Zobrazeno 1 - 10 of 124 pro vyhledávání: '"Chiara Ghiron"'
1
Akademický článek
The Primo Vascular System as a Possible Exosomal Route Across the Body: Implications for Tumor Proliferation and Metastasis
Autor: Chiara Ghiron
Publikováno v: Journal of Acupuncture & Meridian Studies, Vol 12, Iss 1, Pp 25-28 (2019)
This literature study article will present the possibility of a correlation between the energy meridians of Traditional Chinese Medicine, which can be traced back to the recently described primo vessels (formerly known as Bong-Han ducts), their compo
Externí odkaz: https://doaj.org/article/fc00a3427cfb47ccbe8c158ecb826a3c
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2
Elektronická kniha
Exercises in Synthetic Organic Chemistry
Autor: Chiara Ghiron, Russell J. Thomas
The book is comprised of a series of exercises in synthetic organic chemistry based around recent published syntheses. The exercises are designed to provide challenges for people with varying levels of experience from final year students to academic
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3
The Primo Vascular System as a Possible Exosomal Route Across the Body: Implications for Tumor Proliferation and Metastasis
Autor: Chiara Ghiron
Publikováno v: Journal of Acupuncture & Meridian Studies, Vol 12, Iss 1, Pp 25-28 (2019)
This literature study article will present the possibility of a correlation between the energy meridians of Traditional Chinese Medicine, which can be traced back to the recently described primo vessels (formerly known as Bong-Han ducts), their compo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a04ea9d3cdcc084e312e5220d2d7775
https://pubmed.ncbi.nlm.nih.gov/29940372
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4
Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach
Autor: John Lunec, Iolanda Micco, Bernard T. Golding, Graeme Robertson, Matteo Magnani, Xiaohong Lu, Junfeng Liu, Ian R. Hardcastle, Alessandro Padova, Chiara Ghiron, Barry Dodd, Roger J. Griffin, Andrey V. Zaytsev, David R. Newell
Publikováno v: Chemical Biology & Drug Design. 86:180-189
Two libraries of substituted benzimidazoles were designed using a 'scaffold-hopping' approach based on reported MDM2-p53 inhibitors. Substituents were chosen following library enumeration and docking into an MDM2 X-ray structure. Benzimidazole librar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e935482988bc20883519506bb986367
https://doi.org/10.1111/cbdd.12474
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5
Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor
Autor: Simon N. Haydar, Jean Zhang, John Dunlop, Arianna Nencini, Laura Maccari, Elisa Turlizzi, Riccardo Zanaletti, Thomas A. Comery, Chiara Ghiron, Eva Genesio, Iolanda Micco, Cristiana Castaldo
Publikováno v: European Journal of Medicinal Chemistry. 78:401-418
α7 nicotinic acetylcholine receptor agonists are promising therapeutic candidates for the treatment of cognitive impairment. As a follow up of our internal medicinal chemistry program we investigated a novel series of α7 nAChR agonists. Starting fr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139ec03023d3491022a7083c4d811190
https://doi.org/10.1016/j.ejmech.2014.03.031
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9
Synthesis of Novel 4-Fluoro-2H-pyrazol-3-ylamines
Autor: Riccardo Zanaletti, Iolanda Micco, Chiara Ghiron, Giuseppe Cocconcelli, Simon Haydar
Publikováno v: Synthetic Communications. 40:2547-2555
A new and efficient synthesis for the preparation of novel 4-fluoro-2H-pyrazol-3-ylamines is described. It involves the reaction of an acyl chloride with fluoroacetonitrile and sequential ring closure of the α-fluoro-β-ketonitrile with hydrazine. U
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dafe76eaed2ed6f8917aa0eca73f34e7
https://doi.org/10.1080/00397910903277912
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10
Rapid Combinatorial Access to a Library of 1,5-Disubstituted-3-indole-N-alkylacetamides as CB2 Receptor Ligands
Autor: Federico Corelli, Serena Pasquini, Alessia Ligresti, Claudia Mugnaini, Vincenzo Di Marzo, Antonella Brizzi, Chiara Ghiron
Publikováno v: Journal of combinatorial chemistry 11 (2009): 795–798. doi:10.1021/cc9000955
info:cnr-pdr/source/autori:Pasquini S; Mugnaini C; Brizzi A; Ligresti A; Di Marzo V; Ghiron C; Corelli F/titolo:Rapid combinatorial access to a library of 1,5-disubstituted-3-indole-N-alkylacetamides as CB2 receptor ligands/doi:10.1021%2Fcc9000955/rivista:Journal of combinatorial chemistry/anno:2009/pagina_da:795/pagina_a:798/intervallo_pagine:795–798/volume:11
In our research program on new cannabinoid receptor modulators,9-11 we decided to investigate the possibility to identify novel CB2 ligands starting from commercially available 5-hydroxyindole-3-acetic acid (Figure 2). This scaffold offers three poin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48138b69c506875e1d3743fbd775d25
https://doi.org/10.1021/cc9000955
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