Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Chiara, Montemurro"'
Autor:
Chiara Montemurro, Hiroshi Nomoto, Lina Pei, Vishal S. Parekh, Kenny E. Vongbunyong, Suryakiran Vadrevu, Tatyana Gurlo, Alexandra E. Butler, Rohan Subramaniam, Eleni Ritou, Orian S. Shirihai, Leslie S. Satin, Peter C. Butler, Slavica Tudzarova
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Type 2 diabetes is associated with islet amyloid deposits derived from islet amyloid polypeptide (IAPP) expressed by β-cells. Here the authors show that IAPP misfolded protein stress induces the hypoxia inducible factor 1 alpha injury repair pathway
Externí odkaz:
https://doaj.org/article/386002cb2bd14399b8b10d3e7c881ca5
Autor:
Abu Saleh Md Moin, Chiara Montemurro, Kylie Zeng, Megan Cory, Megan Nguyen, Shweta Kulkarni, Helga Fritsch, Juris J. Meier, Sangeeta Dhawan, Robert A. Rizza, Mark A. Atkinson, Alexandra E. Butler
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2019)
Context: Previously, we identified chromograninA positive hormone-negative (CPHN) cells in high frequency in human fetal and neonatal pancreas, likely representing nascent endocrine precursor cells. Here, we characterize the putative endocrine fate a
Externí odkaz:
https://doaj.org/article/a8a03cdfe8ed4da0a5482930e7c4379e
Autor:
Chiara Montemurro, Hiroshi Nomoto, Lina Pei, Vishal S. Parekh, Kenny E. Vongbunyong, Suryakiran Vadrevu, Tatyana Gurlo, Alexandra E. Butler, Rohan Subramaniam, Eleni Ritou, Orian S. Shirihai, Leslie S. Satin, Peter C. Butler, Slavica Tudzarova
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/f101ba5ab0584a34acbce56d3c598de5
Autor:
Giovanni Coppola, Allison E. Furterer, Hiroshi Nomoto, Chiara Montemurro, Brian B. Nadel, Peter C. Butler, Tatyana Gurlo, Madeline Rosenberger, Lina Pei, Matteo Pellegrini, Slavica Tudzarova
Publikováno v:
Diabetologia, vol 63, iss 1
Diabetologia
Diabetologia
AIMS/HYPOTHESIS: The conserved hypoxia inducible factor 1 α (HIF1α) injury-response pro-survival pathway has recently been implicated in early beta cell dysfunction but slow beta cell loss in type 2 diabetes. We hypothesised that the unexplained pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa91163be5a899bc4054894542abda9
https://escholarship.org/uc/item/3bp8j6v6
https://escholarship.org/uc/item/3bp8j6v6
Autor:
Andrea Tannapfel, Waldemar Uhl, Juris J. Meier, Sandra Ueberberg, Michael A. Nauck, Chiara Montemurro, Anne Clark
Publikováno v:
The Journal of clinical endocrinology and metabolism. 105(8)
Background Amyloid deposits are a typical finding in pancreatic islets from patients with type 2 diabetes. Whether this is linked to the pathogenesis of type 2 diabetes is currently unknown. Therefore, we compared the occurrence of islet amyloid in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48c60636779fba7ad99226685e361d1
https://pubmed.ncbi.nlm.nih.gov/32271378
https://pubmed.ncbi.nlm.nih.gov/32271378
Autor:
Chiara Montemurro, Yumi Yokoyama, Heather R. Christofk, Aaron Lisberg, Robert Wild, Morgan Brady, Margaret Dugan, Milica Momcilovic, David B. Shackelford, Katerina Politi
Publikováno v:
Cancer Research. 81:1572-1572
Recent breakthroughs with checkpoint inhibitors (CPI) or the third generation tyrosine kinase inhibitor (TKI) osimertinib (OSI) for patients with specific mutations to the epidermal growth factor receptor (EGFR) gene are now able to induce durable re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3c107d7ed8c1fe8e3991dc7ae11c807
https://doi.org/10.1158/1538-7445.am2021-1572
https://doi.org/10.1158/1538-7445.am2021-1572
Autor:
Tatyana Gurlo, Slavica Tudzarova, Leslie S. Satin, Chiara Montemurro, Vishal S. Parekh, Suryakiran Vadrevu, Kenny E. Vongbunyong, Hiroshi Nomoto, Peter C. Butler, Eleni Ritou, Rohan Subramaniam, Lina Pei, Orian S. Shirihai, Alexandra E. Butler
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The islet in type 2 diabetes (T2D) is characterized by amyloid deposits derived from islet amyloid polypeptide (IAPP), a protein co-expressed with insulin by β-cells. In common with amyloidogenic proteins implicated in neurodegeneration, human IAPP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39036595ad62f5b5d3855b2bc46bd7d6
http://europepmc.org/articles/PMC6581914
http://europepmc.org/articles/PMC6581914
Autor:
Sarah M. Dry, Aleksey V. Matveyenko, Tatyana Gurlo, David Kirakossian, Chiara Montemurro, Belinda Schludi, Abu Saleh Md Moin, David W. Dawson, Peter C. Butler, Alexandra E. Butler
Publikováno v:
JCI insight, vol 2, iss 13
Schludi, Belinda; Moin, Abu Saleh Md; Montemurro, Chiara; Gurlo, Tatyana; Matveyenko, Aleksey V; Kirakossian, David; et al.(2017). Islet inflammation and ductal proliferation may be linked to increased pancreatitis risk in type 2 diabetes. JCI INSIGHT, 2(13). doi: 10.1172/jci.insight.92282. UCLA: Retrieved from: http://www.escholarship.org/uc/item/0b19r9pp
Schludi, Belinda; Moin, Abu Saleh Md; Montemurro, Chiara; Gurlo, Tatyana; Matveyenko, Aleksey V; Kirakossian, David; et al.(2017). Islet inflammation and ductal proliferation may be linked to increased pancreatitis risk in type 2 diabetes. JCI INSIGHT, 2(13). doi: 10.1172/jci.insight.92282. UCLA: Retrieved from: http://www.escholarship.org/uc/item/0b19r9pp
Pancreatitis is more frequent in type 2 diabetes mellitus (T2DM), although the underlying cause is unknown. We tested the hypothesis that ongoing β cell stress and apoptosis in T2DM induces ductal tree proliferation, particularly the pancreatic duct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2171f21f7dc42386ba4e15c07e6392
https://doi.org/10.1172/jci.insight.92282
https://doi.org/10.1172/jci.insight.92282
Autor:
Daniel Braas, Kenny E. Vongbunyong, Anton Petcherski, Peter C. Butler, Tatyana Gurlo, Leslie S. Satin, Orian S. Shirihai, Suryakiran Vadrevu, Slavica Tudzarova, Alexandra E. Butler, Chiara Montemurro
Publikováno v:
Montemurro, C; Vadrevu, S; Gurlo, T; Butler, AE; Vongbunyong, KE; Petcherski, A; et al.(2017). Cell cycle-related metabolism and mitochondrial dynamics in a replication-competent pancreatic beta-cell line. CELL CYCLE, 16(21), 2086-2099. doi: 10.1080/15384101.2017.1361069. UCLA: Retrieved from: http://www.escholarship.org/uc/item/0zc4f2mv
Cell cycle (Georgetown, Tex.), vol 16, iss 21
Cell cycle (Georgetown, Tex.), vol 16, iss 21
Cell replication is a fundamental attribute of growth and repair in multicellular organisms. Pancreatic beta-cells in adults rarely enter cell cycle, hindering the capacity for regeneration in diabetes. Efforts to drive beta-cells into cell cycle hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d08b7b11d1eb85fb12848115102a92e
http://www.escholarship.org/uc/item/0zc4f2mv
http://www.escholarship.org/uc/item/0zc4f2mv
Autor:
Chiara Montemurro, P.P. Joazeiro, Kamila C. Silva, Daniel Teixeira, E. B. M. I. Peixoto, Diego Andreazzi Duarte, J. Lopes de Faria, Alexandros Papadimitriou, J. B. Lopes de Faria
Publikováno v:
The Journal of nutritional biochemistry. 26(4)
In diabetes mellitus (DM), podocyte apoptosis leads to albuminuria and nephropathy progression. Low-density lipoprotein receptor-related protein 6 (LRP6) is WNT pathway receptor that is involved in podocyte death, adhesion and motility. Glycogen synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f593460abe7efeefe2778acbea988a7
https://pubmed.ncbi.nlm.nih.gov/25655048
https://pubmed.ncbi.nlm.nih.gov/25655048