Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Chiara Grisanzio"'
Autor:
Jean-Christophe Pignon, Chiara Grisanzio, Ingrid Carvo, Lillian Werner, Meredith Regan, E Lynette Wilson, Sabina Signoretti
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128489 (2015)
There is evidence that stem cells and their progeny play a role in the development of the prostate. Although stem cells are also considered to give rise to differentiated progeny in the adult prostate epithelium ex vivo, the cohort of adult prostate
Externí odkaz:
https://doaj.org/article/c3a454f793b94968b7d9667c2b6c44fc
Autor:
Sabina Signoretti, Pedram Argani, Chiara Grisanzio, Yihong Wang, Yineng Fu, Musie Ghebremichael, Robert M. Najarian, Elizabeth M. Genega
Publikováno v:
American Journal of Clinical Pathology. 134:873-879
Carbonic anhydrase IX (CAIX), a hypoxia-induced protein, is expressed in some renal tumors. We evaluated its immunohistochemical expression in 317 primary and 42 metastatic renal neoplasms (186 clear cell, 52 papillary, 35 chromophobe, 47 unclassifie
Autor:
William G. Kaelin, Susanne Schlisio, Arthur P. Young, Chiara Grisanzio, Sabina Signoretti, Yoji Andrew Minamishima, Qing Zhang, Lianjie Li
Publikováno v:
Nature Cell Biology. 10:361-369
Germline von Hippel-Lindau tumour suppressor gene (VHL) mutations cause renal cell carcinomas, haemangioblastomas and phaeochromocytomas in humans. Mutations in VHL also occur in sporadic renal cell carcinomas. The protein encoded by VHL, VHL, is par
Autor:
Chiara Grisanzio, Ramesh A. Shivdasani, Jean-Christophe Pignon, Sabina Signoretti, Yan Geng, Jiaxi Song
The tumor protein p63 (p63), and more specifically the NH2-terminal truncated (ΔN) p63 isoform, is a marker of basal epithelial cells and is required for normal development of several epithelial tissues, including the bladder and prostate glands. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc6964f915a78e8dae78f78c6782db5
https://europepmc.org/articles/PMC3657776/
https://europepmc.org/articles/PMC3657776/
Autor:
Ashutosh Tewari, Ian G. Mills, Massimo Loda, Masahito Kido, Prasanna Sooriakumaran, David Y. Takeda, Helen Ross-Adams, Robert Leung, William C. Hahn, Anna C. Schinzel, Philip W. Kantoff, Gillian Petrozziello, Mark Pomerantz, David E. Neal, Bisola C. Awoyemi, Edward C. Stack, Lillian Werner, Rosina T. Lis, Matthew L. Freedman, Oliver Sartor, Toshihiro Yamamoto, Hiroki Yamada, Shin Egawa, Chiara Grisanzio, Brian D. Robinson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(28)
One of the central goals of human genetics is to discover the genes and pathways driving human traits. To date, most of the common risk alleles discovered through genome-wide association studies (GWAS) map to nonprotein-coding regions. Because of our
Autor:
Rameen Beroukhim, Chiara Grisanzio, Michelle Chang, Arianna Di Napoli, Andrew Percy, Michael Collins, Sabina Signoretti, Apryle Seeley, Su Chun Cheng
Renal cell carcinoma (RCC) is an aggressive malignancy with limited responsiveness to existing treatments. In vivo models of human cancer, including RCC, are critical for developing more effective therapies. Unfortunately, current RCC models do not a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a4fff339e126fe44323a3ef9c8047b
http://hdl.handle.net/11573/383816
http://hdl.handle.net/11573/383816
Autor:
Matthew L. Freedman, Chiara Grisanzio
Genome-wide association studies (GWAS) have successfully identified common polymorphisms that are strongly associated with many traits, including cancer. A gene desert located on chromosome 8q24 is associated with multiple cancer types. One of the cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096c505609077b979bf50b94bc197fb8
https://europepmc.org/articles/PMC3092220/
https://europepmc.org/articles/PMC3092220/
Autor:
Nasim Ahmadiyeh, Housheng Hansen He, Jennifer L. Caswell, Meredith M. Regan, Matthew L. Freedman, Matthew J. Davis, Myles Brown, Li Jia, Vanessa Almendro, Laura E. MacConaill, Chiara Grisanzio, X. Shirley Liu, Christine A. Beckwith, Mark Pomerantz, Paula Herman, Gerhard A. Coetzee, Adam Hills
The 8q24 gene desert contains risk loci for multiple epithelial cancers, including colon, breast, and prostate. Recent evidence suggests these risk loci contain enhancers. In this study, data are presented showing that each risk locus bears epigeneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d921edfa9781ba9dc8f439d45bf101
https://europepmc.org/articles/PMC2906844/
https://europepmc.org/articles/PMC2906844/
Autor:
Jing Ma, Lorelei A. Mucci, Stacey Ruiz, Chiara Grisanzio, Giorgia Zadra, Toshiro Migita, Stephen P. Finn, Eyoung Shin, Carmen Priolo, Michelangelo Fiorentino, Fumika Inazuka, Meir J. Stampfer, Andrew L. Kung, Sabina Signoretti, Phillip G. Febbo, Emanuele Palescandolo, Wanling Xie, Alessandro Fornari, William C. Hahn, Christopher Fiore, Massimo Loda, Aravind Subramanian
Publikováno v:
Journal of the National Cancer Institute. 101(7)
BACKGROUND: Overexpression of the fatty acid synthase (FASN) gene has been implicated in prostate carcinogenesis. We sought to directly assess the oncogenic potential of FASN. METHODS: We used immortalized human prostate epithelial cells (iPrECs), an
Autor:
Chiara Grisanzio, Sabina Signoretti
Publikováno v:
Stem Cells and Cancer ISBN: 9781603279321
Cancer is thought to develop from the neoplastic transformation of either stem cells that maintain the ability to self-renew or committed progenitor cells that undergo dedifferentiation and acquire stem cell characteristics. Thus, understanding prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c969ab1c05fcda442da8a57b541437aa
https://doi.org/10.1007/978-1-60327-933-8_18
https://doi.org/10.1007/978-1-60327-933-8_18