Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Chiara, Macchi"'
Autor:
Chiara Macchi, Andrea Giachi, Isabella Fichtner, Silvia Pedretti, Piercarlo Sarzi Puttini, Nico Mitro, Alberto Corsini, Massimiliano Ruscica, Roberta Gualtierotti
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Fibromyalgia is a musculoskeletal syndrome characterized by chronic widespread pain that is often associated with systemic manifestations. Since mitochondria are the main source of cellular energy, we hypothesized that fibromyalgia syndrome
Externí odkaz:
https://doaj.org/article/a04eac0d07654ccfa5bc302464a263b7
Autor:
Isabella Fichtner, Chiara Macchi, Alessandra Stefania Rizzuto, Stefano Carugo, Alberto Corsini, Massimiliano Ruscica
Publikováno v:
Atherosclerosis Plus, Vol 58, Iss , Pp 16-23 (2024)
The fact that lipoprotein(a) levels should be regarded as a causal residual risk factor in the atherosclerotic cardiovascular diseases (ASCVD) is now a no-brainer. This review article aims to summarize the latest evidence supporting the causal role o
Externí odkaz:
https://doaj.org/article/93b4bfd1e23b4b35bb2cc5556d535adc
Autor:
Alessandra Stefania Rizzuto, Guido Gelpi, Andrea Mangini, Stefano Carugo, Massimiliano Ruscica, Chiara Macchi
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109359- (2024)
Summary: Epicardial adipose tissue (EAT) is a fat depot located between the myocardium and the visceral layer of the epicardium, which, owing to its location, can influence surrounding tissues and can act as a local transducer of systemic inflammatio
Externí odkaz:
https://doaj.org/article/c094af31f5234aceaff811b31fae1774
Autor:
Massimiliano Ruscica, Chiara Macchi, Angelica Giuliani, Alessandra Stefania Rizzuto, Deborah Ramini, Matilde Sbriscia, Stefano Carugo, Anna Rita Bonfigli, Alberto Corsini, Fabiola Olivieri, Jacopo Sabbatinelli
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and mortality, being twofold to fourfold more common in patients with type 2 diabetes mellitus (T2DM) than in individuals without diabetes. However,
Externí odkaz:
https://doaj.org/article/e2246e443c07423f928752e55c832e6b
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Proprotein convertase subtilisin/kexin type 9 (PCSK9), one of the key regulators of the low-density lipoprotein receptor (LDLR), can play a direct role in atheroma development. Although advances in the understandings of genetic PCSK9 polymorphisms ha
Externí odkaz:
https://doaj.org/article/4b313c77549146b6bbfcde280189e69d
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102301- (2023)
Summary: The infiltration of activated T cells, such as CD8+ effector, in metabolic tissues plays a crucial role for the initiation and propagation of obesity-induced inflammation. Given the pivotal role of lactate transporter monocarboxylate transpo
Externí odkaz:
https://doaj.org/article/3a1584d9ee6546a68a6be061c8a11a41
Autor:
Chiara Macchi, Cesare R. Sirtori, Alberto Corsini, Pier Mannuccio Mannucci, Massimiliano Ruscica
Publikováno v:
Environment International, Vol 175, Iss , Pp 107923- (2023)
According to the WHO, the entire global population is exposed to air pollution levels higher than recommended for health preservation. Air pollution is a complex mixture of nano- to micro-sized particles and gaseous components that poses a major glob
Externí odkaz:
https://doaj.org/article/0eddda90e709447ebb39575a124fc027
Low Lipoprotein(a) Levels Predict Hepatic Fibrosis in Patients With Nonalcoholic Fatty Liver Disease
Autor:
Marica Meroni, Miriam Longo, Rosa Lombardi, Erika Paolini, Chiara Macchi, Alberto Corsini, Cesare R. Sirtori, Anna Ludovica Fracanzani, Massimiliano Ruscica, Paola Dongiovanni
Publikováno v:
Hepatology Communications, Vol 6, Iss 3, Pp 535-549 (2022)
Dyslipidemia and cardiovascular complications are comorbidities of nonalcoholic fatty liver disease (NAFLD), which ranges from simple steatosis to nonalcoholic steatohepatitis, fibrosis, and cirrhosis up to hepatocellular carcinoma. Lipoprotein(a) (L
Externí odkaz:
https://doaj.org/article/6940123c6db24737b71d62951ada2727
Autor:
Miriam Longo, Marica Meroni, Erika Paolini, Veronica Erconi, Fabrizia Carli, Francesco Fortunato, Dario Ronchi, Roberto Piciotti, Silvia Sabatini, Chiara Macchi, Anna Alisi, Luca Miele, Giorgio Soardo, Giacomo Pietro Comi, Luca Valenti, Massimiliano Ruscica, Anna L. Fracanzani, Amalia Gastaldelli, Paola Dongiovanni
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 759-788 (2022)
Background & Aims: The I148M Patatin-like Phospholipase Domain-containing 3 (PNPLA3), the rs641738 in the Membrane bound O-acyltransferase domain containing 7-transmembrane channel-like 4 (MBOAT7-TMC4) locus, and the E167K Transmembrane 6 Superfamily
Externí odkaz:
https://doaj.org/article/f64f3d488c93467d921d79df5bc86b14
Autor:
Laura Manna, Eleonora Rizzi, Eleonora Bafile, Andrea Cappelleri, Massimiliano Ruscica, Chiara Macchi, Michele Podaliri Vulpiani, Romolo Salini, Emanuela Rossi, Concetta Panebianco, Francesco Perri, Valerio Pazienza, Federica Federici
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
IntroductionInflammatory bowel diseases (IBD) are chronic inflammatory conditions that typically involve diarrhea, abdominal pain, fatigue, and weight loss, with a dramatic impact on patients’ quality of life. Standard medications are often associa
Externí odkaz:
https://doaj.org/article/4e21ab400dac41a095e779eded521c5a