Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Chiara, Brignole"'
Autor:
Mario Capasso, Chiara Brignole, Vito A. Lasorsa, Veronica Bensa, Sueva Cantalupo, Enrico Sebastiani, Alessandro Quattrone, Eleonora Ciampi, Marianna Avitabile, Angela R. Sementa, Katia Mazzocco, Barbara Cafferata, Gabriele Gaggero, Valerio G. Vellone, Michele Cilli, Enzo Calarco, Elena Giusto, Patrizia Perri, Sanja Aveic, Doriana Fruci, Annalisa Tondo, Roberto Luksch, Rossella Mura, Marco Rabusin, Francesco De Leonardis, Monica Cellini, Paola Coccia, Achille Iolascon, Maria V. Corrias, Massimo Conte, Alberto Garaventa, Loredana Amoroso, Mirco Ponzoni, Fabio Pastorino
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Neuroblastoma (NB) represents the most frequent and aggressive form of extracranial solid tumor of infants. Although the overall survival of patients with NB has improved in the last years, more than 50% of high-risk patients stil
Externí odkaz:
https://doaj.org/article/dbb768f368d643d1a5a9f03a388be936
Autor:
Ezio Bonvini, Chiara Brignole, Enzo Calarco, Veronica Bensa, Elena Giusto, Patrizia Perri, Eleonora Ciampi, Maria Valeria Corrias, Simonetta Astigiano, Michele Cilli, Derik Loo, Fabio Pastorino, Mirco Ponzoni
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 9 (2023)
Introduction B7-H3 is a potential target for pediatric cancers, including neuroblastoma (NB). Vobramitamab duocarmazine (also referred to as MGC018 and herein referred to as vobra duo) is an investigational duocarmycin-based antibody-drug conjugate (
Externí odkaz:
https://doaj.org/article/c4e676297dc848ee96ef5ee33733a991
Autor:
Mirco Ponzoni, Tiziana Bachetti, Maria Valeria Corrias, Chiara Brignole, Fabio Pastorino, Enzo Calarco, Veronica Bensa, Elena Giusto, Isabella Ceccherini, Patrizia Perri
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-28 (2022)
Abstract Neuroblastoma (NB) is a pediatric tumor that originates from neural crest-derived cells undergoing a defective differentiation due to genomic and epigenetic impairments. Therefore, NB may arise at any final site reached by migrating neural c
Externí odkaz:
https://doaj.org/article/499ab520b9e04ba692ee13279c564d7e
Autor:
Daniela Di Paolo, Francesca Pontis, Massimo Moro, Giovanni Centonze, Giulia Bertolini, Massimo Milione, Mavis Mensah, Miriam Segale, Ilaria Petraroia, Cristina Borzi, Paola Suatoni, Chiara Brignole, Patrizia Perri, Mirco Ponzoni, Ugo Pastorino, Gabriella Sozzi, Orazio Fortunato
Publikováno v:
Molecular Oncology, Vol 15, Iss 11, Pp 2969-2988 (2021)
Lung cancer is the leading cause of cancer‐related death worldwide. Late diagnosis and metastatic dissemination contribute to its low survival rate. Since microRNA (miRNA) deregulation triggers lung carcinogenesis, miRNAs might represent an interes
Externí odkaz:
https://doaj.org/article/33a9e6effa634a75b63621df2c53eb15
Autor:
Davide Cangelosi, Chiara Brignole, Veronica Bensa, Roberto Tamma, Fabiana Malaguti, Barbara Carlini, Elena Giusto, Enzo Calarco, Patrizia Perri, Domenico Ribatti, Nuno André Fonseca, Joao Nuno Moreira, Alessandra Eva, Loredana Amoroso, Massimo Conte, Alberto Garaventa, Angela Rita Sementa, Maria Valeria Corrias, Mirco Ponzoni, Fabio Pastorino
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104300- (2022)
Summary: Background: Neuroblastoma (NB) represents the most frequent form of extra-cranial solid tumour of infants, responsible for 15% of childhood cancer deaths. Nucleolin (NCL) prognostic value in NB was investigated. Methods: NCL protein expressi
Externí odkaz:
https://doaj.org/article/7c7feb7bb2a447eba44682ff9676b2fb
Autor:
Federica Raggi, Davide Cangelosi, Alessandro Consolaro, Chiara Rossi, Simone Pelassa, Katia Cortese, Maria Cristina Gagliani, Martina Morini, Daniela Segalerba, Chiara Brignole, Paola Bocca, Danilo Marimpietri, Chiara Trincianti, Angelo Ravelli, Alessandra Eva, Maria Carla Bosco
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 10, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/7d2ad16cb17148b7aa55e95006763c59
Autor:
Chiara Brignole, Veronica Bensa, Nuno A. Fonseca, Genny Del Zotto, Silvia Bruno, Ana F. Cruz, Fabiana Malaguti, Barbara Carlini, Fabio Morandi, Enzo Calarco, Patrizia Perri, Vera Moura, Laura Emionite, Michele Cilli, Francesco De Leonardis, Annalisa Tondo, Loredana Amoroso, Massimo Conte, Alberto Garaventa, Angela R. Sementa, Maria V. Corrias, Mirco Ponzoni, Joao N. Moreira, Fabio Pastorino
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-13 (2021)
Abstract Background Neuroblastoma (NB) represents the most frequent and aggressive form of extracranial solid tumor of infants. Nucleolin (NCL) is a protein overexpressed and partially localized on the cell surface of tumor cells of adult cancers. Li
Externí odkaz:
https://doaj.org/article/74d59ac150f64c2ab3aaf5e3f878f108
Autor:
Fabio Pastorino, Mario Capasso, Chiara Brignole, Serena Giglio, Veronica Bensa, Sueva Cantalupo, Vito Alessandro Lasorsa, Annalisa Tondo, Rossella Mura, Angela Rita Sementa, Alberto Garaventa, Mirco Ponzoni, Loredana Amoroso
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11236 (2022)
Neuroblastoma (NB) is the most common extracranial solid tumor encountered in childhood. Although there has been significant improvement in the outcomes of patients with high-risk disease, the prognosis for patients with metastatic relapse or refract
Externí odkaz:
https://doaj.org/article/1195b54c0f9b40d39b51b6b67ca8cb07
Autor:
Fabio Pastorino, Chiara Brignole
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1114 (2022)
Cancer, the second leading cause of death worldwide, continues to represent an impressive challenge for researchers and clinicians [...]
Externí odkaz:
https://doaj.org/article/2fa279ba5e5140b38ac10e1f856289d3
Autor:
Enrico Rango, Fabio Pastorino, Chiara Brignole, Arianna Mancini, Federica Poggialini, Salvatore Di Maria, Claudio Zamperini, Giulia Iovenitti, Anna Lucia Fallacara, Samantha Sabetta, Letizia Clementi, Massimo Valoti, Silvia Schenone, Adriano Angelucci, Mirco Ponzoni, Elena Dreassi, Maurizio Botta
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 659 (2022)
Si306, a pyrazolo[3,4-d]pyrimidine derivative recently identified as promising anticancer agent, has shown favorable in vitro and in vivo activity profile against neuroblastoma (NB) models by acting as a competitive inhibitor of c-Src tyrosine kinase
Externí odkaz:
https://doaj.org/article/76fcd042be33447e9734d22a84d6e765