Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Chiara Bigogno"'
Autor:
Cristina Cigana, Ruggero Giannella, Alice Colavolpe, Beatriz Alcalá-Franco, Giulia Mancini, Francesca Colombi, Chiara Bigogno, Ulla Bastrup, Giovanni Bertoni, Alessandra Bragonzi
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Cystic fibrosis transmembrane conductance regulator (CFTR) modulators improve clinical outcomes with varied efficacies in patients with CF. However, the mutual effects of CFTR modulators and bacterial adaptation, together with antibiotic reg
Externí odkaz:
https://doaj.org/article/6947943a288f47d58320b4121f5e4c15
Autor:
Anna Tesei, Michela Cortesi, Sara Pignatta, Chiara Arienti, Giulio Massimo Dondio, Chiara Bigogno, Alessio Malacrida, Mariarosaria Miloso, Cristina Meregalli, Alessia Chiorazzi, Valentina Carozzi, Guido Cavaletti, Marta Rui, Annamaria Marra, Daniela Rossi, Simona Collina
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Introduction: Pancreatic cancer (PC) is one of the most lethal tumor worldwide, with no prognosis improvement over the past 20-years. The silent progressive nature of this neoplasia hampers the early diagnosis, and the surgical resection of the tumor
Externí odkaz:
https://doaj.org/article/e889e8abc8fa45a8a8c6a8d1b9b52103
Autor:
Nicoletta Basilico, Silvia Parapini, Anna Sparatore, Sergio Romeo, Paola Misiano, Livia Vivas, Vanessa Yardley, Simon L. Croft, Annette Habluetzel, Leonardo Lucantoni, Laurent Renia, Bruce Russell, Rossarin Suwanarusk, Francois Nosten, Giulio Dondio, Chiara Bigogno, Daniela Jabes, Donatella Taramelli
Publikováno v:
Molecules, Vol 22, Iss 12, p 2102 (2017)
Natural products are a prolific source for the identification of new biologically active compounds. In the present work, we studied the in vitro and in vivo antimalarial efficacy and ADME-Tox profile of a molecular hybrid (AM1) between 4-aminoquinoli
Externí odkaz:
https://doaj.org/article/109aa3a57b6d49ebb3938d568b370008
Autor:
Marianna Bufano, Michela Puxeddu, Marianna Nalli, Giuseppe La Regina, Angelo Toto, Francesca Romana Liberati, Alessio Paone, Francesca Cutruzzolà, Domiziana Masci, Chiara Bigogno, Giulio Dondio, Romano Silvestri, Stefano Gianni, Antonio Coluccia
Publikováno v:
Bioorganic Chemistry. 138:106607
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afec4cc73e2a1397ba1631af84ee4a84
https://doi.org/10.1016/j.bioorg.2023.106607
https://doi.org/10.1016/j.bioorg.2023.106607
Autor:
Jessica Sebastiani, Michela Puxeddu, Marianna Nalli, Ruoli Bai, Ludovica Altieri, Paola Rovella, Eugenio Gaudio, Daniela Trisciuoglio, Filippo Spriano, Patrizia Lavia, Cinzia Fionda, Domiziana Masci, Andrea Urbani, Chiara Bigogno, Giulio Dondio, Ernest Hamel, Francesco Bertoni, Romano Silvestri, Giuseppe La Regina
We synthesized a new inhibitor of tubulin polymerization, the pyrrole (1-(7H-pyrrolo[2,3- d]pyrimidin-4-yl)-1H-pyrrol-3-yl)(3,4,5-trimethoxy-phenyl)methanone 6 (RS6077). Compound 6 inhibited the growth of multiple cancer cell lines, with IC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b627b1f33ba1c80296963a7e5f365b5c
https://hdl.handle.net/11573/1669754
https://hdl.handle.net/11573/1669754
Autor:
Michela Puxeddu, Jianchao Wu, Ruoli Bai, Michele D’Ambrosio, Marianna Nalli, Antonio Coluccia, Simone Manetto, Alessia Ciogli, Domiziana Masci, Andrea Urbani, Cinzia Fionda, Sonia Coni, Rosa Bordone, Gianluca Canettieri, Chiara Bigogno, Giulio Dondio, Ernest Hamel, Te Liu, Romano Silvestri, Giuseppe La Regina
Publikováno v:
Journal of medicinal chemistry. 65(23)
We synthesized new aroyl diheterocyclic pyrrole (ARDHEP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e537297ba1d657b358721ec95924b69
https://pubmed.ncbi.nlm.nih.gov/36395526
https://pubmed.ncbi.nlm.nih.gov/36395526
Autor:
Mario Saletti, Samuele Maramai, Annalisa Reale, Marco Paolino, Simone Brogi, Angela Di Capua, Andrea Cappelli, Gianluca Giorgi, Danilo D'Avino, Antonietta Rossi, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Roccaldo Sardella, Andrea Carotti, Gerald Woelkart, Burkhard Klösch, Chiara Bigogno, Giulio Dondio, Maurizio Anzini
Publikováno v:
European journal of medicinal chemistry. 241
The design of compounds able to combine the selective inhibition of cyclooxygenase-2 (COX-2) with the release of nitric oxide (NO) is a promising strategy to achieve potent anti-inflammatory agents endowed with an overall safer profile and reduced to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd9ad58bbfe8e7adff66bdb69561884
https://pubmed.ncbi.nlm.nih.gov/35932568
https://pubmed.ncbi.nlm.nih.gov/35932568
Autor:
Lorenzo Taiarol, Chiara Bigogno, Silvia Sesana, Marcelo Kravicz, Francesca Viale, Eleonora Pozzi, Laura Monza, Valentina Alda Carozzi, Cristina Meregalli, Silvia Valtorta, Rosa Maria Moresco, Marcus Koch, Federica Barbugian, Laura Russo, Giulio Dondio, Christian Steinkühler, Francesca Re
Publikováno v:
Cancers (Basel) 14 (2022): 2978. doi:10.3390/cancers14122978
info:cnr-pdr/source/autori:Taiarol L.; Bigogno C.; Sesana S.; Kravicz M.; Viale F.; Pozzi E.; Monza L.; Carozzi V.A.; Meregalli C.; Valtorta S.; Moresco R.M.; Koch M.; Barbugian F.; Russo L.; Dondio G.; Steinkühler C.; Re F./titolo:Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and Pharmacokinetics/doi:10.3390%2Fcancers14122978/rivista:Cancers (Basel)/anno:2022/pagina_da:2978/pagina_a:/intervallo_pagine:2978/volume:14
Cancers; Volume 14; Issue 12; Pages: 2978
info:cnr-pdr/source/autori:Taiarol L.; Bigogno C.; Sesana S.; Kravicz M.; Viale F.; Pozzi E.; Monza L.; Carozzi V.A.; Meregalli C.; Valtorta S.; Moresco R.M.; Koch M.; Barbugian F.; Russo L.; Dondio G.; Steinkühler C.; Re F./titolo:Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and Pharmacokinetics/doi:10.3390%2Fcancers14122978/rivista:Cancers (Basel)/anno:2022/pagina_da:2978/pagina_a:/intervallo_pagine:2978/volume:14
Cancers; Volume 14; Issue 12; Pages: 2978
Glioblastoma is the most common and aggressive brain tumor, associated with poor prognosis and survival, representing a challenging medical issue for neurooncologists. Dysregulation of histone-modifying enzymes (HDACs) is commonly identified in many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a555b1f33e78aa598374bdf6a13ff1aa
https://pubmed.ncbi.nlm.nih.gov/35740641
https://pubmed.ncbi.nlm.nih.gov/35740641
Autor:
Cristina Cigana, Ruggero Giannella, Alice Colavolpe, Beatriz Alcalá-Franco, Giulia Mancini, Colombi Francesca, Chiara Bigogno, Ulla Bastrup, Giovanni Bertoni, Alessandra Bragonzi
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators improve clinical outcomes with variable efficacy in patients with cystic fibrosis (CF). However, changes produced by bacterial persistence and adaptation in addition to antibiotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdaef65e5f79dc9c86d42e8a3da652a1
https://doi.org/10.1101/2022.02.15.478594
https://doi.org/10.1101/2022.02.15.478594
Autor:
Chiara Bigogno, Alessia Chiorazzi, Valentina Alda Carozzi, Marta Rui, Annamaria Marra, Sara Pignatta, Guido Cavaletti, Simona Collina, Cristina Meregalli, Giulio Dondio, Chiara Arienti, Mariarosaria Miloso, Anna Tesei, Alessio Malacrida, Michela Cortesi, Daniela Rossi
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology, Vol 10 (2019)
Introduction: Pancreatic cancer (PC) is one of the most lethal tumor worldwide, with no prognosis improvement over the past 20-years. The silent progressive nature of this neoplasia hampers the early diagnosis, and the surgical resection of the tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1778ba40b61afb227589d31dbc64646
http://hdl.handle.net/10281/261068
http://hdl.handle.net/10281/261068