Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chiara Carla Rospo"'
Autor:
Elizabeth S Hickford, James O'Connell, Alison Maloney, Peter Florian, Geoffrey I Johnston, Chiara Carla Rospo, Matthias Herrmann, Sara Wright, Tim Bourne
Publikováno v:
Bioanalysis. 15:343-359
Background: An antibody specific to small-molecule inhibitor-bound TNF has enabled the development of target occupancy biomarker assays to support the development of novel treatments for autoimmune disorders. Materials & methods: ELISAs were develope
Publikováno v:
Bioanalysis. 13(21)
As the number of therapeutic modalities expand, and the field of scientific research evolves toward finding treatment solutions for complex and rare disease, an ability to demonstrate efficacy through biomarker end points in clinical development stud
Autor:
Yves Lamberty, Marie-Christine Tordeur, Chiara Carla Rospo, Michael V. Accardi, François Bouzom, Karine Leclercq, Martyn D. Wood, Simon Hebeisen, Véronique M. André, Annie Delaunois, Simon Authier, Jean-Pierre Valentin, Faiza Laredj, Marie-Luce Rosseels, Anne-Gaëlle Letombe
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 104:106874
Introduction Several compounds from a neuroscience project induced convulsions in animals, at low exposure levels via a hypothetical off-target mechanism. A set of in vitro and in vivo experiments were conducted in order to 1) identify the mechanism
Autor:
Karine Leclercq, Chiara Carla Rospo, Ann Van Eeckhaut, An De Prins, Camila V. Esguerra, Olivia Erin M Buenafe, Mélanie Langlois, Rafal M. Kaminski, Ilse Julia Smolders, Alexander D. Crawford, Tatiana Afrikanova, Peter de Witte
Publikováno v:
Epilepsy & behavior : E&B, 45, 53-63. United States (2015).
Treatment-resistant seizures affect about a third of patients suffering from epilepsy. To fulfill the need for new medications targeting treatment-resistant seizures, a number of rodent models offer the opportunity to assess a variety of potential tr
Publikováno v:
Experimental Neurology. 238:156-167
Temporal lobe epilepsy (TLE) is the most common form of drug-resistant epilepsy and several rodent models allow studying the pathophysiology of this disorder. One of the best characterized models of TLE is the pilocarpine model. The model has been wi
Autor:
Martyn D. Wood, Véronique M. André, Faiza Laredj, Jean-Pierre Valentin, Simon Authier, Annie Delaunois, François Bouzom, Michael V. Accardi, Chiara Carla Rospo
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 93:108
Autor:
Delphine Parachou, Christophe Drieu La Rochelle, Ludovicus Staelens, Annie Delaunois, Massimo Fonsi, Chiara Carla Rospo, Eric Delpy, Anthony Deal
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:e4-e5
Autor:
Eric Delpy, Anne-Marie Betat, Ludovicus Staelens, Annie Delaunois, Christophe Drieu La Rochelle, Aurore Colomar, Chiara Carla Rospo
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 70:335