Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Chiara Cirelli"'
Autor:
Rong Mao, Matias Lorenzo Cavelli, Graham Findlay, Kort Driessen, Michael J. Peterson, William Marshall, Giulio Tononi, Chiara Cirelli
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109919- (2024)
Summary: The cerebral cortex is widely considered part of the neural substrate of consciousness, but direct causal evidence is missing. Here, we tested in mice whether optogenetic activation of cortical neurons in posterior parietal cortex (PtA) or m
Externí odkaz:
https://doaj.org/article/220a3a0605734b81bed3b1c8f00f96de
Autor:
Chiara Cirelli, Giulio Tononi
Publikováno v:
Clinical and Translational Neuroscience, Vol 8, Iss 1, p 9 (2024)
When we are asleep, we lose the ability to promptly respond to external stimuli, and yet we spend many hours every day in this inherently risky behavioral state. This simple fact strongly suggests that sleep must serve essential functions that rely o
Externí odkaz:
https://doaj.org/article/925380e5112f4ef88061ae6ddfee9469
Publikováno v:
Journal of Integrative Neuroscience, Vol 23, Iss 1, p 24 (2024)
Objective: Absence seizures result from aberrant thalamocortical processing that confers synchronous, bilateral spike-and-wave discharges (SWDs) and behavioral arrest. Previous work has demonstrated that SWDs can result from enhanced thalamic tonic i
Externí odkaz:
https://doaj.org/article/b3a2273d255748bb8265161aa0270358
Autor:
Sophia S Loschky, Giovanna Maria Spano, William Marshall, Andrea Schroeder, Kelsey Marie Nemec, Shannon Sandra Schiereck, Luisa de Vivo, Michele Bellesi, Sebastian Weyn Banningh, Giulio Tononi, Chiara Cirelli
Publikováno v:
eLife, Vol 11 (2022)
Multiple evidence in rodents shows that the strength of excitatory synapses in the cerebral cortex and hippocampus is greater after wake than after sleep. The widespread synaptic weakening afforded by sleep is believed to keep the cost of synaptic ac
Externí odkaz:
https://doaj.org/article/19124e3371cf4ca8b43a93db043b81fb
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The synaptic mechanisms of how sleep benefits cognitive functions are not well characterised. Here, the authors show that sleep leads to an overall net decrease in spine-surface GluA1-containing AMPA receptors and that this is correlated with changes
Externí odkaz:
https://doaj.org/article/d529df96f491401a996ef22ddfdcb130
Autor:
Serena Ricci, Elisa Tatti, Aaron B. Nelson, Priya Panday, Henry Chen, Giulio Tononi, Chiara Cirelli, M. Felice Ghilardi
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
We have previously demonstrated that, in rested subjects, extensive practice in a motor learning task increased both electroencephalographic (EEG) theta power in the areas involved in learning and improved the error rate in a motor test that shared s
Externí odkaz:
https://doaj.org/article/5be035211692474a9f9077681f7ec1ab
Autor:
Elisa Tatti, Serena Ricci, Aaron B. Nelson, Dave Mathew, Henry Chen, Angelo Quartarone, Chiara Cirelli, Giulio Tononi, Maria Felice Ghilardi
Publikováno v:
Frontiers in Systems Neuroscience, Vol 14 (2020)
Beta oscillations (13.5−25 Hz) over the sensorimotor areas are characterized by a power decrease during movement execution (event-related desynchronization, ERD) and a sharp rebound after the movement end (event-related synchronization, ERS). In pr
Externí odkaz:
https://doaj.org/article/f2307bfc12724b2b9f443a36d38257fc
Autor:
Allen K. Bourdon, Giovanna Maria Spano, William Marshall, Michele Bellesi, Giulio Tononi, Pier Andrea Serra, Helen A. Baghdoyan, Ralph Lydic, Shawn R. Campagna, Chiara Cirelli
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Abstract By identifying endogenous molecules in brain extracellular fluid metabolomics can provide insight into the regulatory mechanisms and functions of sleep. Here we studied how the cortical metabolome changes during sleep, sleep deprivation and
Externí odkaz:
https://doaj.org/article/a457f0f7191f427aa96a87048d92199f
Regulation of cortical activity and arousal by the matrix cells of the ventromedial thalamic nucleus
Autor:
Sakiko Honjoh, Shuntaro Sasai, Shannon S Schiereck, Hirotaka Nagai, Giulio Tononi, Chiara Cirelli
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The ventromedial thalamus (VM) is thought to control cortical arousal through its diffuse projections to cortex. Here the authors record and manipulate the activity of calbindin1-positive matrix cells in VM and show that they bidirectionally regulate
Externí odkaz:
https://doaj.org/article/115632674bd341c7b8022f925c0b2529
Publikováno v:
Genomics Data, Vol 6, Iss C, Pp 114-117 (2015)
Transcriptomic studies revealed that hundreds of mRNAs show differential expression in the brains of sleeping relative to awake rats, mice, flies, and sparrows. Although these results have offered clues regarding the molecular consequences of sleep a
Externí odkaz:
https://doaj.org/article/fc02a28f0132466490195cad803002ef