Výsledky vyhledávání - "Chiara Astrua"

Isolation of extracellular vesicles improves the detection of mutant DNA from plasma of metastatic melanoma patients

Autor: Antonio Chiesi, Francesco M. Carpi, Maria Teresa Fierro, Chiara Astrua, Pietro Quaglino, Simona Bernardi, Chiara Foroni, Paolo Fava, Domenico Russo, Laura Bianciardi, Mauro Novelli, Ottavia Malavenda, Natasa Zarovni, Davide Zocco

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports

Detection of BRAFV600E within cell free tumor DNA (ctDNA) is emerging as a promising means to improve patients’ stratification or enable BRAF inhibitor (BRAFi) therapeutic monitoring in a minimally invasive manner. Here, we investigated whether ext

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b24c69230a74678cee16ea40046e0740
http://link.springer.com/article/10.1038/s41598-020-72834-6

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CD38 Expression by Circulating and Skin-Infiltrating Lymphocytes from Sezary Syndrome Patients: A Flow Cytometry and Immunohistochemistry Study

Autor: Pietro Quaglino, Mauro Novelli, Paolo Fava, Erika Ortolan, Chiara Astrua, Luca Tonella, Carlo Francesco Tomasini, Rebecca Senetta, Simone Ribero, Renata Ponti, Maria Teresa Fierro, Ada Funaro

Background. Reports on the expression of CD38 in Sézary syndrome (SS), erythrodermic primary cutaneous T cell lymphoma with leukemic involvement, are limited. The aim of the present study is the analysis of the expression of CD38 by skin-infiltratin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50474a2af8aceba081fedfee88b80e51
http://hdl.handle.net/2318/1858942

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BRAFi/MEKi in patients with metastatic melanoma: predictive factors of complete response

Autor: Maria Teresa Fierro, Virginia Caliendo, Simone Ribero, Simona Osella-Abate, Martina Sanlorenzo, Ottavia Malavenda, Pietro Quaglino, Paolo Fava, Chiara Astrua, Elena Marra

Publikováno v: Future Oncology. 15:133-139

Aim: A survival benefit was demonstrated by dabrafenib + trametinib for metastatic BRAF-mutated melanoma patients. Best response is a strong prognostic marker for survival. Patients & methods: The specific features associated with complete response (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5fa36af49f03985cb916fae76f51f9f
https://doi.org/10.2217/fon-2018-0386

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Phenotypical Markers, Molecular Mutations, and Immune Microenvironment as Targets for New Treatments in Patients with Mycosis Fungoides and/or Sézary Syndrome

Autor: Vieri Grandi, Paolo Fava, Maarten H. Vermeer, Emilio Berti, Luca Tonella, Marco Rubatto, Silvia Alberti-Violetti, Alessandro Pileri, Martina Sanlorenzo, Mauro Novelli, Julia Scarisbrick, Alba Guglielmo, Maria Teresa Fierro, Nicola Pimpinelli, Pietro Quaglino, Simone Ribero, Vincenzo Panasiti, Simona Osella Abate, Chiara Astrua

Publikováno v: Journal of Investigative Dermatology, 141(3), 484-495. ELSEVIER SCIENCE INC

Primary cutaneous lymphomas encompass a wide spectrum of rare lymphoproliferative disorders originating in the skin, among which, mycosis fungoides (MF) is the most common subtype. The treatment of this disease is based on skin-directed therapies eve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c30776d05ea002c80970506019a6049
http://hdl.handle.net/2318/1768581

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Arrhythmias in a patient with metastatic melanoma treated with targeted therapy and implantable cardioverter defibrillator

Autor: V. Contu, Matteo Licciardello, Giulia Rozzo, Chiara Astrua, M.T. Fierro, Simone Ribero, Paolo Fava, P. Lista, Elena Marra, Pietro Quaglino, Maria Teresa Giura

Publikováno v: British Journal of Dermatology. 177:584-587

Metastatic melanoma is an aggressive and rapidly progressive disease. Heart metastases were shown in over 50% of autopsy. However, these metastases are usually clinically silent and reported in less than 2% of living patients1.2. There are no specifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c98dd196d9067fe4699ee1671fd61a69
https://doi.org/10.1111/bjd.15447

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Ipilimumab (Anti-Ctla-4 Mab) in the treatment of metastatic melanoma: Effectiveness and toxicity management

Autor: Paolo Fava, Chiara Astrua, Paola Savoia

Publikováno v: Human Vaccines & Immunotherapeutics. 12:1092-1101

In the last years the onset of new therapies changed the management of malignant melanoma. Anti CTLA-4 antibody ipilimumab was the first drug to achieve a significant improvement in survival of advanced stage melanoma. This new therapeutic agent is c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99312d12d8a880283f39f7c01bac7dff
https://doi.org/10.1080/21645515.2015.1129478

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Human Endogenous Retrovirus Expression in Primary Cutaneous T-Cell Lymphomas

Autor: Pier-Angelo Tovo, Ilaria Galliano, Maria Teresa Fierro, Paola Montanari, Massimiliano Bergallo, Matteo Brizio, Chiara Astrua, Paola Savoia, Paolo Fava, Mauro Novelli, Pietro Quaglino

Publikováno v: Dermatology. 232:38-43

Background: Mycosis fungoides (MF) and Sézary syndrome (SS) are the most frequent cutaneous T-cell lymphomas (CTCL). Human endogenous retroviruses (HERVs) were reverse transcribed and integrated into primate chromosomal DNA, becoming noninfectious,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56ceb63eae2dda095a2bde732e88a2f
https://doi.org/10.1159/000438669

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