Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Chiara Maria Mazzanti"'
Autor:
Roberto Silvestri, Filomena Rea, Marianna Vitiello, Gabriele Moretti, Vittorio Aprile, Marco Lucchi, Paolo Aretini, Chiara Maria Mazzanti, Stefano Landi, Federica Gemignani
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32152- (2024)
Objectives: This study aims to determine whether the sequencing of DNA extracted from pleural fluids (PFs) of Pleural Mesothelioma (PM) patients accurately represents the genetic information obtained from the solid tissue counterpart biopsies with pa
Externí odkaz:
https://doaj.org/article/4e2a57cd4d2047b8b378ebb94f5af9b0
Autor:
Mariangela Morelli, Francesca Lessi, Sara Franceschi, Gianmarco Ferri, Manuel Giacomarra, Michele Menicagli, Carlo Gambacciani, Francesco Pieri, Francesco Pasqualetti, Nicola Montemurro, Paolo Aretini, Orazio Santo Santonocito, Anna Luisa Di Stefano, Chiara Maria Mazzanti
Publikováno v:
Cells, Vol 13, Iss 6, p 487 (2024)
Glioblastoma, a deadly brain tumor, shows limited response to standard therapies like temozolomide (TMZ). Recent findings from the REGOMA trial underscore a significant survival improvement offered by Regorafenib (REGO) in recurrent glioblastoma. Our
Externí odkaz:
https://doaj.org/article/cb05bb8548ac4d87af3236dc9cdad224
Autor:
Alberto Picca, Giulio Sansone, Orazio Santo Santonocito, Chiara Maria Mazzanti, Marc Sanson, Anna Luisa Di Stefano
Publikováno v:
Cancers, Vol 15, Iss 23, p 5555 (2023)
In 2012, whole-transcriptome sequencing analysis led to the discovery of recurrent fusions involving the FGFR3 and TACC3 genes as the main oncological driver in a subset of human glioblastomas. Since then, FGFR3-TACC3 fusions have been identified in
Externí odkaz:
https://doaj.org/article/8da6b497700c42f9958c90715005a43a
Autor:
Francesca Parisi, Francesca Lessi, Michele Menicagli, Prospero Civita, Romano Liotti, Francesca Millanta, Giulia Freer, Mauro Pistello, Chiara Maria Mazzanti, Alessandro Poli
Publikováno v:
Infectious Agents and Cancer, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract The mouse mammary tumour virus (MMTV) is implicated in the aetiology of murine mammary carcinomas and a variant of it, the type B leukemogenic virus, can cause murine thymic lymphomas. Interestingly, a MMTV-like virus is suspected to be invo
Externí odkaz:
https://doaj.org/article/f48027f7d2c943a5b0c27758c98d4ed8
Autor:
Mariangela Morelli, Francesca Lessi, Serena Barachini, Romano Liotti, Nicola Montemurro, Paolo Perrini, Orazio Santo Santonocito, Carlo Gambacciani, Matija Snuderl, Francesco Pieri, Filippo Aquila, Azzurra Farnesi, Antonio Giuseppe Naccarato, Paolo Viacava, Francesco Cardarelli, Gianmarco Ferri, Paul Mulholland, Diego Ottaviani, Fabiola Paiar, Gaetano Liberti, Francesco Pasqualetti, Michele Menicagli, Paolo Aretini, Giovanni Signore, Sara Franceschi, Chiara Maria Mazzanti
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundGlioblastoma (GB) is the most severe form of brain cancer, with a 12-15 month median survival. Surgical resection, temozolomide (TMZ) treatment, and radiotherapy remain the primary therapeutic options for GB, and no new therapies have been
Externí odkaz:
https://doaj.org/article/a0c643cddb5e4ccf92ca9ca6b88b0ff3
Autor:
Raffaele Gaeta, Mariangela Morelli, Francesca Lessi, Chiara Maria Mazzanti, Michele Menicagli, Rodolfo Capanna, Lorenzo Andreani, Luca Coccoli, Paolo Aretini, Alessandro Franchi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10086 (2023)
Conventional high-grade osteosarcoma (OS) is the most common primary cancer of bone and it typically affects the extremities of adolescents. OS has a complex karyotype, and molecular mechanisms related to carcinogenesis, progression and resistance to
Externí odkaz:
https://doaj.org/article/0d42a700d22f4ad894da67ecb44877c5
Autor:
Francesca Lessi, Mariangela Morelli, Sara Franceschi, Paolo Aretini, Michele Menicagli, Andrea Marranci, Francesco Pasqualetti, Carlo Gambacciani, Francesco Pieri, Gianluca Grimod, Vanna Zucchi, Samanta Cupini, Anna Luisa Di Stefano, Orazio Santo Santonocito, Chiara Maria Mazzanti
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10147 (2023)
Circulating tumor cells (CTCs) are one of the most important causes of tumor recurrence and distant metastases. Glioblastoma (GBM) has been considered restricted to the brain for many years. Nevertheless, in the past years, several pieces of evidence
Externí odkaz:
https://doaj.org/article/d16d19be41cd4c579ac828fde9d0c6de
Autor:
Francesca Lessi, Paolo Aretini, Milena Rizzo, Mariangela Morelli, Michele Menicagli, Sara Franceschi, Chiara Maria Mazzanti
Publikováno v:
Cell Adhesion & Migration, Vol 15, Iss 1, Pp 180-201 (2021)
MiRNAs represent a mechanism that regulates gene expression in many pathological conditions. Exosomes are known to be secreted from all types of cells, and the exosomes-released molecules are crucial messengers that can regulate cellular processes. W
Externí odkaz:
https://doaj.org/article/209d36481a1b4066acb80f61c70be561
Autor:
Elisa Degl’Innocenti, Tino Emanuele Poloni, Valentina Medici, Luca Recupero, Claudia Dell’Amico, Eleonora Vannini, Ugo Borello, Chiara Maria Mazzanti, Marco Onorati, Maria Teresa Dell’Anno
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
As microtubule-organizing centers (MTOCs), centrosomes play a pivotal role in cell division, neurodevelopment and neuronal maturation. Among centrosomal proteins, centrin-2 (CETN2) also contributes to DNA repair mechanisms which are fundamental to pr
Externí odkaz:
https://doaj.org/article/33c473c9c69e4034bf3c60d603a5eff7
Autor:
Cristian Scatena, Sara Franceschi, Maria Franzini, Chiara Sanguinetti, Nadia Romiti, Laura Caponi, Mario Mandalà, Chiara Maria Mazzanti, Antonio Giuseppe Naccarato
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Neoplastic cells promote a hypercoagulable state by the expression of cell surface proteins, such as tissue factor. In BRAFv600 mutated melanoma patients upon BRAF inhibitors, a hypercoagulable state correlates with prognosis, whi
Externí odkaz:
https://doaj.org/article/cb3e35aeda904db5b9f43d41ed771174