Molecular Imaging of Pulmonary Tuberculosis in an Ex-Vivo Mouse Model Using Spectral Photon-Counting Computed Tomography and Micro-CT

Autor: Chiara Lowe, Ana Ortega-Gil, Mahdieh Moghiseh, Nigel G. Anderson, Arrate Munoz-Barrutia, Juan Jose Vaquero, Aamir Y. Raja, Aysouda Matanaghi, Alexander I. Chernoglazov, Theodorus Dapamede, Sikiru A Adebileje, Steven Alexander, Maya R. Amma, Marzieh Anjomrouz, Fatemeh Asghariomabad, Ali Atharifard, James Atlas, Kenzie Baer, Stephen T. Bell, Srinidhi Bheesette, Philip H. Butler, Pierre Carbonez, Claire Chambers, Krishna M. Chapagain, Jennifer A. Clark, Frances Colgan, Jonathan S. Crighton, Shishir Dahal, Jerome Damet, Niels J. A. De Ruiter, Robert M. N. Doesburg, Neryda Duncan, Nooshin Ghodsian, Steven P. Gieseg, Brian P. Goulter, Sam Gurney, Joseph L. Healy, Praveen Kumar Kanithi, Tracy Kirkbride, Stuart P. Lansley, V. B. H. Mandalika, Emmanuel Marfo, David Palmer, Raj K. Panta, Hannah M. Prebble, Peter Renaud, Yann Sayous, Nanette Schleich, Emily Searle, Jereena S. Sheeja, Lieza Vanden Broeke, Vivek V. S., E. Peter Walker, Michael F. Walsh, Manoj Wijesooriya, W Ross Younger, Anthony P. H. Butler

Publikováno v: IEEE Access, Vol 9, Pp 67201-67208 (2021)

Assessment of disease burden and drug efficacy is achieved preclinically using high resolution micro computed tomography (CT). However, micro-CT is not applicable to clinical human imaging due to operating at high dose. In addition, the technology di

Externí odkaz: https://doaj.org/article/7b404ed8b5674a7093261f5b00a5ed03

Hitchhiking probiotic vectors to deliver ultra-small hafnia nanoparticles for ‘Color’ gastrointestinal tract photon counting X-ray imaging

Autor: Fatemeh Ostadhossein, Parikshit Moitra, Nivetha Gunaseelan, Michael Nelappana, Chiara Lowe, Mahdieh Moghiseh, Anthony Butler, Niels de Ruiter, Harish Mandalika, Indu Tripathi, Santosh K. Misra, Dipanjan Pan

Publikováno v: Nanoscale Horizons. 7:533-542

Gastrointestinal (GI) tract is one of the hard-to-reach target tissues for the delivery of contrast agents and drugs mediated by nanoparticles due to its harsh environment. Herein, we overcame this barrier by designing orally ingestible probiotic vec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654f5610855c50394236ca342069dd03
https://doi.org/10.1039/d1nh00626f

Assessment of Material Identification Errors, Image Quality, and Radiation Doses Using Small Animal Spectral Photon-Counting CT

Autor: Anthony Butler, Jerome Damet, Joe Healy, Chiara Lowe, Nanette Schleich, Emmanuel Marfo, Aamir Y. Raja, Alexander I. Chernoglazov, Mahdieh Moghiseh, Pierre Carbonez, Nigel G. Anderson

Publikováno v: IEEE Transactions on Radiation and Plasma Medical Sciences. 5:578-587

Photon-counting CT offers the potential to provide new diagnostic information. In this study, we sought to determine the interplay between material identification errors, image quality indicators, and radiation doses using photon-counting spectral CT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae5e53b94d2b8427d8a46af6ca6b9448
https://doi.org/10.1109/trpms.2020.3003260

Molecular imaging of pulmonary tuberculosis in an ex-vivo mouse model using spectral photon-counting computed tomography and micro-CT

Autor: Michael F. Walsh, V. S. Vivek, Emmanuel Marfo, Fatemeh Asghariomabad, Ali Atharifard, Nigel G. Anderson, David Palmer, Ana Ortega-Gil, Claire Chambers, Peter Renaud, Srinidhi Bheesette, Neryda Duncan, Yann Sayous, Arrate Muñoz-Barrutia, Stephen T. Bell, Jerome Damet, Theodorus Dapamede, Raj K. Panta, E. Peter Walker, Alexander I. Chernoglazov, Jereena S. Sheeja, Frances Colgan, Joseph L. Healy, Manoj Wijesooriya, Juan José Vaquero, Praveen Kumar Kanithi, James Atlas, R. Doesburg, Philip H Butler, Lieza Vanden Broeke, Hannah M. Prebble, Steven D Alexander, W. Ross Younger, Nanette Schleich, Aamir Y. Raja, Brian P. Goulter, V. B. H. Mandalika, Krishna M. Chapagain, Niels J A de Ruiter, Chiara Lowe, Maya R Amma, Kenzie Baer, Mahdieh Moghiseh, Aysouda Matanaghi, Shishir Dahal, Emily Searle, Nooshin Ghodsian, Steven P. Gieseg, Anthony Butler, Jonathan S. Crighton, Sikiru A Adebileje, Sam Gurney, Pierre Carbonez, Tracy Kirkbride, Stuart P. Lansley, Jennifer A. Clark, Marzieh Anjomrouz

Publikováno v: e-Archivo: Repositorio Institucional de la Universidad Carlos III de Madrid
Universidad Carlos III de Madrid (UC3M)
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
instname
IEEE Access, Vol 9, Pp 67201-67208 (2021)

Assessment of disease burden and drug efficacy is achieved preclinically using high resolution micro computed tomography (CT). However, micro-CT is not applicable to clinical human imaging due to operating at high dose. In addition, the technology di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc3143202b419e2aa50986d83d00552
http://hdl.handle.net/10016/32612

Spectral CT Imaging Using MARS Scanners

Autor: Ali Atharifard, E. Peter Walker, Philip H Butler, Lieza Vanden Broeke, Nanette Schleich, Hannah M. Prebble, Srinidhi Bheesette, Rayhan Uddin, Alexander I. Chernoglazov, Benjamin Bamford, Praveen Kumar Kanithi, Steven D Alexander, Raj K. Panta, Jerome Damet, Stephen T. Bell, Aamir Y. Raja, Jereena S. Sheeja, Brian P. Goulter, Manoj Wijesooriya, Joseph L. Healy, R. Doesburg, Sikiru A Adebileje, V. B. H. Mandalika, Michael F. Walsh, Niels J A de Ruiter, Emmanuel Marfo, Fatemeh Asghariomabad, Maya R Amma, Shishir Dahal, Emily Searle, Stuart P. Lansley, Mahdieh Moghiseh, Pierre Carbonez, Chiara Lowe, Aysouda Matanaghi, Steven P. Gieseg, Anthony Butler, V. S. Vivek

Publikováno v: Spectral, Photon Counting Computed Tomography ISBN: 9780429486111

Photon-counting spectral CT requires accurate and efficient detection of photons across the broad x-ray spectrum. MARS photon-counting spectral CT imaging is an emerging technology on the clinical horizon, providing a highly specific 3D material imag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d3488fe3486351ef494bcec312ab8e8
https://doi.org/10.1201/9780429486111-7