Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Chiara Galloni"'
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Akademický článek
Brain endothelial cells promote breast cancer cell extravasation to the brain via EGFR-DOCK4-RAC1 signalling
Autor: Chiara Galloni, Teklu Egnuni, Safoura Zahed Mohajerani, Jiaqi Ye, Sibylle Mittnacht, Valerie Speirs, Mihaela Lorger, Georgia Mavria
Publikováno v: Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract The role of endothelial cells in promoting cancer cell extravasation to the brain during the interaction of cancer cells with the vasculature is not well characterised. We show that brain endothelial cells activate EGFR signalling in triple-
Externí odkaz: https://doaj.org/article/cd26aee6a2a548fb9ca20940a8ec9c7a
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MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes
Autor: Christophe Guérin, Pavithra Singaravelu, Laurent Blanchoin, Naoko Kogata, Svend Kjaer, Davide Carra, Michael Way, Chiara Galloni, Jasmine V. Abella, David J. Barry
Publikováno v: The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology, 2021, 220 (8), pp.e202102043. ⟨10.1083/jcb.202102043⟩
Journal of Cell Biology, Rockefeller University Press, 2021, 220 (8), pp.e202102043. ⟨10.1083/jcb.202102043⟩
Galloni, Carra, et al. demonstrate that Arp3B isoform–specific Arp2/3 complexes generate branched actin networks with faster disassembly kinetics. This increased turnover is due to oxidation of Met293 of Arp3B by the methionine monooxygenase MICAL2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d9076f307f4a81eb04977bef68a426
http://europepmc.org/articles/PMC8193582
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MICAL2 acts through Arp3B isoform-specific Arp2/3 complexes to destabilize branched actin networks
Autor: Svend Kjaer, Laurent Blanchoin, Davide Carra, Michael Way, David J. Barry, Jasmine V. Abella, Pavithra Singaravelu, Chiara Galloni, Naoko Kogata, Christophe Guérin
The Arp2/3 complex (Arp2, Arp3 and ARPC1-5) is essential to generate branched actin filament networks for many cellular processes. Human Arp3, ARPC1 and ARPC5 exist as two isoforms but the functional properties of Arp2/3 iso-complexes is largely unex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a77a1713d8760418fd1c0cef81af3bc
https://doi.org/10.1101/2020.09.21.306522
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4
Efficacy of a film-forming medical device containing sunscreen (50+) and piroxicam 0.8% in actinic keratosis and field cancerization: a multicenter, assessor-blinded, 3 month trial
Autor: Elena Campione, Giovanna Tilotta, Virginia Garofalo, Silvia Lovati, Silvia Marchetti, Laura Diluvio, Massimo Milani, Giuseppe Scarcella, Luca Bianchi, Valentina Caputo, Giuseppe Pistone, Chiara Galloni, Paolo Sergio Pavone, Mario Puviani
Publikováno v: Current medical research and opinion. 33(7)
Sunscreen protection in subjects with actinic keratosis (AK) is highly recommended to prevent clinical evolution of this in situ skin cancer condition. Use of topical anti-cyclooxygenase drugs such as diclofenac and piroxicam reduces the number of le
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf377f67eac26ab66f5ed38e713234ee
https://pubmed.ncbi.nlm.nih.gov/28358282
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5
Isoform diversity in the Arp2/3 complex determines actin filament dynamics
Autor: Svend Kjaer, Michael Way, Marie-France Carlier, Chiara Galloni, Jasmine V. Abella, Julien Pernier, David J. Barry
Publikováno v: Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2016, pp.76-86. 〈10.1038/ncb3286〉
Nature Cell Biology, Nature Publishing Group, 2016, pp.76-86. ⟨10.1038/ncb3286⟩
Nature Cell Biology, 2016, pp.76-86. ⟨10.1038/ncb3286⟩
International audience; The Arp2/3 complex consists of seven evolutionarily conserved subunits (Arp2, Arp3 and ARPC1-5) and plays an essential role in generating branched actin filament networks during many different cellular processes. In mammals, h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd4b02510db5c64a3e5e283e2a36c724
https://pubmed.ncbi.nlm.nih.gov/26693915
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6
Cytoplasmatic compartmentalization by Bcr-Abl promotes TET2 loss-of-function in chronic myeloid leukemia
Autor: Chiara Galloni, Manuela Mancini, Elisa Leo, Enza Barbieri, Ilaria Iacobucci, Michela Aluigi, Enrica Borsi, Nevena Veljkovic, Maria Alessandra Santucci
Publikováno v: Journal of Cellular Biochemistry
The loss-of-function of teneleven-translocation (TET) 2, a Fe2+-oxoglutarate-dependent dioxygenase catalyzing 5 methyl cytosine (5mC) conversion into 5-hydroxymethylcytosine (5hmC), contributes to the hematopoietic transformation in vivo. The aim of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4d28b74563c43729709db7ebae27e7
https://pubmed.ncbi.nlm.nih.gov/22467095
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9
Precalcaneal congenital fibrolipomatous hamartoma
Autor: Chiara Galloni, R. Cavalli, Stefano Cambiaghi, Lucia Restano
Publikováno v: International Journal of Dermatology. 45:1202-1203
The patients are four unrelated children, one boy and three girls, aged between 3 and 7 months. All the patients were born at term, had normal postnatal development, and were in good general health. Each child presented from birth with a single plant
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fb7a5e9b2609c6f9abd932e69921ef
https://doi.org/10.1111/j.1365-4632.2006.02665.x
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