo
Publikováno v:
British Journal of Pharmacology. 128:816-822
Tumour necrosis factor (TNF-α) is involved in the pathogenesis of splanchnic artery occlusion (SAO) shock. On the other hand, inhibition of TNF-α is an important component of the mechanism of action of melanocortins in reversing haemorrhagic shock.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58f57c5d19994515cea02c4788030458
https://doi.org/10.1038/sj.bjp.0702848
https://doi.org/10.1038/sj.bjp.0702848
Autor:
Davide Zaffe, Alessandra Ottani, Domenica Altavilla, Daniela Giuliani, Alessandra Bitto, Chiara Mioni, Maria Galantucci, Annibale R. Botticelli, Letteria Minutoli, Francesco Squadrito, Salvatore Guarini
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 29(3)
A vagus nerve-mediated, efferent cholinergic protective pathway activated by melanocortins is operative in circulatory shock and myocardial ischemia. Moreover, melanocortins have neuroprotective effects against brain damage after ischemic stroke. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675402023f5fda5c6f774483a5adf09e
https://pubmed.ncbi.nlm.nih.gov/19018269
https://pubmed.ncbi.nlm.nih.gov/19018269
Autor:
Francesco Messineo, Vincenzo De Meo, Albertino Bigiani, Domenica Altavilla, Venuti Fs, Daniela Giuliani, Francesco Squadrito, Chiara Mioni, Giovanni Squadrito, Salvatore Guarini, Carla Bazzani, Letteria Minutoli, Alessandra Bitto
The cholinergic anti-inflammatory pathway has not yet been studied in splanchnic artery occlusion (SAO) shock. We investigated whether electrical stimulation (STIM) of efferent vagus nerves suppresses the inflammatory cascade in SAO shock. Animals we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd9b129f86ef77ecd76c5814db8d570
http://hdl.handle.net/11570/1839100
http://hdl.handle.net/11570/1839100
Autor:
Letteria Minutoli, Alessandra Bitto, Maria Galantucci, Salvatore Guarini, Daniela Giuliani, Carla Bazzani, Francesco Squadrito, Chiara Mioni, Sheila Leone, Davide Zaffe, Domenica Altavilla, Annibale R. Botticelli
Melanocortin peptides have been shown to produce neuroprotection in experimental ischemic stroke. The aim of the present investigation was to identify the therapeutic treatment window of melanocortins, and to determine whether these neuropeptides chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b292a50b8ab86794e9a586650b9171a2
http://hdl.handle.net/11570/1891838
http://hdl.handle.net/11570/1891838
Autor:
Sheila Leone, Davide Zaffe, Daniela Necchi, Alfio Bertolini, Chiara Mioni, Letteria Minutoli, Helgi B. Schiöth, Francesco Squadrito, Daniela Giuliani, Alessandra Bitto, Domenica Altavilla, Salvatore Guarini, Annibale R. Botticelli, Carla Bazzani, Roberto Pizzala, Herbert Marini, Maria Michela Cainazzo, Monica Savio
Ischemic stroke is one of the main causes of death and disability. We investigated whether melanocortin peptides, which have protective effects in severe hypoxic conditions, also produce neuroprotection in a gerbil model of ischemic stroke. A 10-min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee60245c6bedbeb4fdbb09e51afec85
http://hdl.handle.net/11570/1669342
http://hdl.handle.net/11570/1669342