Computational modelling of chromosomally clustering protein domains in bacteria

Autor: Chiara E. Cotroneo, Isobel Claire Gormley, Denis C. Shields, Michael Salter-Townshend

Publikováno v: BMC Bioinformatics, Vol 22, Iss 1, Pp 1-27 (2021)

Abstract Background In bacteria, genes with related functions—such as those involved in the metabolism of the same compound or in infection processes—are often physically close on the genome and form groups called clusters. The enrichment of such

Externí odkaz: https://doaj.org/article/67c196cdc118465bb4c4b689327061ce

Human Lung Tissue Transcriptome: Influence of Sex and Age.

Autor: Matteo Dugo, Chiara E Cotroneo, Emilie Lavoie-Charland, Matteo Incarbone, Luigi Santambrogio, Lorenzo Rosso, Maarten van den Berge, David Nickle, Peter D Paré, Yohan Bossé, Tommaso A Dragani, Francesca Colombo

Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0167460 (2016)

Sex and age strongly influence the pathophysiology of human lungs, but scarce information is available about their effects on pulmonary gene expression.We followed a discovery-validation strategy to identify sex- and age-related transcriptional diffe

Externí odkaz: https://doaj.org/article/730f9ecf9f5c484a9c0bc521d0c1e3c9

Lung expression of genes encoding SARS-CoV-2 cell entry molecules and antiviral restriction factors: interindividual differences are associated with age and germline variants

Autor: Tommaso A. Dragani, Francesca Colombo, Chiara E. Cotroneo, Nunzia Mangano

Germline variants in genes involved in SARS-CoV-2 cell entry (i.e. ACE2 and TMPRSS2) may influence the susceptibility to infection, as may polymorphisms in genes involved in the innate host response to viruses (e.g. APOBEC3 family). We searched for p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f0c003af884499b9c66fd571b8b7c2c
https://doi.org/10.1101/2020.06.24.168534

Genetic susceptibility variants for lung cancer: replication study and assessment as expression quantitative trait loci

Autor: Lorena Citterio, Matteo Dugo, Chiara E. Cotroneo, Tommaso A. Dragani, Paolo Manunta, Matteo Incarbone, Francesca Colombo, Luigi Santambrogio, Simona Delli Carpini, Giulia Pintarelli, Antonella Galvan, Davide Tosi, Sara Noci

Publikováno v: Scientific reports (Nature Publishing Group) 7 (2017). doi:10.1038/srep42185
info:cnr-pdr/source/autori:Pintarelli, Giulia; Cotroneo, Chiara Elisabetta; Noci, Sara; Dugo, Matteo; Galvan, Antonella; Delli Carpini, Simona; Citterio, Lorena; Manunta, Paolo; Incarbone, Matteo; Tosi, Davide; Santambrogio, Luigi; Dragani, Tommaso A.; Colombo, Francesca/titolo:Genetic susceptibility variants for lung cancer: Replication study and assessment as expression quantitative trait loci/doi:10.1038%2Fsrep42185/rivista:Scientific reports (Nature Publishing Group)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:7
Scientific Reports

Many single nucleotide polymorphisms (SNPs) have been associated with lung cancer but lack confirmation and functional characterization. We retested the association of 56 candidate SNPs with lung adenocarcinoma risk and overall survival in a cohort o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71a1745b4441c9921d688804c6802751
https://doi.org/10.1038/srep42185

Human Lung Tissue Transcriptome

Autor: David C. Nickle, Maarten van den Berge, Tommaso A. Dragani, Matteo Incarbone, Chiara E. Cotroneo, Peter D. Paré, Lorenzo Rosso, Emilie Lavoie-Charland, Yohan Bossé, Matteo Dugo, Francesca Colombo, Luigi Santambrogio

Publikováno v: PLoS ONE, 11(11):e0167460. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 11, Iss 11, p e0167460 (2016)
PloS one 11 (2016). doi:10.1371/journal.pone.0167460
info:cnr-pdr/source/autori:Dugo, Matteo; Cotroneo, Chiara E.; Lavoie-Charland, Emilie; Incarbone, Matteo; Santambrogio, Luigi; Rosso, Lorenzo; Van Den Berge, Maarten; Nickle, David; Paré, Peter D.; Bossé, Yohan; Dragani, Tommaso A.; Colombo, Francesca/titolo:Human lung tissue transcriptome: Influence of sex and age/doi:10.1371%2Fjournal.pone.0167460/rivista:PloS one/anno:2016/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
PLoS ONE

BackgroundSex and age strongly influence the pathophysiology of human lungs, but scarce information is available about their effects on pulmonary gene expression.MethodsWe followed a discovery-validation strategy to identify sex-and age-related trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfbc8c0fe833a3f792079b58e860225
https://hdl.handle.net/11370/e52e2116-007c-4581-a1a0-2bdff57eca57