Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Chiara Bruckmann"'
Autor:
Sara Isernia, Valeria Blasi, Gisella Baglio, Monia Cabinio, Pietro Cecconi, Federica Rossetto, Marta Cazzoli, Francesco Blasi, Chiara Bruckmann, Fabrizio Giunco, Sandro Sorbi, Mario Clerici, Francesca Baglio
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundThe age-related decrease in reserve and resistance to stressors is recognized as frailty, one of the most significant challenges identified in recent years. Despite a well-acknowledged association of frailty with cognitive impairment, depre
Externí odkaz:
https://doaj.org/article/3a988a38e4f44cce8281c0c55bbf5768
Autor:
Francesco Blasi, Chiara Bruckmann
Publikováno v:
Journal of Developmental Biology, Vol 9, Iss 4, p 44 (2021)
Recently MEIS1 emerged as a major determinant of the MLL-r leukemic phenotype. The latest and most efficient drugs effectively decrease the levels of MEIS1 in cancer cells. Together with an overview of the latest drugs developed to target MEIS1 in ML
Externí odkaz:
https://doaj.org/article/7d8dcc5c4e3046dca1fe6c294a3aa6e3
Autor:
Chiara Bruckmann, Endre Sebestyén
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 8, p e1005664 (2017)
Externí odkaz:
https://doaj.org/article/bf59452ae0b244958421fc5fac1b4c4d
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125789 (2015)
Human PREP1 and PBX1 are homeodomain transcriptional factors, whose biochemical and structural characterization has not yet been fully described. Expression of full-length recombinant PREP1 (47.6 kDa) and PBX1 (46.6 kDa) in E. coli is difficult becau
Externí odkaz:
https://doaj.org/article/f781c071dfbb4f448c7ba9f552f1bfa2
Autor:
Francesca D'Addio, Laura Montefusco, Maria Elena Lunati, Ida Pastore, Emma Assi, Adriana Petrazzuolo, Virna Marin, Chiara Bruckmann, Paolo Fiorina
Publikováno v:
BioEssays. 45
Autor:
Samir Hassoun, Chiara Bruckmann, Stefano Ciardullo, Gianluca Perseghin, Francesca Di Gaudio, Francesco Broccolo
Background: The progress of digital transformation in clinical practice opens the door to transforming the current clinical line for liver disease diagnosis from a late-stage diagnosis approach to an early-stage based one. Early diagnosis of liver fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b84169a7324500c7db8dbf7da084f4
https://hdl.handle.net/10447/584194
https://hdl.handle.net/10447/584194
Autor:
Samir Hassoun, Chiara Bruckmann, Stefano Ciardullo, Gianluca Perseghin, Francesca Di Gaudio, Francesco Broccolo
Publikováno v:
SSRN Electronic Journal.
Autor:
Alessandra, Monti, Chiara, Bruckmann, Francesco, Blasi, Menotti, Ruvo, Luigi, Vitagliano, Nunzianna, Doti
Publikováno v:
Chemical communications (Cambridge, England). 57(30)
PREP1-based peptides form amyloid-like aggregates endowed with an intrinsic blue-green-red fluorescence with an unusual sharp maximum at 520 nm upon excitation with visible light under physiological conditions. The peptide PREP1[117-132], whose seque
Autor:
Francesco Blasi, Valentina De Lorenzi, Simone Tamburri, Menotti Ruvo, Alessandra Monti, Angela Bachi, Lisa Mathiasen, Angela Cattaneo, Nunzianna Doti, Chiara Bruckmann
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports
Scientific Reports
Both onco-suppressor PREP1 and the oncogene MEIS1 bind to PBX1. This interaction stabilizes the two proteins and allows their translocation into the nucleus and thus their transcriptional activity. Here, we have combined cross-linking mass-spectromet
Autor:
Luigi Vitagliano, Chiara Bruckmann, Andrea Caporale, Menotti Ruvo, Luisa Calvanese, Gabriella D'Auria, Nunzianna Doti, Giovanni Smaldone, Lucia Falcigno, Alessandra Monti, Francesco Blasi
The ability of many proteins to fold into well-defined structures has been traditionally considered a prerequisite for fulfilling their functions. Protein folding is also regarded as a valuable loophole to escape uncontrolled and harmful aggregations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40566954f506ad96504f2d733e5e689c
http://hdl.handle.net/11588/814043
http://hdl.handle.net/11588/814043