Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Chiara Falcicchia"'
Autor:
Nimra Aziz, Chiara Ruzza, Chiara Falcicchia, Annunziata Guarino, Marie Soukupova, Laila Asth, Valentina Aleotti, Barbara Bettegazzi, Michele Simonato, Silvia Zucchini
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4160 (2024)
Neuroinflammation is associated with several neurological disorders including temporal lobe epilepsy. Seizures themselves can induce neuroinflammation. In an in vivo model of epilepsy, the supplementation of brain-derived neurotropic factor (BDNF) an
Externí odkaz:
https://doaj.org/article/21c22698d45b442c88399574371a985b
Autor:
Francesca Tozzi, Grazia Rutigliano, Marco Borsò, Chiara Falcicchia, Riccardo Zucchi, Nicola Origlia
Publikováno v:
Neurobiology of Disease, Vol 151, Iss , Pp 105271- (2021)
Abnormalities in thyroid hormones (TH) availability and/or metabolism have been hypothesized to contribute to Alzheimer's disease (AD) and to be a risk factor for stroke. Recently, 3-iodothyronamine (T1AM), an endogenous amine putatively derived from
Externí odkaz:
https://doaj.org/article/db20c8dd7d2c440a93b68a224c837634
Autor:
Andrea Mazzatenta, Giampiero Neri, Damiano D'Ardes, Carlo De Luca, Stefano Marinari, Ettore Porreca, Francesco Cipollone, Jacopo Vecchiet, Chiara Falcicchia, Vincenzo Panichi, Nicola Origlia, Camillo Di Giulio
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
One of the most striking reported symptoms in CoViD-19 is loss of smell and taste. The frequency of these impairments and their specificity as a potential central nervous system function biomarker are of great interest as a diagnostic clue for CoViD-
Externí odkaz:
https://doaj.org/article/b238dec893f84029bd6195b3cf03ea49
Autor:
Chiara Falcicchia, Giovanna Paolone, Dwaine F. Emerich, Francesca Lovisari, William J. Bell, Tracie Fradet, Lars U. Wahlberg, Michele Simonato
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss , Pp 211-224 (2018)
Brain-derived neurotrophic factor (BDNF) may represent a therapeutic for chronic epilepsy, but evaluating its potential is complicated by difficulties in its delivery to the brain. Here, we describe the effects on epileptic seizures of encapsulated c
Externí odkaz:
https://doaj.org/article/3358439482c54be997637622f1eff5a7
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 10145 (2021)
Tau plays a central role in a group of neurodegenerative disorders collectively named tauopathies. Despite the wide range of diverse symptoms at the onset and during the progression of the pathology, all tauopathies share two common hallmarks, namely
Externí odkaz:
https://doaj.org/article/7e48cc7a025d47328229a152192454c5
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 16, p 5624 (2020)
Many studies have revealed a central role of p38 MAPK in neuronal plasticity and the regulation of long-term changes in synaptic efficacy, such as long-term potentiation (LTP) and long-term depression (LTD). However, p38 MAPK is classically known as
Externí odkaz:
https://doaj.org/article/858ec8d2f76048ab9ce13d4539d1fde0
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Externí odkaz:
https://doaj.org/article/d03f11d92174466da3ef3a7771b2122e
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
One third of the epilepsies are refractory to conventional antiepileptic drugs (AEDs) and, therefore, identification of new therapies is highly needed. Here, we briefly describe two approaches, direct cell grafting and gene therapy, that may represen
Externí odkaz:
https://doaj.org/article/8f01aa6e22e742b18ffe6a6727dcbd28
Autor:
Chiara Falcicchia, Pascal Trempat, Anna Binaschi, Coline Perrier-Biollay, Paolo Roncon, Marie Soukupova, Hervé Berthommé, Michele Simonato
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150995 (2016)
Brain-derived neurotrophic factor (BDNF) has been found to produce pro- but also anti-epileptic effects. Thus, its validity as a therapeutic target must be verified using advanced tools designed to block or to enhance its signal. The aim of this stud
Externí odkaz:
https://doaj.org/article/9c4693c71541459bbc643dd091feed61
Autor:
Andrea Buzzi, Maia Chikhladze, Chiara Falcicchia, Beatrice Paradiso, Giovanni Lanza, Marie Soukupova, Matteo Marti, Michele Morari, Silvana Franceschetti, Michele Simonato
Publikováno v:
Neurobiology of Disease, Vol 47, Iss 2, Pp 216-224 (2012)
Unverricht–Lundborg disease (ULD) is the most common progressive myoclonic epilepsy. Its etiology has been identified in a defect of a protease inhibitor, cystatin B (CSTB), but the mechanism(s) by which this defect translates in the clinical manif
Externí odkaz:
https://doaj.org/article/27121aa71ec741b5bb6ae43583b21100